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SOCS3 Expression is a Predictive Factor of Relapse of Mucosal Inflammation in Chronic UC
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Yi Li,
Colin de Haar,
Veerle J. Nuij,
Judith E. Baars,
Ernst J. Kuipers,
Christien J. van der Woude
et al.
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S-1
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Early Involvement of Liver Natural Killer T Cells in Limiting Colonic Inflammation and Application to Disease Treatment
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Dania Chakass,
Haifa Hamdi,
Christelle Faveeuw,
Benjamin Bertin,
Edmone Erdual,
Matthieu Allez,
Benedicte De Vroey,
Jostte Fontaine,
Caroline Dubuquoy,
Mathias Chamaillard,
Noura El-Jamal,
Jean-Frederic Colombel,
François Trottein,
Laurent Dubuquoy,
Pierre Desreumaux
et al.
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S-1
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Isolated Active Ileitis: Serological and Genetic Profile
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Sarah O'Donnell,
Maria O'Sullivan,
Niall Breslin,
Humphrey J. O'Connor,
Colm A. O'Morain,
Paul L. Crotty,
Barbara M. Ryan
et al.
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S-1
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The Role of FC Gamma Receptor (FCGR) Mutations in the Response to Infliximab in Inflammatory Bowel Disease
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Maria Teresa Arias,
Isabelle Cleynen,
Karolien Claes,
David Drobne,
Ann Gils,
Matthias Jürgens,
Marc Ferrante,
Vera Ballet,
Gert A. Van Assche,
Paul J. Rutgeerts,
Severine Vermeire
et al.
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S-1
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The Inflammatory Bowel Disease (IBD) Signal Transducer and Activator of Transcription 3(STAT3) Risk Allele is Associated With Increased Interleukin-6(IL-6)/STAT3 Activation in Epstein-Barr Virus(EBV) Transformed B Lymphocytes From Pediatric IBD Patients
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Benjamin Kuhn,
Ingrid Jurickova,
Stephen L. Guthery,
Lee Denson
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S-1-S-2
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Granulocyte-Macrophage Colony Stimulating Factor Auto-Antibodies Are Produced by Lamina Propria Mononuclear Cells Isolated From Ileal Strictures of Pediatric Patients With Crohn Disease Undergoing Ileo-Cecal Resection
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Ingrid Jurickova,
Claudia Chalk,
Bruce C. Trapnell,
Lee Denson
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S-2
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Pharmacodynamic Effects of Dronabinol, a Non-Selective Cannabinoid Receptor Agonist, on Colonic Sensory and Motor Functions in Irritable Bowel Syndrome
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Banny S. Wong,
Michael Camilleri,
Irene A. Busciglio,
Lawrence A. Szarka,
Duane D. Burton,
Alan R. Zinsmeister
et al.
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S-2
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Clomipramine Reduces Visceral Perception-Related Brain Activation in Humans
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Shin Fukudo,
Namiko Itoh,
Motoyori Kanazawa,
Satoshi Watanabe,
Toyohiro Hamaguchi,
Joe Morishita,
Michiko Kano,
Manabu Tashiro
et al.
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S-2
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A Prospective, Randomized, Placebo-Controlled Double-Blind, Dose-Escalation Trial of Pyridostigmine for Diabetes Mellitus and Constipation
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Adil E. Bharucha,
Phillip A. Low,
Michael Camilleri,
Duane D. Burton,
Yogish C. Kudva,
Pankaj Shah,
Alan R. Zinsmeister
et al.
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S-2-S-3
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A3309, an Ileal Bile Acid Transport (IBAT /ASBT) Inhibitor, Significantly Improved Stool Frequency and Other Constipation-Related Complaints in Adults With Chronic Constipation: Data From an 8-Week, Randomized, Double-Blind, Placebo-Controlled Study
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William D. Chey,
Michael Camilleri,
Lin Chang,
Leif Rikner,
Hans Graffner
et al.
