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A High Percentage of Early-age Onset Colorectal Cancer Is Potentially Preventable

  • Author Footnotes
    ∗ Authors share co-first authorship.
    Peter P. Stanich
    Footnotes
    ∗ Authors share co-first authorship.
    Affiliations
    Division of Gastroenterology, Hepatology & Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio
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  • Author Footnotes
    ∗ Authors share co-first authorship.
    Keith R. Pelstring
    Footnotes
    ∗ Authors share co-first authorship.
    Affiliations
    Genetic Counseling Graduate Program, The Ohio State University, Columbus, Ohio

    Department of Genetics, Dayton Children’s Hospital, Dayton, Ohio
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  • Heather Hampel
    Affiliations
    Department of Internal Medicine and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio
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  • Rachel Pearlman
    Correspondence
    Correspondence Address correspondence to: Rachel Pearlman, MS, LGC, Department of Internal Medicine and the Comprehensive Cancer Center, The Ohio State University, 2012 Kenny Road, Columbus, OH 43221.
    Affiliations
    Department of Internal Medicine and the Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio
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  • Author Footnotes
    ∗ Authors share co-first authorship.
Published:December 10, 2020DOI:https://doi.org/10.1053/j.gastro.2020.12.009
      Although overall colorectal cancer (CRC) rates have been decreasing, the incidence of early-age onset CRC (EAOCRC), defined as a CRC diagnosis before age 50 years, is increasing. This alarming trend has led to a focus on optimized screening recommendations.

      Abbreviations used in this paper:

      CRC (colorectal cancer), EAOCRC (early-age onset colorectal cancer), FDR (first-degree relative), OCCPI (Ohio Colorectal Cancer Prevention Initiative)
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