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2010 DDW Abstract Supplement

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4191 Articles:

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Abstract

pages i-iv
7 The Peripheral Histamine 1-Receptor Antagonist Fexofenadine Effectively Reverses Stress-Induced Visceral Hypersensitivity in a Rat Model of Maternal Separation

Oana I. Stanisor, Sophie A. van Diest, Olaf Welting, Cathy Cailotto, Jan van der Vliet, Wouter de Jonge, Guy E. Boeckxstaens, Rene M. van den Wijngaard et al. Abstract

page S-1
8 KitLow Interstitial Cell of Cajal Stem Cells are a Cell of Origin of Gastrointestinal Stromal Tumors

David T. Asuzu, Gwen A. Lomberk, Michael R. Bardsley, Yujiro Hayashi, Gianrico Farrugia, Raul A. Urrutia, Brian P. Rubin, Tamas Ordog et al. Abstract

page S-1
9 Tissue Trauma Induction of Gastrointestinal Ileus: An Innovative Murine Survival Model of Combat Injury and Its Consequences

Takeshi Tsukamoto, R. Savanh Chanthaphavong, Ihab I. El Hajj, Alexander Stojadinovic, Hiroyuki Yokota, Hans-Christoph Pape, Timothy Billiar, Anthony J. Bauer et al. Abstract

page S-1
10 Altered Gastrointestinal Motility and Reduced nNOS Neurons in TLR4 Mutant-Mice

Mallappa Anitha, Matam Vijay-Kumar, Shanthi V. Sitaraman, Andrew T. Gewirtz, Shanthi Srinivasan et al. Abstract

page S-1
11 Changes in Contractility, RMP and TRPC Channels in DSS-Colitis

Hyun J. Kim, Laura Dwyer, Sang D. Koh Abstract

pages S-1-S-2
12 Loss of Gastric Interstitial Cells of Cajal and Impaired Electrical Pacemaking in Klotho Mice, an Animal Model of Aging

Ferenc Izbeki, Andrea Lorincz, David T. Asuzu, Laura Popko, David L. Young, Michael R. Bardsley, Yujiro Hayashi, Makoto Kuro-o, Gianrico Farrugia, Tamas Ordog et al. Abstract

page S-2
13 Increasing Incidence of Barrett's Esophagus is Not Entirely Explained by Endoscopic Practice

Helen G. Mulholland, Shivaram Bhat, Liam Murray, Damian T. McManus, Anna T. Gavin, Brian T. Johnston et al. Abstract

page S-2
14 A Comparative Study of Dysplasia and Cancer Risk in Intestinal Metaplasia (IM) and Non-Intestinal Metaplasia Epithelia: Clinical Implications for the Definition of Barrett's Esophagus

Ajay Bansal, Mandeep Singh, Oksana Anand, Douglas H. McGregor, Philip G. Jones, Rachel Cherian, Vikas Singh, Srinivas Gaddam, Sachin B. Wani, Neil Gupta, Amit Rastogi, Prateek Sharma et al. Abstract

page S-2
15 Insulin Resistance and Central Adiposity as a Risk Factors for Barrett's Esophagus

Katarina B. Greer, Cheryl Thompson, Lacie Brenner, Beth Bednarchik, Gary W. Falk, William M. Grady, Joseph Willis, Gregory S. Cooper, Li Li, Amitabh Chak et al. Abstract

page S-2
16 A Segregation Analysis of Barrett's Esophagus and Associated Adenocarcinomas

Xiangqing Sun, Robert Elston, Jill Barnholtz-Sloan, Gary W. Falk, William M. Grady, Margaret F. Kinnard, Sumeet K. Mittal, Joseph Willis, Sanford Markowitz, Wendy E. Brock, Amitabh Chak et al. Abstract

pages S-2-S-3
17 Prior Endoscopy and Follow-up Strategies in Patients With High Grade Dysplasia in Barrett's Esophagus: A Dutch Population-Based Study

Romy E. Verbeek, Fiebo J. ten Kate, Marguerite E.I. Schipper, M.K. Casparie, Frank P. Vleggaar, Jantine W. van Baal, Peter D. Siersema et al. Abstract

page S-3
18 Overexpression of Mir-142-5p and Mir-155 and Suppression of Tumor Protein 53-Induced Nuclear Protein 1 in Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

