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Cover 1
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Miscellaneous
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page OFC
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| This Month in Gastroenterology |
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This Month in Gastroenterology
01 June 2009
Celiac disease is a well-recognized cause of malabsorptive diarrhea, which responds to a strict, gluten-free diet. The availability of noninvasive, serologic testing has revealed a higher prevalence o...
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Jan Tack,
John M. Carethers
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Discussion
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pages 1-3
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| Gastroenterology and Hepatology News |
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The Institute of Medicine Calls for Voluntary and Regulatory Measures to Reduce Conflicts of Interest
18 May 2009
New voluntary and regulatory measures can strengthen protections against financial conflicts of interest in medicine without hindering patient care or the advancement of medical knowledge, claims a ne...
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Les Lang
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Full-length article
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page 4
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Genome-Wide Association Study Points to Colorectal Cancer Culprit
18 May 2009
Several common genetic markers have been found to be associated with colorectal cancer. In a study published online in Genome Research, scientists have now identified a common genetic variation associ...
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Les Lang
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Full-length article
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pages 4-5
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Transplanted Hepatocytes Function in Older Animals But Do Not Proliferate as Much as in Younger Ones
18 May 2009
Hepatocyte transplantation has been successful in a number of animal models, raising hopes that their use could overcome the shortage of donor livers and surgical issues, but the procedure has not bee...
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Les Lang
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Full-length article
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page 5
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Jeremy Robin Jass, GI Pathologist
18 May 2009
Jeremy Robin Jass, Professor of Gastrointestinal Pathology at St. Mark's Hospital and Imperial College in London, UK, died on November 30, 2008. The author of >300 original papers and many books, J...
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Les Lang
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Full-length article
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pages 5-6
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| Mini-Reviews and Perspectives |
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Computed Tomographic Colonography: Current Perspectives and Future Directions
18 May 2009
Computed tomographic (CT) colonography, also known as virtual colonoscopy or CT colography, is capable of detecting colon polyps and cancers. It is emerging rapidly and has gained great momentum over ...
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Don C. Rockey
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Full-length article
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pages 7-14
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OLFM4 Is a Robust Marker for Stem Cells in Human Intestine and Marks a Subset of Colorectal Cancer Cells
18 May 2009
The epithelium of the small intestine and colon is the most rapidly self-renewing tissue in mammals. Proliferative cells are confined to crypts, and differentiated cell types predominantly occupy the ...
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Laurens G. van der Flier,
Andrea Haegebarth,
Daniel E. Stange,
Marc van de Wetering,
Hans Clevers
et al.
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Full-length article
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pages 15-17
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| Comment From the Editor |
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Intestinal Lipids as Signaling Molecules
01 June 2009
Obesity is a major problem in modern society, in part because of overconsumption of energy-dense and fatty foods. Most adults consume 60–150 g/d of fat, containing mainly triglycerides (>90%). Dige...
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Rexford S. Ahima
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Editorial
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pages 18-19
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| Editorials |
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Evidence That Proton-Pump Inhibitor Therapy Induces the Symptoms it Is Used to Treat
01 June 2009
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Kenneth E.L. McColl,
Derek Gillen
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Editorial
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pages 20-22
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New Epidemiologic Evidence on Functional Dyspepsia Subgroups and Their Relationship to Psychosocial Dysfunction
01 June 2009
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Lukas Van Oudenhove,
Jan Tack
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Editorial
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pages 23-26
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α-Fetoprotein for Hepatocellular Carcinoma Diagnosis: The Demise of a Brilliant Star
01 June 2009
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Alejandro Forner,
María Reig,
Jordi Bruix
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Editorial
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pages 26-29
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Paneth Cell Development, Differentiation, and Function: New Molecular Cues
04 June 2009
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Thaddeus S. Stappenbeck
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Editorial
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pages 30-33
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Intersection of Transforming Growth Factor-β and Wnt Signaling Pathways in Colorectal Cancer and Metastasis
01 June 2009
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John M. Carethers
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Editorial
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pages 33-36
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Fucose Is on the TRAIL of Colon Cancer
01 June 2009
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Robert S. Haltiwanger
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Editorial
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pages 36-39
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| Clinical Challenges and Images in GI |
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A Rare Cause of Obstructive Jaundice
08 June 2009
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Ahmed Abdel Samie,
Rui Sun,
Lorenz Theilmann
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Discussion
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page 40
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A Metamorphic Lesion
03 June 2009
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Carla Rolanda,
Raquel Gonçalves,
Guilherme Macedo
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Discussion
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page 41
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Unremitting Upper GI Bleeding from a Duodenal Mass
01 June 2009
Question: A 68-year-old Caucasian man was admitted with a 1-week history of hematochezia and hemoptysis. At an outside community hospital he was found to have a hemoglobin of 9.6 g/dL and hematocrit o...
