Background & Aims
Abbreviations used in this paper:CRC (colorectal cancer), FAP (familial adenomatous polyposis), FDR (first-degree relative), MMR (mismatch repair), MSI (microsatellite instability), NGS (next-generation sequencing), VUS (variant of uncertain significance)
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Conflicts of interest The authors report no conflicts of interest related to this work.
Funding Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Numbers P30CA046592 and P50CA130810 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.