Yoshimasa Saito, Hidekazu Suzuki, Hitoshi Tsugawa, Hiroyuki Imaeda, Juntaro Matsuzaki, Kenro Hirata, Naoki Hosoe, Masahiko Nakamura, Toshifumi Hibi et al. Abstract

page S-3
19 Gastric Tumor Development in SMAD3-Deficient Mice Initiates From Forestomach/Glandular Transition Zone Along the Lesser Curvature

Ki Taek Nam, Ryan L. O'Neal, Robert J. Coffey, James R. Goldenring Abstract

page S-3
20 IL-11 is a Parietal Cell Cytokine Which Promotes Neoplastic Progression

Meegan Howlett, Katrina Bell, Ian van Driel, Nhung Nguyen, Andrew S. Giraud, Louise M. Judd et al. Abstract

page S-3
21 TFF2 Inhibits Tumour Growth and is a Target for Epigenetic Silencing in Gastric Cancer

Trevelyan Menheniott, Anthony J. Peterson, Louise O'Connor, Timothy C. Wang, James G. Fox, Toshinari Minamoto, Kazyuki Kawakami, Louise M. Judd, Andrew S. Giraud et al. Abstract

pages S-3-S-4
22 Epigenetic Identification of Paired Box Gene 5 as a Functional Tumor Suppressor Associated With Poor Prognosis in Patients With Gastric Cancer

Xiaoxing Li, Kin-Fai Cheung, Junhong Zhao, Xiaowei Ma, Minnie Y. Go, Eagle SH Chu, Alfred S. Cheng, Qian Tao, Joseph J. Sung, Hsiang-fu Kung, Jun Yu et al. Abstract

page S-4
23 Overexpression of Stromal Cell-Derived Factor-1 Induces Gastric Atrophy, and Expansion and Migration of DCAMKL-1 Positive Putative Progenitor Cells

Wataru Shibata, Alexander Dubeykovskiy, Michael Quante, Shigeo Takaishi, Zinaida Dubeikovskaya, Hiroyuki Tomita, Kelly S. Betz, Timothy C. Wang et al. Abstract

page S-4
24 Epithelial iNOS Impairs Tight Junctions Leading to Bacterial Translocation via Pkczeta Activation and Rho-ROCK-Dependent Myosin Light Chain Phosphorylation in Obstructed Guts

Li-Ling Wu, Hsin-Da Chiu, Yen-Zhen Lu, Linda C.H. Yu Abstract

page S-4
25 Early-Life Dysbiosis Leads to Visceral Hypersensitivity in Adulthood

Siobhain M. O'Mahony, Helene M. Savignac, Timothy O'Brien, Paul Scully, Eamonn M. Quigley, Julian Marchesi, Paul W. O'Toole, Timothy G. Dinan, John F. Cryan et al. Abstract

pages S-4-S-5
26 Enteropathogenic E. coli Secreted Protein F Interaction With Sorting Nexin 9 Induces Clathrin-Dependent Membrane Remodeling and Bacterial Invasion of Intestinal Epithelial Cells Independent of Dynamin Activity

Andrew W. Weflen, Neal M. Alto, Gail A. Hecht Abstract

page S-5
27 Bile Acids Improve the Bioavailability and Bactericidal Effect of Rifaximin

Charles Darkoh, Lenard M. Lichtenberger, Nadim Ajami, Elizabeth Dial, Zhi-Dong Jiang, Herbert L. DuPont et al. Abstract

page S-5
28 PI3K Signaling Mediates Campylobacter Jejuni Induced Colitis in IL 10-/- Mice

Xiaolun Sun, Joshua M. Uronis, Ward Jarvis, Sandra C. Kim, Christian Jobin et al. Abstract

page S-5
29 Fecal Bacteriotherapy for Recurrent Clostridium difficile Infection

Perttu E. Arkkila, Raija Uusitalo-Seppälä, Laura Lehtola, Veikko Moilanen, Matti Ristikankare, Eero J. Mattila et al. Abstract

page S-5
30 Variants in Znf365 on 10q21 are Associated With Crohn's Disease

Talin Haritunians, Michelle R. Jones, Dermot P. McGovern, Phillip Fleshner, Andrew Ippoliti, Marla Dubinsky, Eric A. Vasiliauskas, Gil Y. Melmed, David Q. Shih, Robert Barrett, Jerome I. Rotter, Stephan R. Targan, Kent D. Taylor et al. Abstract

page S-6
31 Putative Genetic Loci and Confirmation of Association in IBD

Saad Pathan, Joanne M. Stempak, Wei Xu, Thomas D. Walters, Anne M. Griffiths, Gordon R. Greenberg, Hillary Steinhart, Mark S. Silverberg et al. Abstract

page S-6
32 Effect of Inflammatory Bowel Diseases Phenotype and NOD2 Genotype on Ileal Associated Microbiota