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S-3
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Impact of Bile Acids on IBS Symptoms and the Effects of Resin Treatment
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Antal Bajor,
Mats Rudling,
Kjell-Arne Ung,
Jenny Wallin,
Magnus Simren
et al.
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S-3
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Is the Effect of Lubiprostone on Clinical Pain Mediated by Decreases in Visceral Pain Sensitivity?
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Olafur S. Palsson,
Marsha J. Turner,
Jane Tucker,
William E. Whitehead
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S-3
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NIBP/NfκB Signaling Regulates Neuronal Differentiation of Enteric Neural Stem Cells
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Yonggang Zhang,
Fang Li,
Wenhui Hu
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S-3-S-4
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NaHS Facilitates Fast Cholinergic Synaptic Input From Central Preganglionic Nerves in Mouse Superior Mesenteric Ganglion
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Lei Sha,
David R. Linden,
Gianrico Farrugia,
Joseph H. Szurszewski
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S-4
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How Varicella Zoster Virus (VZV) Gets Into the Enteric Neurons and Establishes Latency: A Route via Dorsal Root Ganglion Neurons That Doubly Project the Epidermis and the Bowel
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Jason J. Chen,
Zhishan Li,
Robert A. Cowles,
Michael D. Gershon,
Anne A. Gershon
et al.
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S-4
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Infection of Human Enteroendocrine Cells With C. Trachomatis as a Model for Irritable Bowel Syndrome
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Aldona Dlugosz,
Katherina Zakikhany,
Sandra Muschiol,
Kjell Hultenby,
Greger Lindberg
et al.
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S-4
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Transient Induction of RET Activity Pushes CNS Neural Stem Cells Towards Enteric Phenotype Through Activation of Multiple Signaling Pathways
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Gunjan Tiwari,
Maria-Adelaide Micci,
Subhash Kulkarni,
Laren Becker,
Johann Peterson,
Pankaj J. Pasricha
et al.
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S-4
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Measuring Nerve Activity in Routine Human Intestinal Biopsies
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Carla Cirillo,
Jan F. Tack,
Pieter Vanden Berghe
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S-4-S-5
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Prevalence of Red Blood Cell Alloantibodies in Patients With Inflammatory Bowel Disease – A Prospective Study
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Pavol Papay,
Klaus Hackner,
Harald Vogelsang,
Gottfried Novacek,
Christian Primas,
Walter Reinisch,
Alexander Eser,
Clemens Dejaco,
Andrea Mikulits,
Günther F. Körmöczi
et al.
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S-5
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Impaired Intestinal Iron Absorption in Inflammatory Bowel Disease Correlates With Disease Activity and Markers of Inflammation but is Independent of Disease Location
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Stefan Marcel Loitsch,
Daniela Diehl,
Franz Hartmann,
Axel U. Dignass,
Jürgen Stein
et al.
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S-5
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Clinical, Serologic, and Genetic Associations With Low Bone Density in Patients With Inflammatory Bowel Disease
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Arushi M. deFonseka,
Talin Haritunians,
Dror Berel,
Stephan R. Targan,
Carol J. Landers,
Jerome I. Rotter,
Eric A. Vasiliauskas,
Andrew Ippoliti,
Gil Y. Melmed,
David Q. Shih,
Marla Dubinsky,
Kent D. Taylor,
Dermot P. McGovern
et al.
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S-5
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Does the Development of Primary Sclerosing Cholangitis in IBD Require the Presence of Colonic Inflammation?
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Aoibhlinn M. O'Toole,
Alaa Alakkari,
Denise Keegan,
Glen A. Doherty,
Hugh Mulcahy,
Diarmuid P. O'Donoghue
et al.
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S-5
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Work Disability in Inflammatory Bowel Disease: First Results From the COIN study
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Mirthe E. van der Valk,
Marie-Josée J. Mangen,
Martijn G. van Oijen,
Peter D. Siersema,
Bas Oldenburg
et al.
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S-6
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A Prospective Population-Based Study of Symptoms and Life Stresses in Active and Inactive IBD
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Sunny Singh,
Andrea K. Blanchard,
John R. Walker,
Lesley A. Graff,
Norine Miller,
Charles N. Bernstein
et al.
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S-6
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VEGF Inhibitors Induce Cellular Senescence in Colorectal Cancers
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Mohammad R. Hasan,
Shirley Ho,
David A. Owen,
Isabella T. Tai
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S-6
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CD24 Co-Localises With DCAMKL-1 in the Intestine and Regulates Epithelial Apoptosis and Crypt Regeneration Following Damage Inducing Stimuli
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Carrie A. Duckworth,
Daniel Clyde,
David M. Pritchard
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S-6
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C-Terminal Phosphorylation of β-Catenin Increases Wnt Signaling and Intestinal Tumorigenesis
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Wendy van Veelen,
Ngoc Hang Le,
Werner Helvensteijn,
Lau Blonden,
Myrte Theeuwes,
Elvira Bakker,
Patrick Franken,
Leon Van Gurp,
Frits Meijlink,
Martin A. Van der Valk,
Ernst J. Kuipers,
Riccardo Fodde,
Ron Smits
et al.
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S-6-S-7
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Targeting the EP1-FasL Signaling Pathway Reduces Colon Tumor Cell Growth In Vivo
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Grace P. O'Callaghan,
Peter Neary,
Caitlin O'Mahony,
Fergus Shanahan,
Aileen Houston
et al.
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S-7
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Intestine-Specific Expression of K-RASG12d From the Endogenous K-RAS Locus Leads to a Hyperproliferative Intestinal Phenotype and Spontaneous Polyposis
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Mandayam O. Nandan,
Amr Ghaleb,
Vincent W. Yang
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S-7
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Stabilization of Survivin mRNA Through the RNA Binding Protein Cug-Bp1 Enhances Resistance to Apoptosis in Human Esophageal Epithelial Cells
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Elizabeth Tsuying Chang,
James M. Donahue,
Jian-Ying Wang,
Richard Battafarano
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S-7
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Humanized Monoclonal Antibodies Against Clostridium difficile Toxins Have Potent Activity in a Hamster Model for CDAD
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Andre Marozsan,
William Olson
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S-7
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Toward a Vaccine for Enterotoxigenic E.Coli (ETEC): A Live Attenuated Enterohemorrhagic E.Coli (EHEC) Strain Expressing ETEC Antigens is Immunognenic and Protective
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Wyatt Byrd,
Edgar C. Boedeker
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S-7-S-8
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Targeting the mTOR Signaling Prevents and Treats Campylobacter Jejuni-Induced Colitis
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Xiaolun Sun,
Christian Jobin
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S-8
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Microbiota From Colon Cancer Patients Induces Intestinal Epithelial Cell Proliferation in Germ-Free Mice
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Jarrousse Veronique,
Sandra Guilmeau,
Blugeon Sebastien,
Jean-Pierre Furet,
Roperch Jean-Pierre,
Auriault Marie Luce,
Philippe Langella,
Sobhani Iradj,
Andre Bado
et al.
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S-8
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EHEC Infection Stimulates Macropinocytosis and Transcellular Transcytosis of Shiga Toxin 1 in Intestinal Epithelial Cells by a Myosin II-Dependent Mechanism
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Valeriy Lukyanenko,
Ann Hubbard,
Michael Delannoy,
Edgar C. Boedeker,
Olga Kovbasnjuk
et al.
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S-8
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EPEC ESPF Disrupts Tight Junction Barrier Function Through Direct Interaction With 14-3-3
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Kim Hodges,
Athanasia Koutsouris,
Gail A. Hecht
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S-8
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Bacterial Factors Other Than Injected CagA and Those Mediating IL-8 Induction Participate in H. pylori-Mediated Gastric H,K-ATPase Repression
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Yong-Mei Zhang,
Charles E. Hammond,
Richard M. Peek,
Steffen Backert,
Adam J. Smolka
et al.
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S-9
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Up-Regulation of the Helicobacter pylori Receptor Decay-Accelerating Factor is Mediated by Peptidoglycan-Dependent Activation of NOD1
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Lydia E. Wroblewski,
Jennifer M. Noto,
Judith Romero-Gallo,
Alberto G. Delgado,
M. Blanca Piazuelo,
Giovanni Suarez,
Dawn Israel,
Pelayo Correa,
Dana Philpott,
Richard M. Peek
et al.
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S-9
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Protein Trafficking Involving the HP0165/HP0166 Two-Component System (TCS) of Helicobacter pylori Plays an Important Role in Acid Acclimation
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Elizabeth A. Marcus,
George Sachs,
Yi Wen,
Jing Feng,
David R. Scott
et al.
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S-9
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A Small RNA Determines the up and Down Role of the Hp0165-Hp0166 Two Component System in the Response of Helicobacter pylori to Varying Gastric pH
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George Sachs,
David R. Scott,
Jing Feng,
Elizabeth A. Marcus,
Yi Wen
et al.
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S-9
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H. pylori-Derived Oncoprotein, CagA, is Degraded by Autophagy in Human Gastric Epithelial Cells
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Hitoshi Tsugawa,
Hidekazu Suzuki,
Masanori Hatakeyama,
Juntaro Matsuzaki,
Kenro Hirata,
Sawako Okada,
Seiichiro Fukuhara,
Toshifumi Hibi
et al.
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S-10
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In Vivo Immunohistochemistry With Labeled Bevacizumab Using Confocal Laser Endomicroscopy in Models of Human Colorectal Cancer
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Sebastian Foersch,
Ralf Kiesslich,
Michael S. Hoetker,
Peter R. Galle,
Markus F. Neurath,
Martin Goetz
et al.
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S-10
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Miami Classification of Probe-Based Confocal Laser Endomicroscopy (pCLE) Findings for the Characterization of Indeterminate Strictures: First Steps Towards Automated Patient Segmentation?
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Adam Slivka,
Yang K. Chen,
Douglas K. Pleskow,
Peter D. Stevens,
Raj J. Shah,
Ram Chuttani,
Alexander Meining
et al.
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S-10
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Silencing of CD98 Expression Using a Nanoparticle-Based Delivery System Ameliorates Induced Colitis in Mice
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Hamed Laroui,
Yutao Yan,
Hang Thi Thu Nguyen,
Guillaume Dalmasso,
Moiz A. Charania,
Saravanan Ayyadurai,
Shanthi V. Sitaraman,
Didier Merlin
et al.
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S-10-S-11
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Endoscopic Optical Biopsy of Experimental Colitis Associated Cancer Using a Gamma-Glutamyltransferase Activatable Fluorescence Imaging Probe
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Makoto Mitsunaga,
Nobuyuki Kosaka,
Peter L. Choyke,
Matthew R. Young,
Nancy H. Colburn,
Masayo Sakabe,
Tetsuo Nagano,
Yasuteru Urano,
Hisataka Kobayashi
et al.
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S-11
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In Vivo Multi-Spectral Wide-Field Fluorescence Detection of Dysplasia in the Mouse
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Sharon J. Miller,
Cameron M. Lee,
Bishnu P. Joshi,
Eric J. Seibel,
Thomas D. Wang
et al.
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S-11
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Admission Clinical Scores in Predicting Persistent Organ Failure in Acute Pancreatitis: A Head-to-Head Comparison and Design of Novel Step-up Classification Rules
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Rawad Mounzer,
Christopher J. Langmead,
Anna C. Evans,
Faraz Bishehsari,
John Y. Nasr,
Dhiraj Yadav,
David C. Whitcomb,
Georgios I. Papachristou
et al.
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S-11
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Endoscopic Versus Surgical Necrosectomy for Patients With Symptomatic Pancreatic Necrotic Collections: A Retrospective Cohort Study
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Inbar S. Spofford,
Bechien U. Wu,
Darwin Conwell,
Peter A. Banks,
Koenraad J. Mortele,
Ramin Khorasani,
Song Yu,
Christopher C. Thompson
et al.
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S-11-S-12
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Long Term Outcomes Following Dual Modality Drainage of Organized Pancreatic Necrosis
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Andrew S. Ross,
Michael Gluck,
Shayan Irani,
S. Ian Gan,
Mehran Fotoohi,
Ellen Hauptmann,
Robert Crane,
Justin Siegal,
Richard A. Kozarek
et al.
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S-12
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Pre-Existing Cardiovascular Disease (CVD) Predicts Severe Post-ERCP Pancreatitis (SPEP)
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Joshua P. Spaete,
Sameer D. Saini,
Darren D. Ballard,
Erik J. Wamsteker,
Matthew J. DiMagno
et al.
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S-12
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Hematocrit, Creatinine, and Blood Urea Nitrogen in the Assessment of Pancreatic Necrosis in Acute Pancreatitis: An International Study
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Georgios I. Papachristou,
Bechien U. Wu,
Olaf J. Bakker,
Christopher J. Langmead,
Kathryn Repas,
Marc G. Besselink,
Rawad Mounzer,
Hjalmar C. van Santvoort,
Peter A. Banks,
Hein G. Gooszen,
David C. Whitcomb
et al.
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S-12-S-13
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The Effect of Early Aggressive Fluid Resuscitation on Morbidity and Mortality in Acute Pancreatitis
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Matthew G. Warndorf,
Jane T. Kurtzman,
Michael J. Bartel,
Mougnyan Cox,
Todd A. Mackenzie,
Paul Burchard,
Stuart R. Gordon,
Timothy B. Gardner
et al.
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S-13
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Altered Stem Cell Dynamics in Human Colon Adenoma Crypts Allow Rapid Expansion and Fixation of Mutations During Clonal Expansion
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Adam Humphries,
Trevor A. Graham,
Anna M. Nicholson,
Stuart A. McDonald,
Nicholas A. Wright
et al.
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S-13
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Single Cell Gene Expression Profiling of Adult Murine Colon Provides Novel Insight Into Both the Origin of Stem Cells and Their Supportive Cell Type
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Michael E. Rothenberg,
Tomer Kalisky,
Piero D. Dalerba,
Ysbrand Nusse,
Stephen Quake,
Michael F. Clarke
et al.
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S-13-S-14
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Dynamic Network Modeling of Epithelial-to-Mesenchymal Transition Determines Snail1 as Critical Driver of Stemness in Liver Cancer
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C.B. Rountree,
Steve Steinway,
Hien Dang,
Wei Ding,
Reka Albert
et al.
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S-14
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CD24 as a Potential Marker to Directly Isolate LGR5+ Colonic Epithelial Cells
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Jeffrey B. King,
Richard J. von Furstenberg,
Susan J. Henning
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S-14-S-15
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Embryonic Stem Cell Incorporation in Gastric Wall is Enhanced by Modified Proinflammatory Stem Cells and Enhanced Proliferative Host Compartment
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Hiroshi Mashimo,
Shan Gong,
Qin Huang
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S-15
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The Life-Cycle of Human Colon Crypts
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Trevor A. Graham,
Stuart A. McDonald,
Adam Humphries,
Nicholas A. Wright
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S-15
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Patient and Colonoscopy Factors Influencing Adenoma Detection in Patients Undergoing Colonoscopy in the NHS Bowel Cancer Screening Programme
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Tom J. Lee,
Colin Rees,
Roger G. Blanks,
Sue Moss,
Claire Nickerson,
Karen Wright,
Peter W. James,
Richard J. McNally,
Julietta Patnick,
Matthew D. Rutter
et al.
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S-15
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Once-Only Sigmoidoscopy Screening for Colorectal Cancer: Incidence and Mortality Follow-up of the Italian Randomized Controlled Trial (SCORE)
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Nereo Segnan,
Carlo Senore,
Luigina A. Bonelli,
Bruno Andreoni,
Orietta Giliani,
Adriano Giacomin,
Marco Zappa,
Mauro Risio,
Stefania Sciallero,
Luigi Bisanti,
Cristiano Crosta,
Arrigo Arrigoni,
Paola Armaroli
et al.
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S-15
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