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Pancreatitis in Children

Published:February 01, 2019DOI:https://doi.org/10.1053/j.gastro.2018.12.043
      Acute, acute recurrent, and chronic forms of pancreatitis have been increasingly diagnosed in children in the past 2 decades. Risk factors in the pediatric group are broad and appear to be strikingly different compared with the adult cohort. However, the disease burden and impact on quality of life are surprisingly similar in children and adults. This review summarizes the definitions, epidemiology, risk factors, diagnosis, and management of pediatric pancreatitis, identifies features that are unique to the childhood-onset disease, identifies gaps, and proposes recommendations for future opportunities.

      Keywords

      Abbreviations used in this paper:

      AP (acute pancreatitis), ARP (acute recurrent pancreatitis), CP (chronic pancreatitis), EPI (exocrine pancreatic insufficiency), ERCP (endoscopic retrograde cholangiopancreatography), EUS (endoscopic ultrasound), INSPPIRE (International Study Group of Pediatric Pancreatitis: In Search for a Cure), PD (pancreatic duct), PRSS1 (cationic trypsinogen gene), SPINK1 (serine protease inhibitor Kazal type 1 gene), TPIAT (total pancreatectomy and islet autotransplantation)
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