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Cover 1
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Miscellaneous
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page OFC
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| This Month in Gastroenterology |
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This Month in Gastroenterology
02 July 2009
Recognition and treatment of Helicobacter pylori infection and use of nonsteroidal anti-inflammatory drugs (NSAIDs) as causes of peptic ulcer have led to a substantial decrease in the incidence of pep...
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Jan Tack,
John M. Carethers
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Discussion
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pages 397-400
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| Gastroenterology and Hepatology News |
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Diet–Exercise Program Reduces Functional Decline in Long-Term Cancer Survivors
22 June 2009
A home-based diet and exercise program reduced the rate of functional decline among older, overweight, long-term survivors of colorectal, breast, and prostate cancers, according to a study in the May ...
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Les Lang
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Full-length article
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page 401
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Pancreatic Enzyme Replacement Product, Pancrelipase, Gains Federal Approval
22 June 2009
The US Food and Drug Administration (FDA) announced on May 7, 2009, the approval of pancrelipase (Creon), a pancreatic enzyme replacement product designed to help patients with cystic fibrosis or exoc...
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Les Lang
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Full-length article
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pages 401-402
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Burnout Rate Is Lower Among Academic Physicians When Time Is Spent on Meaningful Work
22 June 2009
Faculty physicians at academic medical centers may be less likely to experience burnout if they spend at least 1 day per week on the aspect of their work that is most meaningful to them, according to ...
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Les Lang
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Full-length article
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page 402
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NIH Liver Injury Network Expands
22 June 2009
Drug-induced liver injury (DILI) is the leading cause of acute liver failure in the United States and is becoming an increasingly important health concern as more people take prescription, over-the-co...
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Les Lang
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Full-length article
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page 403
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| Mini-Review and Perspective |
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Concepts in Familial Colorectal Cancer: Where Do We Stand and What Is the Future?
22 June 2009
Colorectal cancer (CRC) has one of the most familial components of all human cancers. However, only a small fraction—up to 3%–5%—arise in the setting of the highly penetrant inherited syndromes, namel...
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Antoni Castells,
Sergi Castellví–Bel,
Francesc Balaguer
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Full-length article
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pages 404-409
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| Comment From the Editors |
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Gastroenterology Year in Review
24 June 2009
As the AGA Institute's flagship journal, Gastroenterology leads the field of digestive, liver, and pancreatic disease, providing readers with a broad mix of original clinical and basic research, trans...
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Erin C. Dubnansky,
Anil K. Rustgi
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Editorial
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pages 410-411
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| Editorials |
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Article Title |
Author(s) |
Type |
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Do Diabetes Drugs Modify the Risk of Pancreatic Cancer?
29 June 2009
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Yu–Xiao Yang
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Editorial
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pages 412-415
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Infection, Inflammation, and Homeostasis in Inflammatory Bowel Disease
29 June 2009
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Lyn Sue Kahng
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Editorial
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pages 415-418
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Microbiome Analysis in the Esophagus
29 June 2009
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Sebastian Suerbaum
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Editorial
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pages 419-421
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New Insights into the Role of Hedgehog Signaling in Gastrointestinal Development and Cancer
29 June 2009
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Byeong–Moo Kim,
Michael Y. Choi
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Editorial
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pages 422-424
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In the Zone: How a Hepatocyte Knows Where It Is
02 July 2009
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Klaus H. Kaestner
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Editorial
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pages 425-427
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Gumming Up the Works: DNA Polymers as HCV Entry Inhibitors
29 June 2009
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Natalie A. Counihan,
Brett D. Lindenbach
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Editorial
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pages 427-430
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| Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
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Common Cause of Chronic Diarrhea Not to Be Forgotten
19 March 2009
Question: A 26-year-old accounting student consulted his primary care physician with upper abdominal discomfort. Born in Malawi, he had been resident in the United Kingdom for 2 years. Examination and...
