American Gastroenterological Association medical position statement: Evaluation of liver chemistry tests, This document presents the official recommendations of the American Gastroenterological Association (AGA) on the Evaluation of Liver Chemistry Tests. It was approved by the Clinical Practice Committee on March 3, 2002 and by the AGA Governing Board on May 19, 2002.


        The widespread availability and use of serum blood chemistries for screening both symptomatic and asymptomatic patients has resulted in a dramatic increase in the number of normal and abnormal liver chemistry tests that must be interpreted by physicians. Therefore, a rational approach for the appropriate evaluation of serum liver chemistries is essential for providing high-quality, cost-effective health care. Although there are no controlled clinical trials examining the optimal approach for evaluating serum liver chemistries, the following guidelines were developed to assist the gastroenterologist and primary care physician by providing them with a rational approach for the interpretation and further diagnostic evaluation of patients with abnormal liver chemistry tests.
        GASTROENTEROLOGY 2002;123:1364-1366
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          • Green RM
          • Flamm S.
          AGA technical review on the evaluation of liver chemistry tests.
          Gastroenterology. 2002; 123: 1367-1384