Christina M. Hamm, Jeffrey Yuan, Ellen Li, Tianyi Zhang, Hongyan Chen, Wei Zhu, R. Balfour Sartor, Edgar C. Boedeker, Noam Harpaz, Daniel Frank et al. Abstract

page S-6
33 The GTPase RAC1 is Associated With Inflammatory Bowel Disease

Aleixo M. Muise, Thomas D. Walters, Wei Xu, Grace Shen-Tu, Grace Y. Lam, Joshua D. Bennitz, Johan Van Limbergen, Conghui Guo, Bo-Yee Ngan, Philip M. Sherman, Richard H. Duerr, Judy H. Cho, Jack Satsangi, David C. Wilson, Anne M. Griffiths, Michael Glogauer, Mark S. Silverberg, John Brumell et al. Abstract

page S-6
34 A Meta-Analysis of Genome Wide Association Scans Identifies TAGAP and Pus10 as Shared Risk Loci for Crohn's Disease and Celiac Disease

Eleonora A. Festen, Philippe Goyette, Todd Green, Claudine Beauchamp, Caroline Lagace, Gabrielle Boucher, Gosia Trynka, Patrick C. Dubois, Pieter Stokkers, Daniel W. Hommes, Donatella Barisani, Orazio Palmieri, Vito Annese, David van Heel, Rinse K. Weersma, Mark J. Daly, Cisca Wijmenga, John D. Rioux et al. Abstract

page S-7
35 Gene-Environment Interactions in Crohn's Disease: Identification of a Novel SNP That Interacts Strongly With Smoking to Shorten Time to First Resection

Graham L. Radford-Smith, Hae K. Im, Phil Schumm, Lisa Simms, Ning Huang, Maria Ikonomopoulou, Yashoda Sharma, Judy H. Cho, Dan L. Nicolae et al. Abstract

page S-7
36 Synergy Between the Thyroid Hormone Receptor Trα1 and the Wnt/β-Catenin in the Induction of Intestinal Tumors in the Mouse

Maria Sirakov, Seham Skah, Michela Plateroti Abstract

page S-7
37 The Absence of LPA2 Suppresses Adenomatous Polyposis Coli-Dependent Intestinal Tumorigenesis

Songbai Lin, Sei-Jung Lee, Simon M. Mwangi, Shanthi Srinivasan, Hyunsuk Shim, C.C. Yun et al. Abstract

page S-7
38 Scribble-Mediated Membrane Targeting of PHLPP1 is Required for Its Tumor Suppressor Function

Xin Li, Tianyan Gao Abstract

page S-7
39 Stromal TWIST1 Expression Increases Together With Local Invasion in Microsatellite-Stable Colorectal Cancers

Luigi Laghi, Giuseppe Celesti, Paolo Bianchi, Giuseppe Di Caro, Fabio Grizzi, Lucia Fini, Massimo Roncalli, Alberto Malesci et al. Abstract

pages S-7-S-8
40 Increased Extracellular Pressure Stimulates NF-kB Activation and Cellular Proliferation in Cancer Cells

Christina Downey, James S. Hatfield, Jetze Tepe, Marc D. Basson Abstract

page S-8
41 Colonic Extracellular Calcium-Sensing Receptor (CaSR) Inhibits M-Calpain Activity by Increasing Calmodulin to Cause M-Calpain Autolysis

Vinay Singh, Jacqueline Kelly, R. John MacLeod, Zongchao Jia Abstract

page S-8
41a Prediction of Long-Term Clinical Remission for Adalimumab-Treated Patients With Crohn's Disease by Identification of Appropriate Dichotomizing Points for SES-CD

Walter Reinisch, Paul J. Rutgeerts, Remo Panaccione, Geert R. D'Haens, Roopal Thakkar, Andrew P. Yu, Zhiyi Li, Anne A. Camez, Paul F. Pollack, Mei Yang, Jingdong Chao, Parvez Mulani et al. Abstract

page S-8
42 Appropriateness of Therapy for Fistulizing Crohn's Disease: Findings From a Nationwide Inflammatory Bowel Disease Cohort