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Salil Singh,
Georgina Howarth,
Simon Campbell
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Discussion
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page 431
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An Unusual Post Gastrectomy Complication
23 February 2009
Question: A 62-year-old man presented with repeated episodes of epigastric pain arising about 2 hours postprandially, and radiating to the back. There were associated symptoms of nausea, vomiting, per...
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Ine Moors,
Harald Peeters,
Wim Ceelen
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Discussion
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page 432
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Bleeding Rectal Varices: Trouble Upstream?
02 July 2009
Question: A 47-year-old man presented with a stuttering course of painless hematochezia for the past 3–4 months. He was admitted after passing about 2 pints of blood with a formed stool. He reported p...
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Christopher S. Kleeman,
Timothy P. Maroney,
David A. Sass
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Discussion
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page 433
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| Electronic Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
Type |
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A Small Submucosal Tumor in Antrum
29 June 2009
Question: A 60-year-old woman was referred from local clinics because of incidental finding of 1 gastric submucosal tumor via upper gastrointestinal endoscopy during a health examination. She had no s...
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Chih-Yu Chien,
Peng-Jen Chen,
Nieh Hsin
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Discussion
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pages e1-e2
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Atypical Cause of Abdominal Pain
29 June 2009
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Joanna Ying-Jiin Chen,
Chien-Kan Chen,
Kuo-Ming Chang
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Discussion
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pages e3-e4
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An Unusual Cause of a Pancreatic Head Tumor
29 June 2009
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Brian K.P. Goh,
Sittampalam M. Kesavan,
Wai-Keong Wong
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Discussion
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pages e5-e6
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Endoscopic Ultrasound in CBD Stone
29 June 2009
Question: A 40-year-old woman complained of recurrent episodes of right upper quadrant pain. Liver function tests were normal. An abdominal ultrasound revealed a dilated common bile duct (CBD). Comput...
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Malay Sharma,
Amit Pathak,
Yasha Sharma
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Discussion
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pages e7-e8
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| Imaging and Advanced Technology |
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Article Title |
Author(s) |
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The Future Is Wireless: Advances in Wireless Diagnostic and Therapeutic Technologies in Gastroenterology
22 June 2009
Arthur C. Clarke in his essay “Hazards of Prophecy: The Failure of Imagination,” proposed 3 laws of prediction. The first law is that, “When a distinguished but elderly scientist states that something...
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Virender K. Sharma
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Full-length article
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pages 434-439
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Argon Plasma Coagulation of Cervical Heterotopic Gastric Mucosa as an Alternative Treatment for Globus Sensations
04 May 2009
Background & Aims: Ablation of gastric inlet patches (GIP) in the cervical esophagus by argon plasma coagulation (APC) can alleviate chronic globus sensations in the throat. We investigated the ef...
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Monther Bajbouj,
Valentin Becker,
Florian Eckel,
Stephan Miehlke,
Oliver Pech,
Christian Prinz,
Roland M. Schmid,
Alexander Meining
et al.
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Full-length article
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pages 440-444
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Delayed Radionucleotide Gastric Emptying Studies Predict Morbidity in Diabetics With Symptoms of Gastroparesis
04 May 2009
Background & Aims: The aim of this study was to evaluate the prognostic value of gastric emptying studies on the morbidity associated with diabetic gastroparesis. Methods: This was a parallel coho...
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Brian Hyett,
Fernando J. Martinez,
Brian M. Gill,
Shilpa Mehra,
Anthony Lembo,
Ciaran P. Kelly,
Daniel A. Leffler
et al.
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Full-length article
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pages 445-452
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Microtome-Free 3-Dimensional Confocal Imaging Method for Visualization of Mouse Intestine With Subcellular-Level Resolution
18 May 2009
Background & Aims: The intrinsic opacity of mouse intestinal tissue prevents its evaluation by high-resolution, in-depth optical microscopy. Instead, intestinal tissue is usually sectioned to expo...
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Ya–Yuan Fu,
Chi–Wen Lin,
Grigori Enikolopov,
Eric Sibley,
Ann–Shyn Chiang,
Shiue–Cheng Tang
et al.
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Full-length article
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pages 453-465
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| Reviews in Basic and Clinical Gastroenterology |
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Article Title |
Author(s) |
Type |
Pages |
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Stem Cells and Liver Regeneration
25 May 2009
One of the defining features of the liver is the capacity to maintain a constant size despite injury. Although the precise molecular signals involved in the maintenance of liver size are not completel...
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Andrew W. Duncan,
Craig Dorrell,
Markus Grompe
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Review article
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pages 466-481
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| Clinical-Alimentary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Antidiabetic Therapies Affect Risk of Pancreatic Cancer
17 April 2009
Background & Aims: Antidiabetic drugs have been found to have various effects on cancer in experimental systems and in epidemiologic studies, although the association between these therapeutics an...
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Donghui Li,
Sai–Ching J. Yeung,
Manal M. Hassan,
Marina Konopleva,
James L. Abbruzzese
et al.
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Full-length article
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pages 482-488
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Increased Colorectal Cancer Incidence in Obligate Carriers of Heterozygous Mutations in MUTYH
27 April 2009
Background & Aims: MUTYH-associated polyposis (MAP) is an autosomal recessive disorder caused by mutations in the MUTYH gene. Patients with MAP are at extremely high risk of colorectal cancer, but...
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Natalie Jones,
Stefanie Vogt,
Maartje Nielsen,
Daria Christian,
Petra A. Wark,
Diana Eccles,
Emma Edwards,
D. Gareth Evans,
Eamonn R. Maher,
Hans F. Vasen,
Frederik J. Hes,
Stefan Aretz,
Julian R. Sampson
et al.
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Full-length article
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pages 489-494.e1
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Increased Short- and Long-Term Risk of Inflammatory Bowel Disease After Salmonella or Campylobacter Gastroenteritis
09 April 2009
Background & Aims: Various commensal enteric and potentially pathogenic bacteria may be involved in the pathogenesis of inflammatory bowel diseases (IBD). We compared the risk of IBD between a coh...
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Kim O. Gradel,
Hans L. Nielsen,
Henrik C. Schønheyder,
Tove Ejlertsen,
Brian Kristensen,
Henrik Nielsen
et al.
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Full-length article
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pages 495-501
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Time Trends in Therapies and Outcomes for Adult Inflammatory Bowel Disease, Northern California, 1998–2005
14 May 2009
Background & Aims: The management of inflammatory bowel disease (IBD) has become increasingly complicated, and it is unknown whether poor outcomes (prolonged steroid use, hospitalizations, and sur...
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Lisa J. Herrinton,
Liyan Liu,
Bruce Fireman,
James D. Lewis,
James E. Allison,
Nicole Flowers,
Susan Hutfless,
Fernando S. Velayos,
Oren Abramson,
Andrea Altschuler,
Geraldine S. Perry
et al.
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Full-length article
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pages 502-511
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Fecal Incontinence in US Adults: Epidemiology and Risk Factors
04 May 2009
Background & Aims: The study aims were to estimate the prevalence of different types and frequencies of fecal incontinence (FI), describe demographic factors, and identify risk factors. Methods: T...
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William E. Whitehead,
Lori Borrud,
Patricia S. Goode,
Susan Meikle,
Elizabeth R. Mueller,
Ashok Tuteja,
Alison Weidner,
Milena Weinstein,
Wen Ye,
Pelvic Floor Disorders Network
et al.
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Full-length article
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pages 512-517.e2
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Direct-to-Consumer and Physician Promotion of Tegaserod Correlated With Physician Visits, Diagnoses, and Prescriptions
14 May 2009
Background & Aims: Direct-to-consumer advertisement (DTCA) and physician promotion of drugs can influence patient and physician behaviors. We sought to determine the relationship between promotion...
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Spencer D. Dorn,
Joel F. Farley,
Richard A. Hansen,
Nilay D. Shah,
Robert S. Sandler
et al.
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Full-length article
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pages 518-524.e2
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High Incidence of Mortality and Recurrent Bleeding in Patients With Helicobacter pylori–Negative Idiopathic Bleeding Ulcers
14 May 2009
Background & Aims: The long-term prognosis of peptic ulcers associated with neither Helicobacter pylori nor nonsteroidal anti-inflammatory drugs (NSAIDs) is unknown. Methods: This 7-year prospecti...
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Grace Lai–Hung Wong,
Vincent Wai–Sun Wong,
Yawen Chan,
Jessica Yuet–Ling Ching,
Kim Au,
Aric Josun Hui,
Larry Hin Lai,
Dorothy Kai–Lai Chow,
Danny Ka–Fai Siu,
Yan–Ni Lui,
Justin Che–Yuen Wu,
Ka–Fai To,
Lawrence Cheung–Tsui Hung,
Henry Lik–Yuen Chan,
Joseph Jao–Yiu Sung,
Francis Ka–Leung Chan
et al.
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Full-length article
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pages 525-531
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| Clinical Advances in Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Prospective Study of the Long-Term Effects of Bariatric Surgery on Liver Injury in Patients Without Advanced Disease
01 May 2009
Background & Aims: Severe obesity is implicated in development of nonalcoholic fatty liver disease (NAFLD). Bariatric surgery induces weight loss and increases survival time of obese patients, but...
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Philippe Mathurin,
Antoine Hollebecque,
Laurent Arnalsteen,
David Buob,
Emmanuelle Leteurtre,
Robert Caiazzo,
Marie Pigeyre,
Hélène Verkindt,
Sébastien Dharancy,
Alexandre Louvet,
Monique Romon,
François Pattou
et al.
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Full-length article
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pages 532-540
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Infection in Patients With Severe Alcoholic Hepatitis Treated With Steroids: Early Response to Therapy Is the Key Factor
14 May 2009
Background & Aims: In severe (Maddrey score ≥32) alcoholic hepatitis (AH), infection is classically viewed as a contraindication for corticosteroids, although specific data are lacking. This study...
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Alexandre Louvet,
Faustine Wartel,
Hélène Castel,
Sébastien Dharancy,
Antoine Hollebecque,
Valérie Canva–Delcambre,
Pierre Deltenre,
Philippe Mathurin
et al.
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Full-length article
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pages 541-548
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| Clinical-Liver, Pancreas, and Biliary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
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Weight-Related Effects on Disease Progression in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis Trial
14 May 2009
Background & Aims: With the limited efficacy of current therapy for chronic hepatitis C, modifiable risk factors for liver disease progression are important to identify. Because obesity is associa...
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James E. Everhart,
Anna S. Lok,
Hae–Young Kim,
Timothy R. Morgan,
Karen L. Lindsay,
Raymond T. Chung,
Herbert L. Bonkovsky,
Marc G. Ghany,
HALT–C Trial Group
et al.
|
Full-length article
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pages 549-557
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Expression of S100A2 Calcium-Binding Protein Predicts Response to Pancreatectomy for Pancreatic Cancer
20 April 2009
Background & Aims: Current methods of preoperative staging and predicting outcome following pancreatectomy for pancreatic cancer (PC) are inadequate. We evaluated the utility of multiple biomarker...
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Andrew V. Biankin,
James G. Kench,
Emily K. Colvin,
Davendra Segara,
Christopher J. Scarlett,
Nam Q. Nguyen,
David K. Chang,
Adrienne L. Morey,
C.–Soon Lee,
Mark Pinese,
Samuel C.L. Kuo,
Johana M. Susanto,
Peter H. Cosman,
Geoffrey J. Lindeman,
Jane E. Visvader,
Tuan V. Nguyen,
Neil D. Merrett,
Janindra Warusavitarne,
Elizabeth A. Musgrove,
Susan M. Henshall,
Robert L. Sutherland,
NSW Pancreatic Cancer Network
et al.
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Full-length article
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pages 558-568.e11
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| Basic-Alimentary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
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Endogenous and Exogenous Hydrogen Sulfide Promotes Resolution of Colitis in Rats
17 April 2009
Background & Aims: Hydrogen sulfide (H2S) is an endogenous gaseous mediator of mucosal defense with antiinflammatory effects that promote ulcer healing. The effects of H2S during the pathogenesis ...
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John L. Wallace,
Linda Vong,
Webb McKnight,
Michael Dicay,
Gary R. Martin
et al.
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Full-length article
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pages 569-578.e1
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Salmonella Induces Flagellin- and MyD88-Dependent Migration of Bacteria-Capturing Dendritic Cells Into the Gut Lumen
17 April 2009
Background & Aims: Intestinal dendritic cells (DCs) sample bacteria, such as Salmonella, by extending cellular processes into the lumen to capture bacteria and shuttle them across the epithelium; ...
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Juan L. Arques,
Isabelle Hautefort,
Kamal Ivory,
Eugenio Bertelli,
Marì Regoli,
Simon Clare,
Jay C.D. Hinton,
Claudio Nicoletti
et al.
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Full-length article
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pages 579-587.e2
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Inflammation and Intestinal Metaplasia of the Distal Esophagus Are Associated With Alterations in the Microbiome
27 April 2009
Background & Aims: Gastroesophageal reflux causes inflammation and intestinal metaplasia and its downstream sequelum adenocarcinoma in the distal esophagus. The incidence of esophageal adenocarcin...
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Liying Yang,
Xiaohua Lu,
Carlos W. Nossa,
Fritz Francois,
Richard M. Peek,
Zhiheng Pei
et al.
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Full-length article
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pages 588-597
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Release of Endogenous Opioids From Duodenal Enteroendocrine Cells Requires Trpm5
09 March 2009
Background & Aims: Enteroendocrine cells, the largest and most diverse population of mammalian endocrine cells, comprise a number of different cell types in the gut mucosa that produce, store, and...
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Zaza Kokrashvili,
Deniliz Rodriguez,
Valeriya Yevshayeva,
Hang Zhou,
Robert F. Margolskee,
Bedrich Mosinger
et al.
|
Full-length article
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pages 598-606.e2
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Synaptic Scaffolding Molecule Binds to and Regulates Vasoactive Intestinal Polypeptide Type-1 Receptor in Epithelial Cells
04 February 2009
Background & Aims: Vasoactive intestinal polypeptide (VIP) is a principal regulator of fluid and electrolyte secretion in the gastrointestinal system. The VIP type-1 receptor (VPAC1), a class II G...
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Heon Yung Gee,
Young Woong Kim,
Min Jae Jo,
Wan Namkung,
Joo Young Kim,
Hyun Woo Park,
Kyung Sik Kim,
Hoguen Kim,
Akemichi Baba,
Jinhee Yang,
Eunjoon Kim,
Kyung Hwan Kim,
Min Goo Lee
et al.
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Full-length article
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pages 607-617.e4
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Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning
14 May 2009
Background & Aims: Hedgehog signaling is critical in gastrointestinal patterning. Mice deficient in Hedgehog signaling exhibit abnormalities that mirror deformities seen in the human VACTERL (vert...
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Åsa Kolterud,
Ann S. Grosse,
William J. Zacharias,
Katherine D. Walton,
Katherine E. Kretovich,
Blair B. Madison,
Meghna Waghray,
Jennifer E. Ferris,
Chunbo Hu,
Juanita L. Merchant,
Andrzej A. Dlugosz,
Andreas H. Kottmann,
Deborah L. Gumucio
et al.
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Full-length article
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pages 618-628
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Reduced Level of Smoothened Suppresses Intestinal Tumorigenesis by Down-Regulation of Wnt Signaling
08 May 2009
Background & Aims: Although the Hedgehog (Hh) pathway regulates development and progression of several types of cancer, its involvement in colon cancer remains unclear. We aimed to clarify the rol...
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Sumimasa Arimura,
Akihiro Matsunaga,
Takanori Kitamura,
Koji Aoki,
Masahiro Aoki,
Makoto M. Taketo
et al.
|
Full-length article
|
pages 629-638
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ITF-2 Is Disrupted via Allelic Loss of Chromosome 18q21, and ITF-2B Expression Is Lost at the Adenoma-Carcinoma Transition
27 April 2009
Background & Aims: The ubiquitously expressed basic helix-loop-helix transcription factor ITF-2B has an important role in differentiation processes, and its transcription is regulated by β-catenin...
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Andreas Herbst,
Guido T. Bommer,
Lydia Kriegl,
Andreas Jung,
Andrea Behrens,
Endy Csanadi,
Markus Gerhard,
Christian Bolz,
Rainer Riesenberg,
Wolfgang Zimmermann,
Wolfgang Dietmaier,
Isabella Wolf,
Thomas Brabletz,
Burkhard Göke,
Frank T. Kolligs
et al.
|
Full-length article
|
pages 639-648.e9
|
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Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism
14 May 2009
Background & Aims: MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression. The tumor suppressor miRNA let-7a has been reported to be inhibited posttranscriptionally in embryonic stem...
|
Sripathi M. Sureban,
Randal May,
Satish Ramalingam,
Dharmalingam Subramaniam,
Gopalan Natarajan,
Shrikant Anant,
Courtney W. Houchen
et al.
|
Full-length article
|
pages 649-659.e2
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| Basic-Liver, Pancreas, and Biliary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
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Convergence of Wnt Signaling on the HNF4α-Driven Transcription in Controlling Liver Zonation
18 May 2009
Background & Aims: In each hepatocyte, the specific repertoire of gene expression is influenced by its exact location along the portocentrovenular axis of the hepatic lobule and provides a reason ...
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Marta Colletti,
Carla Cicchini,
Alice Conigliaro,
Laura Santangelo,
Tonino Alonzi,
Emiliano Pasquini,
Marco Tripodi,
Laura Amicone
et al.
|
Full-length article
|
pages 660-672
|
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Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry
27 April 2009
Background & Aims: Hepatitis C virus (HCV) gains entry into susceptible cells by interacting with cell surface receptor(s). Viral entry is an attractive target for antiviral development because of...
|
Takuya Matsumura,
Zongyi Hu,
Takanobu Kato,
Marlene Dreux,
Yong–Yuan Zhang,
Michio Imamura,
Nobuhiko Hiraga,
Jean–Marc Juteau,
Francois–Loic Cosset,
Kazuaki Chayama,
Andrew Vaillant,
T. Jake Liang
et al.
|
Full-length article
|
pages 673-681
|
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Profile of Tumor Antigen-Specific CD8 T Cells in Patients With Hepatitis B Virus-Related Hepatocellular Carcinoma
27 April 2009
Background & Aims: Tumor and viral antigens are expressed by hepatocellular carcinoma (HCC) in patients with chronic hepatitis B, but little is known about the immunodominance and function of tumo...
|
Adam J. Gehring,
Zi Zong Ho,
Anthony T. Tan,
Myat Oo Aung,
Kang Hoe Lee,
Kai Chah Tan,
Seng Gee Lim,
Antonio Bertoletti
et al.
|
Full-length article
|
pages 682-690
|
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Aberrant Cell Cycle Progression and Endoreplication in Regenerating Livers of Mice That Lack a Single E-Type Cyclin
14 May 2009
Background & Aims: E-cyclins control the transition of quiescent cells into the cell cycle. Two E-cyclins, CcnE1 and CcnE2, have been described, but their specific contributions to cell cycle reen...
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Yulia A. Nevzorova,
Darjus Tschaharganeh,
Nikolaus Gassler,
Yan Geng,
Ralf Weiskirchen,
Piotr Sicinski,
Christian Trautwein,
Christian Liedtke
et al.
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Full-length article
|
pages 691-703.e6
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Bone Marrow Progenitor Cells Repair Rat Hepatic Sinusoidal Endothelial Cells After Liver Injury
18 May 2009
Background & Aims: Damage to hepatic sinusoidal endothelial cells (SECs) initiates sinusoidal obstruction syndrome (SOS), which is most commonly a consequence of myeloablative chemoirradiation or ...
|
Rula Harb,
Guanhua Xie,
Carolyn Lutzko,
Yumei Guo,
Xiangdong Wang,
Colin K. Hill,
Gary C. Kanel,
Laurie D. DeLeve
et al.
|
Full-length article
|
pages 704-712
|
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Kupffer Cells Mediate Leptin-Induced Liver Fibrosis
17 April 2009
Background & Aims: Leptin has profibrogenic effects in liver, although the mechanisms of this process are unclear. We sought to elucidate the direct and indirect effects of leptin on hepatic stell...
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Jianhua Wang,
Isabelle Leclercq,
Joanne M. Brymora,
Ning Xu,
Mehdi Ramezani–Moghadam,
Roslyn M. London,
David Brigstock,
Jacob George
et al.
|
Full-length article
|
pages 713-723.e1
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| Continuing Medical Education (CME) Activities |
| |
Article Title |
Author(s) |
Type |
Pages |
|
|
Continuing Medical Education Exam 1, August 2009
24 June 2009
|
Michael B. Wallace
|
Examination
|
pages 724-725
|
|
|
Continuing Medical Education Exam 2, August 2009
26 June 2009
|
|
Examination
|
pages 725-726
|
| Selected Summaries |
| |
Article Title |
Author(s) |
Type |
Pages |
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Occludin a New HCV Entry Factor: Is the List of Essential Hepatitis C Virus Receptors Complete?
29 June 2009
Ploss A, Evans MJ, Gaysinskaya VA, et al. (Center for the Study of Hepatitis C, The Rockefeller University, New York, New York). Human occludin is a hepatitis C virus entry factor required for infecti...
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Bernd Kronenberger,
Stefan Zeuzem
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Discussion
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pages 727-728
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Gut Permeability in Irritable Bowel Syndrome: More Leaks Add to Slightly Inflamed Bowel Syndrome Conspiracy Theory
29 June 2009
Piche T, Barbara G, Aubert P, et al. (INSERM U 913, Hopital Hotel Dieu, Nantes, France). Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of so...
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Eamonn Quigley
|
Discussion
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pages 728-730
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Chemoprevention in the Lynch Syndrome: What Can We Do?
29 June 2009
Burn J, Bishop DT, Mecklin JP, et al; for the CAPP2 Investigators. (Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, United Kingdom). Effect of aspirin or resistant starch on co...
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Carmen López–Ramos,
Antoni Castells
|
Discussion
|
pages 730-732
|
|
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Gut Permeability and Colitis
29 June 2009
Arieta MC, Madsen K, Doyle J, et al. (Department of Medicine, University of Alberta, Walter C. Mackenzie Health Science Centre, Edmonton, Alberta, Canada). Reducing small intestinal permeability atten...
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Peter Mannon
|
Discussion
|
pages 732-734
|
|
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Targeting Farnesoid X Receptor in Hepatic and Biliary Inflammatory Diseases
29 June 2009
Wang YD, Chen WD, Wang M, et al. (Department of Gene Regulation and Drug Discovery, Beckman Research Institute, City of Hope National Medical Center, Duarte, California). Farnesoid X receptor antagoni...
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Nicolas Chignard,
Raoul Poupon
|
Discussion
|
pages 734-735
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|
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Reply
29 June 2009
We agree with the commentary by Drs Chignard and Poupon, particularly with respect to the point that FXR activation suppresses inducible nitric oxide synthase (iNOS) mRNA level induced by lipopolysacc...
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Yan-Dong Wang,
Wei-Dong Chen,
Wendong Huang
|
Discussion
|
page 736
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