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Koushik K. Das,
Vasudha Dhar
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Discussion
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page 42
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| Electronic Clinical Challenges and Images in GI |
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A Case With Duodenal Bleeding
01 June 2009
Question: A 52-year-old woman was admitted to our hospital in October 2007 because of a 5-day history of dizziness and shortness of breath. Upon admission, physical examination showed no remarkable ab...
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Jen-Wei Chou,
Wen-Hsin Huang,
Hsueh-Chou Lai
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Discussion
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pages e1-e2
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A “Crescent-in-doughnut” Lesion at Right Lower Quadrant Abdomen
01 June 2009
Question: A 51-year-old man had been robust until 2 days before admission when he had right lower quadrant abdominal dull pain accompanied with bloody stool passage. There was no weight loss, fever, n...
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Chen–Shuan Chung,
Ming–Yang Wang,
Hsiu–Po Wang
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Discussion
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pages e3-e4
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Working Out the Bug in the Accordion
05 June 2009
Question: A clinically stable, 46-year-old man presented with a 1-week history of nausea and nonbloody diarrhea. He had previous rectal cancer treated with a low anterior resection, radiation, and che...
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Natasha Chandok,
Patrick S. Kamath
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Discussion
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pages e5-e6
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| Imaging and Advanced Technology |
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Contrast-Enhanced Ultrasonographic Evaluation of Inflammatory Activity in Crohn's Disease
06 May 2009
Background & Aims: We sought to test the diagnostic accuracy of ultrasound (US), color Doppler US (CD-US), and contrast-enhanced US (CE-US) in the evaluation of inflammatory activity in patients w...
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Vincenzo Migaleddu,
Antonio M. Scanu,
Emilio Quaia,
Paolo Cossu Rocca,
Maria Pina Dore,
Domenico Scanu,
Lorenza Azzali,
Giuseppe Virgilio
et al.
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Full-length article
 
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pages 43-52
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Bioengineered Internal Anal Sphincter Derived From Isolated Human Internal Anal Sphincter Smooth Muscle Cells
31 March 2009
Background & Aims: The internal anal sphincter (IAS) is a specialized circular smooth muscle that maintains rectoanal continence. In vitro models are needed to study the pathophysiology of human I...
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Sita Somara,
Robert R. Gilmont,
Robert G. Dennis,
Khalil N. Bitar
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Full-length article
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pages 53-61
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| Reviews in Basic and Clinical Gastroenterology |
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Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies
31 March 2009
The study of liver development has significantly contributed to developmental concepts about morphogenesis and differentiation of other organs. Knowledge of the mechanisms that regulate hepatic epithe...
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Frédéric P. Lemaigre
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Review article
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pages 62-79
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| Clinical-Alimentary Tract |
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Proton-Pump Inhibitor Therapy Induces Acid-Related Symptoms in Healthy Volunteers After Withdrawal of Therapy
13 April 2009
Background & Aims: Rebound acid hypersecretion (RAHS) has been demonstrated after 8 weeks of treatment with a proton-pump inhibitor (PPI). If RAHS induces acid-related symptoms, this might lead to...
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Christina Reimer,
Bo Søndergaard,
Linda Hilsted,
Peter Bytzer
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Full-length article
 
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pages 80-87.e1
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Increased Prevalence and Mortality in Undiagnosed Celiac Disease
13 April 2009
Background & Aims: The historical prevalence and long-term outcome of undiagnosed celiac disease (CD) are unknown. We investigated the long-term outcome of undiagnosed CD and whether the prevalenc...
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Alberto Rubio–Tapia,
Robert A. Kyle,
Edward L. Kaplan,
Dwight R. Johnson,
William Page,
Frederick Erdtmann,
Tricia L. Brantner,
W. Ray Kim,
Tara K. Phelps,
Brian D. Lahr,
Alan R. Zinsmeister,
L. Joseph Melton,
Joseph A. Murray
et al.
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Full-length article
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pages 88-93
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Anxiety Is Associated With Uninvestigated and Functional Dyspepsia (Rome III Criteria) in a Swedish Population-Based Study
31 March 2009
Background & Aims: The Rome III criteria for functional dyspepsia have been changed to include 2 distinct syndromes: postprandial distress syndrome and epigastric pain syndrome. We investigated ri...
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Pertti Aro,
Nicholas J. Talley,
Jukka Ronkainen,
Tom Storskrubb,
Michael Vieth,
Sven–Erik Johansson,
Elisabeth Bolling–Sternevald,
Lars Agréus
et al.
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Full-length article
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pages 94-100
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Frequency of Mitochondrial Defects in Patients With Chronic Intestinal Pseudo-Obstruction
03 April 2009
Background & Aims: Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder caused by intestinal dysmotility and characterized by chronic symptoms suggesting bowel obstruction in the absenc...
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Aurélien Amiot,
Maya Tchikviladzé,
Francisca Joly,
Abdelhamid Slama,
Dominique Cazals Hatem,
Claude Jardel,
Bernard Messing,
Anne Lombès
et al.
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Full-length article
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pages 101-109
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| Clinical Advances in Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma
10 April 2009
Background & Aims: α-Fetoprotein (AFP) is widely used as a surveillance test for hepatocellular carcinoma (HCC) among patients with cirrhosis. Des-γ carboxy-prothrombin (DCP) and lectin-bound AFP ...
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Jorge A. Marrero,
Ziding Feng,
Yinghui Wang,
Mindie H. Nguyen,
Alex S. Befeler,
Lewis R. Roberts,
K. Rajender Reddy,
Denise Harnois,
Josep M. Llovet,
Daniel Normolle,
Jackie Dalhgren,
David Chia,
Anna S. Lok,
Paul D. Wagner,
Sudhir Srivastava,
Myron Schwartz
et al.
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Full-length article
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pages 110-118
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| Clinical-Liver, Pancreas, and Biliary Tract |
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Type |
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Acute Hemodynamic Response to β-Blockers and Prediction of Long-term Outcome in Primary Prophylaxis of Variceal Bleeding
03 April 2009
Background & Aims: Studies of variceal bleeding have shown that a hemodynamic response to treatment of portal hypertension is appropriate when the hepatic venous pressure gradient (HVPG) decreases...
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Càndid Villanueva,
Carles Aracil,
Alan Colomo,
Virginia Hernández–Gea,
Josep M. López–Balaguer,
Cristina Alvarez–Urturi,
Xavier Torras,
Joaquim Balanzó,
Carlos Guarner
et al.
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Full-length article
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pages 119-128
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Early Changes in Blood Urea Nitrogen Predict Mortality in Acute Pancreatitis
03 April 2009
Background & Aims: Routine laboratory tests that reflect intravascular volume status can play an important role in the early assessment of acute pancreatitis (AP). The objective of this study was ...
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Bechien U. Wu,
Richard S. Johannes,
Xiaowu Sun,
Darwin L. Conwell,
Peter A. Banks
et al.
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Full-length article
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pages 129-135
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| Basic-Alimentary Tract |
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Article Title |
Author(s) |
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Colony Stimulating Factor-1 Dependence of Paneth Cell Development in the Mouse Small Intestine
19 March 2009
Background & Aims: Paneth cells (PCs) secrete defensins and antimicrobial enzymes that contribute to innate immunity against pathogen infections within the mucosa of the small intestine. We examin...
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Duy Huynh,
Xu–Ming Dai,
Sayan Nandi,
Sally Lightowler,
Melanie Trivett,
Chee–Kai Chan,
Ivan Bertoncello,
Robert G. Ramsay,
E. Richard Stanley
et al.
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Full-length article
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pages 136-144.e3
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Notch Signaling Promotes the Generation of EphrinB1-Positive Intestinal Epithelial Cells
31 March 2009
Background & Aims: The intestinal epithelium consists of EphB2-positive proliferative basal cryptic cells and EphrinB1-positive, postmitotic differentiated cells. We investigated the effects of No...
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Bon–Kyoung Koo,
Hyoung–Soo Lim,
Hee Jin Chang,
Mi–Jeong Yoon,
Yongwook Choi,
Myung–Phil Kong,
Cheol–Hee Kim,
Jin–Man Kim,
Jae–Gahb Park,
Young–Yun Kong
et al.
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Full-length article
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pages 145-155.e3
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The Symplekin/ZONAB Complex Inhibits Intestinal Cell Differentiation by the Repression of AML1/Runx1
31 March 2009
Background & Aims: Symplekin is a ubiquitously expressed protein involved in RNA polyadenylation and transcriptional regulation that localizes at tight junctions in epithelial cells. The associati...
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Michael Buchert,
Charbel Darido,
Ebba Lagerqvist,
Anna Sedello,
Chantal Cazevieille,
Frank Buchholz,
Jean–Francois Bourgaux,
Julie Pannequin,
Dominique Joubert,
Frédéric Hollande
et al.
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Full-length article
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pages 156-164.e3
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A Colorectal Cancer Expression Profile That Includes Transforming Growth Factor β Inhibitor BAMBI Predicts Metastatic Potential
31 March 2009
Background & Aims: Much is known about the genes and mutations that cause colorectal cancer (CRC), yet only a few have been associated with CRC metastasis. We performed expression-profiling experi...
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Johannes Fritzmann,
Markus Morkel,
Daniel Besser,
Jan Budczies,
Frauke Kosel,
Felix H. Brembeck,
Ulrike Stein,
Iduna Fichtner,
Peter M. Schlag,
Walter Birchmeier
et al.
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Full-length article
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pages 165-175
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Frequent Inactivation of Axon Guidance Molecule RGMA in Human Colon Cancer Through Genetic and Epigenetic Mechanisms
19 March 2009
Background & Aims: Repulsive guidance molecule member A (RGMA) is a glycosylphosphatidylinositol-anchored glycoprotein and axon guidance molecule that signals through its receptor, neogenin (NEO1)...
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Vivian S.W. Li,
Siu Tsan Yuen,
Tsun Leung Chan,
Helen H.N. Yan,
Wai Lun Law,
Bonnie H.Y. Yeung,
Annie S.Y. Chan,
Wai Yin Tsui,
Samuel So,
Xin Chen,
Suet Yi Leung
et al.
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Full-length article
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pages 176-187
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Deficiency of GMDS Leads to Escape from NK Cell-Mediated Tumor Surveillance Through Modulation of TRAIL Signaling
09 April 2009
Background & Aims: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes apoptosis in cancer cells, but not normal cells, and is critically involved in tumor rejection through n...
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Kenta Moriwaki,
Katsuhisa Noda,
Yoichi Furukawa,
Kenji Ohshima,
Airi Uchiyama,
Tsutomu Nakagawa,
Naoyuki Taniguchi,
Yataro Daigo,
Yusuke Nakamura,
Norio Hayashi,
Eiji Miyoshi
et al.
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Full-length article
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pages 188-198.e2
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Prohibitin Is a Novel Regulator of Antioxidant Response That Attenuates Colonic Inflammation in Mice
26 March 2009
Background & Aims: Increased free radicals and/or impaired antioxidant defenses have been shown to play a pathogenetic role in human and animal models of inflammatory bowel disease. Our previous s...
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Arianne L. Theiss,
Matam Vijay–Kumar,
Tracy S. Obertone,
Dean P. Jones,
Jason M. Hansen,
Andrew T. Gewirtz,
Didier Merlin,
Shanthi V. Sitaraman
et al.
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Full-length article
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pages 199-208.e6
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Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency
19 March 2009
Background & Aims: Goblet cells (GC) facilitate mucosal protection and epithelial barrier repair, yet the innate immune mechanisms that selectively drive GC functions have not been defined. The ai...
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Daniel K. Podolsky,
Guido Gerken,
Annette Eyking,
Elke Cario
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Full-length article
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pages 209-220
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Heparin-Binding EGF-Like Growth Factor Increases Intestinal Microvascular Blood Flow in Necrotizing Enterocolitis
09 April 2009
Background & Aims: Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates. Although the exact etiology remains unknown, decreased intestinal blood flow is believ...
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Xiaoyi Yu,
Andrei Radulescu,
Nicholas Zorko,
Gail E. Besner
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Full-length article
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pages 221-230
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Delineation of the Chemomechanosensory Regulation of Gastrin Secretion Using Pure Rodent G Cells
16 January 2009
Background & Aims: Gastrin is a key regulator of gastric acid secretion. We aimed to isolate pure G cells to identify the mechanistic basis of luminal- and strain-mediated regulation. Methods: Usi...
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Mark Kidd,
Øyvind Hauso,
Ignat Drozdov,
Bjorn I. Gustafsson,
Irvin M. Modlin
et al.
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Full-length article
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pages 231-241.e10
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Laminin γ2 Mediates Wnt5a-Induced Invasion of Gastric Cancer Cells
11 February 2009
Background & Aims: Wnt5a expression stimulates in vitro migration and invasion of cultured gastric cancer cells by an unknown mechanism and is also correlated with aggressiveness of gastric tumors...
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Hideki Yamamoto,
Yasuhiko Kitadai,
Hideki Yamamoto,
Naohide Oue,
Hideki Ohdan,
Wataru Yasui,
Akira Kikuchi
et al.
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Full-length article
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pages 242-252.e6
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Negative Mood Affects Brain Processing of Visceral Sensation
23 February 2009
Background & Aims: A link between negative emotional state and abnormal visceral sensation has been frequently reported. However, the influence of negative emotion on brain processing of painful v...
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Steven J. Coen,
Lidia Yágüez,
Qasim Aziz,
Martina T. Mitterschiffthaler,
Mick Brammer,
Steven C.R. Williams,
Lloyd J. Gregory
et al.
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Full-length article
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pages 253-261.e2
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Mechanisms of Neural Response to Gastrointestinal Nutritive Stimuli: The Gut-Brain Axis
26 February 2009
Background & Aims: The gut-brain axis, which transmits nutrient information from the gastrointestinal tract to the brain, is important for the detection of dietary nutrients. We used functional ma...
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Tomokazu Tsurugizawa,
Akira Uematsu,
Eiji Nakamura,
Mai Hasumura,
Mariko Hirota,
Takashi Kondoh,
Hisayuki Uneyama,
Kunio Torii
et al.
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Full-length article
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pages 262-273
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Identification of Medium/High-Threshold Extrinsic Mechanosensitive Afferent Nerves to the Gastrointestinal Tract
06 March 2009
Background & Aims: Large distentions reliably evoke sensation from the noninflamed, nonischemic bowel, but the specialized afferent axonal structures responsible have not been morphologically iden...
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Xingyun Song,
Bao Nan Chen,
Vladimir P. Zagorodnyuk,
Penny A. Lynn,
L. Ashley Blackshaw,
David Grundy,
Alan M. Brunsden,
Marcello Costa,
Simon J.H. Brookes
et al.
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Full-length article
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pages 274-284.e1
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| Basic-Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Hepatitis C Virus and Disrupted Interferon Signaling Promote Lymphoproliferation via Type II CD95 and Interleukins
10 April 2009
Background & Aims: The molecular mechanisms of lymphoproliferation associated with the disruption of interferon (IFN) signaling and chronic hepatitis C virus (HCV) infection are poorly understood....
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Keigo Machida,
Kyoko Tsukiyama–Kohara,
Satoshi Sekiguch,
Eiji Seike,
Shigenobu Tóne,
Yukiko Hayashi,
Yoshimi Tobita,
Yuri Kasama,
Masumi Shimizu,
Hidemi Takahashi,
Chyoji Taya,
Hiromichi Yonekawa,
Nobuyuki Tanaka,
Michinori Kohara
et al.
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Full-length article
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pages 285-296.e11
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c-Met Confers Protection Against Chronic Liver Tissue Damage and Fibrosis Progression After Bile Duct Ligation in Mice
06 February 2009
Background & Aims: The hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (c-Met) system is an essential inducer of hepatocyte growth and proliferation. Although a fundamental...
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Arne Giebeler,
Mark V. Boekschoten,
Christian Klein,
Malgorzata Borowiak,
Carmen Birchmeier,
Nikolaus Gassler,
Hermann E. Wasmuth,
Michael Müller,
Christian Trautwein,
Konrad L. Streetz
et al.
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Full-length article
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pages 297-308.e4
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Antifibrotic Effects of CXCL9 and Its Receptor CXCR3 in Livers of Mice and Humans
03 April 2009
Background & Aims: Fibrosis is the hallmark of chronic liver diseases, yet many aspects of its mechanism remain to be defined. Chemokines are ubiquitous chemotactic molecules that mediate many acu...
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Hermann E. Wasmuth,
Frank Lammert,
Mirko Moreno Zaldivar,
Ralf Weiskirchen,
Claus Hellerbrand,
David Scholten,
Marie-Luise Berres,
Henning Zimmermann,
Konrad L. Streetz,
Frank Tacke,
Sonja Hillebrandt,
Petra Schmitz,
Hildegard Keppeler,
Thomas Berg,
Edgar Dahl,
Nikolaus Gassler,
Scott L. Friedman,
Christian Trautwein
et al.
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Full-length article
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pages 309-319.e3
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Gut Homing Receptors on CD8 T Cells Are Retinoic Acid Dependent and Not Maintained by Liver Dendritic or Stellate Cells
23 February 2009
Background & Aims: Lymphocytes primed by intestinal dendritic cells (DC) express the gut-homing receptors CCR9 and α4β7, which recognize CCL25 and mucosal addressin cell-adhesion molecule-1 in the...
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Bertus Eksteen,
J. Rodrigo Mora,
Emma L. Haughton,
Neil C. Henderson,
Laura Lee–Turner,
Eduardo J. Villablanca,
Stuart M. Curbishley,
Alex I. Aspinall,
Ulrich H. von Andrian,
David H. Adams
et al.
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Full-length article
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pages 320-329
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Y-Box Binding Protein-1 Down-Regulates Expression of Carbamoyl Phosphate Synthetase-I by Suppressing CCAAT Enhancer-Binding Protein-Alpha Function in Mice
09 March 2009
Background & Aims: Carbamoyl phosphate synthetase-I (CPS1) is a key enzyme in the urea cycle and patients with defects in the function or expression of CPS1 suffer from hyperammonemia. CPS1 is exp...
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Yen–Rong Chen,
Keisuke Sekine,
Koji Nakamura,
Hiroyuki Yanai,
Minoru Tanaka,
Atsushi Miyajima
et al.
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Full-length article
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pages 330-340
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Cannabinoid Type 1 Receptor Antagonism Delays Ascites Formation in Rats With Cirrhosis
16 January 2009
Background & Aims: Endocannabinoids contribute to hemodynamic abnormalities of cirrhosis. Whether this favors renal sodium retention and ascites formation is unknown. We determined whether cannabi...
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Marco Domenicali,
Paolo Caraceni,
Ferdinando Giannone,
Anna Maria Pertosa,
Alessandro Principe,
Andrea Zambruni,
Franco Trevisani,
Tiziano Croci,
Mauro Bernardi
et al.
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Full-length article
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pages 341-349
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Impaired Autolysosome Formation Correlates With Lamp-2 Depletion: Role of Apoptosis, Autophagy, and Necrosis in Pancreatitis
10 April 2009
Background & Aims: Acute pancreatitis constitutes a life-threatening condition in which pancreatic acinar cells undergo massive cell death. We investigated the incidence of apoptosis, autophagy, a...
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Franco Fortunato,
Heinrich Bürgers,
Frank Bergmann,
Peter Rieger,
Markus W. Büchler,
Guido Kroemer,
Jens Werner
et al.
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Full-length article
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pages 350-360.e5
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E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex
10 April 2009
Background & Aims: Early metastasis is a hallmark of pancreatic ductal adenocarcinoma and responsible for >90% of pancreatic cancer death. Because little is known about the biology and genetics...
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Johannes von Burstin,
Stefan Eser,
Mariel C. Paul,
Barbara Seidler,
Martina Brandl,
Marlena Messer,
Alexander von Werder,
Annegret Schmidt,
Jörg Mages,
Philipp Pagel,
Angelika Schnieke,
Roland M. Schmid,
Günter Schneider,
Dieter Saur
et al.
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Full-length article
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pages 361-371.e5
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| Continuing Medical Education (CME) Activities |
| |
Article Title |
Author(s) |
Type |
Pages |
|
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Continuing Medical Education Exam 1, July 2009
01 June 2009
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Michael B. Wallace
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Examination
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pages 372-373
|
|
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Continuing Medical Education Exam 2, July 2009
01 June 2009
|
|
Examination
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pages 373-374
|
| Selected Summaries |
| |
Article Title |
Author(s) |
Type |
Pages |
|
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To Expand or Not to Expand the Criteria for Hepatocellular Carcinoma Transplantation: Is Downstaging the Answer?
01 June 2009
Yao FY, Kerlan RK Jr., Hirose R, et al. (Department of Medicine, University of California, San Francisco, San Francisco, California). Excellent outcome following down-staging of hepatocellular carcino...
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Alejandro Forner,
Jordi Bruix
|
Discussion
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pages 375-376
|
|
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Reply
01 June 2009
We thank Alejandro Forner and Jordi Bruix for their review of our study on downstaging of patients with hepatocellular carcinoma (HCC). Patients who undergo liver transplantation for HCC according to ...
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Francis Y. Yao,
John P. Roberts
|
Discussion
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page 377
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|
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“Adjuvant” Therapy after Endoscopic Mucosal Resection of Early Gastric Cancer
01 June 2009
Fukase K, Kato M, Kikuchi S, et al. (Department of Gastroenterology, Yamagata Prefectural Central Hospital, Yamagata, Japan). Effect of eradication of Helicobacter pylori on incidence of metachronous ...
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James J. Farrell
|
Discussion
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pages 377-379
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|
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A New Answer to an Old Question: Azathioprine Withdrawal in Quiescent Crohn's Disease
01 June 2009
Treton X, Bouhnik Y, Mary J, et al. (Hopital Beaujon, Clichy, France). Azathioprine withdrawal in patients with Crohn's disease maintained on prolonged remission: a high risk of relapse. Clin Gastroen...
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Justin L. Sewell,
Uma Mahadevan
|
Discussion
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pages 379-381
|
|
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Intestinal Microbiota Gives a Nod to the Hygiene Hypothesis in Type 1 Diabetes
01 June 2009
Wen L, Ley RE, Volchkov PY, et al. (Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut). Innate immunity and intestinal microbiota in the development of Type 1 diabet...
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Rodrigue Dessein,
Laurent Peyrin-Biroulet,
Mathias Chamaillard
|
Discussion
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pages 381-383
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