Valérie Pittet, Pascal Juillerat, Pierre F. Michetti, John-Paul Vader, Bernard Burnand, Gerhard Rogler, Christoph Beglinger, Frank Seibold, Christian Mottet, Christian P. Felley, Jean-Jacques Gonvers, Florian Froehlich et al. Abstract

page S-8
43 Impact of Psychiatric Disorders on Patients With Crohn's Disease: An Analysis Based on a Healthcare Claims Database

Chenglong Han, Ning Zhao, Marion Blank, Christopher Gasink Abstract

page S-9
44 Patients With Crohn's Disease Treated With Certolizumab Pegol Experienced Long-Term Remission Regardless of Prior TNF-α Inhibitor Exposure (PRECiSE 4 Study)

William J. Sandborn, Stefan Schreiber, Stephen B. Hanauer, Jean-Frederic Colombel, Ralph Bloomfield, Gary Lichtenstein et al. Abstract

page S-9
45 Small Intestine Contrast Ultrasonography (SICUS) for the Detection of Intestinal Complications in Crohn's Disease: A Prospective Comparative Study Versus Intraoperative Findings

Nadia Pallotta, Giuseppina Vincoli, Erminia Romeo, Barbara Ciccantelli, Chiara Montesani, Piero Chirletti, Anna Maria Pronio, Luigi Dall'Oglio, Naima Abdulkadir Hassan, Enrico Corazziari et al. Abstract

page S-9
46 A Phase 2a Randomized Placebo-Controlled Double-Blind Multi-Center Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Patients With Moderately Active Ulcerative Colitis

Severine Vermeire, Paul J. Rutgeerts, Geert R. D'Haens, Martine De Vos, Brian Bressler, Annegret Van der Aa, Bernard Coulie, Cindy J. Wong, Brian G. Feagan et al. Abstract

page S-9
47 Prevalence of Elevated Serum Immunoglobulin G4 in a Population Based Cohort of Primary Sclerosing Cholangitis

Maria Benito de Valle, Einar Bjornsson, Björn Lindkvist Abstract

pages S-9-S-10
48 The Risk of Fresh Frozen Specimen-Dependent R0 Resection for Hilar Cholangiocarcinoma

Takuya Miura, Shinji Tsutsumi, Daisuke Kudo, Keinosuke Ishido, Yoshikazu Toyoki, Shunji Narumi, Kenichi Hakamada et al. Abstract

page S-10
49 Temporary Placement of Fully Covered Self-Expandable Metallic Stents for Benign Biliary Strictures. Preliminary Results – A Prospective Multicenter Study

Ulriikka Chaput, Marianne Gaudric, Philippe Bichard, Paul Bauret, Dimitri Coumaros, Bruno Vedrenne, Bertrand Napoleon, Ariane Chryssostalis, Stanislas Chaussade, Frederic Prat et al. Abstract

page S-10
50 A Genome-Wide Scan Identifies TM4SF4 (Intestine and Liver Tetraspan Membrane Protein 4) as a Susceptibility Locus for Gallstone Disease

Clemens Schafmayer, Alexander Teumer, Stephan Buch, Astrid Petersmann, Jan H. Egberts, Georg Homuth, Allan Linneberg, Alexander Arlt, Juan F. Miquel, Flavio Nervi, Dieter Bröring, Markus M. Lerch, Ulrich John, Wolfgang Hoffmann, Stefan Schreiber, Torben Jorgensen, Reiner H. Biffar, Jochen Hampe, Henry Völzke et al. Abstract

page S-10
51 Desipramine Can Reduce Diet-Induced Cholesterol Gallstone Formation by Inhibition of Ceramide Biosynthesis in Mice

Seung Goun Hong, Jae Seon Kim, Jin Ki Hwang, Moon Kyung Joo, Eun Suk Jung, Ji Hoon Kim, Jong Eun Yeon, Jong-Jae Park, Kwan Soo Byun, Young-Tae Bak, Seikwan Oh, Youn-Sun Lee, Hwan-Soo Yoo et al. Abstract

page S-10
52 Timing of Appearance of Gallbladder and Gastric Dysmotility in Gallstone-Free Obese Subjects From Different Age Classes. A Clue for Gallstone Disease in Adults?

Agostino Di Ciaula, David Q. Wang, Piero Portincasa Abstract

pages S-10-S-11
53 From Pancreatic Intraepithelial Neoplasia (PanIN) to Intraductal Papillary Mucinous Neoplasms (IPMN): What is the Significance of Endoscopic Ultrasound Findings?

Frédérique Maire, Anne Couvelard, Laurent Palazzo, Alain Aubert, Marie-Pierre Vullierme, Pascal Hammel, Philippe Levy, Vinciane Rebours, Alain Sauvanet, Safi Dokmak, Philippe B. Ruszniewski et al. Abstract

page S-11
54 The Feasibility of Determining the Malignant Potential of Pancreatic Cysts Using Partial Wave Spectroscopic Microscopy

David Y. Lo, Yang Liu, Rajan K. Bista, Walid E. Khalbuss, Sarah Navina, Sara E. Monaco, Randall Brand et al. Abstract

page S-11
55 Antioxidants in the Aetiology of Pancreatic Cancer: A UK Prospective Cohort Study Using Data From Food Diaries

Paul R. Banim, Robert Luben, Alison McTaggart, Nick Wareham, Kay-Tee Khaw, Andrew Hart et al. Abstract

page S-11
56 Endoscopic Ultrasound (EUS) vs Helical CT Scan for TN Staging and Evaluation of Resectability of Pancreatic Cancer: A Prospective, Comparative Study Using Histology of Surgical Specimens as Gold-Standard

Julio Iglesias-Garcia, Ana Alvarez-Castro, Jose Iglesias-Canle, Jose Larino-Noia, Gerardo Pazos, Jeronimo Forteza, Evaristo Varo, Enrique Dominguez-Munoz et al. Abstract

page S-11
57 Proteomics is More Sensitive and Accurate Than Current Standard Cyst Fluid Analyses in the Clinical Assessment of Pancreatic Cystic Lesions

Karolina E. Sjöberg, Malin E. Johansson, Anders G. Hyltander, Morteza Shafazand, Jan Hansen, Henrik Sjovall, Gunnar C. Hansson, Riadh Sadik et al. Abstract

pages S-11-S-12
58 Comprehensive Mass Spectrometry Based Metabolomic Profiling of Blood Plasma Reveals Potent Discriminatory Classifiers of Pancreatic Adenocarcinoma

Shiro Urayama, Wei Zou, Vladimir Tolstikov Abstract

page S-12
59 HCL-Induced Release of Inflammatory Mediators by the Esophageal Mucosa Stimulates Leukocyte Migration and Production of H2O2

Jie Ma, Annamaria Altomare, Suzanne M. de la Monte, Ming Tong, Florian Rieder, Claudio Fiocchi, Jose Behar, Piero Biancani, Karen M. Harnett et al. Abstract

page S-12
60 Acoustic Cough-Reflux Associations in Chronic Cough: Potential Triggers and Mechanisms

Jaclyn A. Smith, Sam Decalmer, Angela Kelsall, Kevin McGuinness, Ashley Woodcock, Lesley A. Houghton et al. Abstract

page S-12
61 Structure and Function of the Gastro-Esophageal Junction in Patients After Laparoscopic Fundoplication: Combined Magnetic Resonance Imaging (MRI) and High Resolution Manometry (HRM) Studies

Elad Kaufman, Michael Wyss, Jelena Curcic, Zsofia Forras-Kaufman, Paul M. Schneider, Marc Schiesser, Werner Schwizer, Michael Fried, Peter Boesiger, Mark R. Fox et al. Abstract

page S-12
62 Use of the Hospital Odynophagia Dysphagia Questionnaire as a Measure of Patient Reported Outcome in a Comparative Analysis of Achalasia Treatments

Neha V. Patel, Sean T. McCarthy, Monika A. Kwiatek, John E. Pandolfino, Peter J. Kahrilas et al. Abstract

page S-13
63 Aerodigestive Protective Reflexes are Triggered Before the Safe Capacity of Pharynx is Exceeded

Sri Naveen Surapaneni, Kulwinder S. Dua, Shiko Kuribayashi, Muhammad Hafeezullah, Manuel A. Amaris, Reza Shaker et al. Abstract

page S-13
64 Diagnostic (Dis)agreement Between Conventional Manometry Criteria and the Chicago Classification of Esophageal Motility Disorders in Tertiary Care Patients

Sebastien Kindt, Nathalie Rommel, Jan F. Tack Abstract

page S-13

4191 Articles: