| This Month in Gastroenterology |
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This Month in Gastroenterology
05 January 2009
A large proportion of patients with Crohn's disease require intestinal resection for stricturing or perforating disease. Most patients develop recurrence of Crohn's disease over time, usually proximal...
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Jan Tack,
John M. Carethers
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Discussion
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pages 369-372
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| Gastroenterology and Hepatology News |
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Article Title |
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Vaccine Against Rotavirus Lowers Hospitalizations and Emergency Visits
24 December 2008
A vaccine against rotavirus, the leading cause of diarrhea in infants, has led to a dramatic drop in hospitalizations and emergency department visits since it came on the market 2 years ago, doctors r...
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Les Lang
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Full-length article
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page 373
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Liver Transplantation Allocation System Shows Improvement in Racial, But Not Gender, Disparities
24 December 2008
After the introduction of a new system in 2002 to determine the allocation of donated livers, African-American patients are no longer less likely to receive a liver transplant, but disparities for wom...
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Les Lang
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Full-length article
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pages 373-374
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New Study Finds Publication Bias Among Trials Submitted to the US Food and Drug Administration
24 December 2008
One fourth of all drug trials submitted in support of new drug applications (NDAs) to the US Food and Drug Administration (FDA) remain unpublished 5 years after the fact, according to new research pub...
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Les Lang
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Full-length article
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page 374
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Article Announces New Current Procedural Terminology Coding-Related Issues for 2009
24 December 2008
Current Procedural Terminology (CPT) is a listing of descriptive terms and identifying codes for reporting medical services and procedures. First developed and published in 1966 and currently maintain...
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Les Lang
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Full-length article
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pages 374-375
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| Mini-Reviews and Perspectives |
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Type |
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Burden of Digestive Diseases in the United States Part I: Overall and Upper Gastrointestinal Diseases
05 January 2009
Introduction to Series: Digestive, liver, and pancreatic diseases have a far-reaching medical, economic, social, and political impact on society in the United States and worldwide. We believe it is im...
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James E. Everhart,
Constance E. Ruhl
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Full-length article
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pages 376-386
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| Comment From the Editor |
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Article Title |
Author(s) |
Type |
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Liver Fibrosis: Challenges of the New Era
22 December 2008
As hepatologists are well aware, the care of patients with fibrosis is entering a new era. Over the last few decades, the tools available for clinical care, the intellectual framework we use to unders...
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Rebecca G. Wells
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Editorial
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pages 387-388
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| Editorials |
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Article Title |
Author(s) |
Type |
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Hepatitis B: A “GLOBAL” Health Challenge
24 December 2008
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Robert J. Fontana
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Editorial
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pages 389-392
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Treatment of HBV/HCV Coinfection: Releasing the Enemy Within
22 December 2008
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Stuart C. Gordon,
Kenneth E. Sherman
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Editorial
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pages 393-396
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Exposed: The Genetic Underpinnings of Ulcerative Colitis Relative to Crohn's Disease
05 January 2009
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Steven R. Brant
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Editorial
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pages 396-399
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Is Inflammatory Bowel Disease a Vascular Disease? Targeting Angiogenesis Improves Chronic Inflammation in Inflammatory Bowel Disease
29 December 2008
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David G. Binion,
Parvaneh Rafiee
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Editorial
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pages 400-403
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| Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
Type |
Pages |
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Clinical Challenges and Images in GI
05 January 2009
Question: A 63-year-old man with no significant medical history presented with obscure abdominal discomfort. He underwent computed tomography (), which revealed a mass in the pelvic cavity. The mass w...
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Satoru Takayama,
Masaki Sakamoto,
Hiromitsu Takeyama
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Discussion
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page 404
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Clinical Challenges and Images in GI
29 December 2008
Question: An 18-year-old immigrant from Africa was referred to the GI clinic for intermittent diarrhea. He reported a seven month history of intermittent, nonradiating, diffuse, crampy abdominal pain ...
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Meenakshi Bewtra,
Ashlie N. Burkart,
Faten N. Aberra
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Discussion
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page 405
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Clinical Challenges and Images in GI
22 December 2008
Question: A 44-year-old woman (172 cm tall, weighing 77 kg) first presented with ascites and decompensated liver cirrhosis in 2006. Her history was significant for heavy alcohol consumption. Serologic...
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Christian P. Strassburg,
Frank Lehner,
Hans H. Kreipe
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Discussion
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page 406
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| Electronic Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
Type |
Pages |
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Electronic Clinical Challenges and Images in GI
22 December 2008
Question: A 72-year-old woman presented to the emergency department with new-onset abdominal pain and nausea of 1 day's duration. The abdominal pain was sharp and worse on the right side of her abdome...
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Lourdes G. Bahamonde,
Igor Grosman,
David E. Bernstein
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Discussion
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pages e1-e2
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Electronic Clinical Challenges and Images in GI
05 January 2009
Question: A 59-year-old woman was admitted as an emergency with a 12-month history of weight loss and diarrhea in the absence of anorexia. In 1999, she had a barium meal for dyspepsia demonstrating a ...
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Ian Tanswell,
Helen Steed
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Discussion
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pages e3-e4
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Electronic Clinical Challenges and Images in GI
29 December 2008
Question: A 32-year-old woman was admitted with a 1-week history of constant, midline abdominal pain radiating to her back that worsened postprandially. She also reported a 1-week history of nausea, b...
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Jamie B. Walters,
Vinay Sundaram,
Dhiraj Yadav
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Discussion
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pages e5-e6
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| Imaging and Advanced Technology |
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Article Title |
Author(s) |
Type |
Pages |
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Molecular Imaging of the Pancreas in Small Animal Models
22 December 2008
Recent advances in several imaging modalities have improved noninvasive assessment of the pancreas in preclinical animal models and have enabled sequential studies in the same animal, permitting dynam...
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John Virostko,
Alvin C. Powers
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Full-length article
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pages 407-409
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Narrow-Band Versus White-Light High Definition Television Endoscopic Imaging for Screening Colonoscopy: A Prospective Randomized Trial
16 October 2008
Background & Aims: Narrow-band imaging (NBI) has been implemented in gastrointestinal endoscopy to improve the contrast of endoluminal pathologic structures, one of the aims being to increase colo...
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Andreas Adler,
Jens Aschenbeck,
Timur Yenerim,
Michael Mayr,
Alireza Aminalai,
Rolf Drossel,
Andreas Schröder,
Matthias Scheel,
Bertram Wiedenmann,
Thomas Rösch
et al.
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Full-length article
 
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pages 410-416.e1
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A Magnetic Resonance Spectroscopy Study of Brain Glutamate in a Model of Plasticity in Human Pharyngeal Motor Cortex
11 November 2008
Background & Aims: Coordinated delivery of peripheral and cortical stimuli (paired associative stimulation [PAS]) has been shown to induce plasticity in limb motor cortex, however, its application...
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Salil Singh,
Satish Mistry,
Samantha Jefferson,
Karen Davies,
John Rothwell,
Stephen Williams,
Shaheen Hamdy
et al.
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Full-length article
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pages 417-424
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| Reviews in Basic and Clinical Gastroenterology |
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Article Title |
Author(s) |
Type |
Pages |
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Roles of Infection, Inflammation, and the Immune System in Cholesterol Gallstone Formation
24 December 2008
Cholesterol gallstone formation is a complex process mediated by genetic and environmental factors. Until recently, the role of the immune system in the pathogenesis of cholesterol gallstones was not ...
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Kirk J. Maurer,
Martin C. Carey,
James G. Fox
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Review article
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pages 425-440
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| Clinical-Alimentary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Infliximab Prevents Crohn's Disease Recurrence After Ileal Resection
03 November 2008
Background & Aims: Crohn's disease commonly recurs after intestinal resection. We evaluated whether the administration of infliximab after resective intestinal surgery for Crohn's disease reduces ...
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Miguel Regueiro,
Wolfgang Schraut,
Leonard Baidoo,
Kevin E. Kip,
Antonia R. Sepulveda,
Marilyn Pesci,
Janet Harrison,
Scott E. Plevy
et al.
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Full-length article
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pages 441-450.e1
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Risk of Cervical Abnormalities in Women With Inflammatory Bowel Disease: A Population-Based Nested Case-Control Study
16 October 2008
Background & Aims: We evaluated the risk of cervical abnormalities in women with inflammatory bowel disease (IBD) in a population-based, nested, case-control study. Methods: Cases with abnormal Pa...
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Harminder Singh,
Alain A. Demers,
Zoann Nugent,
Salaheddin M. Mahmud,
Erich V. Kliewer,
Charles N. Bernstein
et al.
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Full-length article
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pages 451-458
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High Detection Rates of Colorectal Neoplasia by Stool DNA Testing With a Novel Digital Melt Curve Assay
16 October 2008
Background & Aims: Current stool DNA tests identify about half of individuals with colorectal cancers and miss most individuals with advanced adenomas. We developed a digital melt curve (DMC) assa...
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Hongzhi Zou,
William R. Taylor,
Jonathan J. Harrington,
Fareeda Taher Nazer Hussain,
Xiaoming Cao,
Charles L. Loprinzi,
Theodore R. Levine,
Douglas K. Rex,
Dennis Ahnen,
Kandice L. Knigge,
Peter Lance,
Xuan Jiang,
David I. Smith,
David A. Ahlquist
et al.
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Full-length article
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pages 459-470
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Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis
03 November 2008
Background & Aims: Biallelic mutations in the base excision DNA repair gene MUTYH lead to MUTYH-associated polyposis (MAP) and predisposition to colorectal cancer (CRC). Functional studies have de...
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Maartje Nielsen,
Mirjam C. Joerink - van de Beld,
Natalie Jones,
Stefanie Vogt,
Carli M. Tops,
Hans F.A. Vasen,
Julian R. Sampson,
Stefan Aretz,
Frederik J. Hes
et al.
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Full-length article
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pages 471-476
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| Clinical Advances in Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Elevated Serum Alanine Aminotransferase and γ-Glutamyltransferase and Mortality in the United States Population
30 October 2008
Background & Aims: Elevated serum alanine aminotransferase (ALT) and γ-glutamyltransferase (GGT) activities are markers of liver injury, but may also be associated with other diseases and death. I...
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Constance E. Ruhl,
James E. Everhart
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Full-length article
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pages 477-485.e11
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2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B
24 October 2008
Background & Aims: The GLOBE trial has compared the efficacy and safety of telbivudine versus lamivudine treatment over 2 years in patients with chronic hepatitis B. Methods: Hepatitis B e antigen...
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Yun–Fan Liaw,
Edward Gane,
Nancy Leung,
Stefan Zeuzem,
Yuming Wang,
Ching Lung Lai,
E. Jenny Heathcote,
Michael Manns,
Natalie Bzowej,
Junqi Niu,
Steven–Huy Han,
Seong Gyu Hwang,
Yilmaz Cakaloglu,
Myron J. Tong,
George Papatheodoridis,
Yagang Chen,
Nathaniel A. Brown,
Efsevia Albanis,
Karin Galil,
Nikolai V. Naoumov,
The GLOBE Study Group
et al.
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Full-length article
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pages 486-495
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| Clinical-Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Peginterferon Alfa-2a Plus Ribavirin for the Treatment of Dual Chronic Infection With Hepatitis B and C Viruses
30 October 2008
Background & Aims: Dual chronic infection with hepatitis C virus (HCV) and hepatitis B virus (HBV) is common in areas endemic for either virus. Combination therapy with ribavirin and pegylated int...
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Chun–Jen Liu,
Wan–Long Chuang,
Chuan–Mo Lee,
Ming–Lung Yu,
Sheng–Nan Lu,
Shun–Sheng Wu,
Li–Ying Liao,
Chi–Ling Chen,
Hsing–Tao Kuo,
You–Chen Chao,
Shui–Yi Tung,
Sien–Sing Yang,
Jia–Horng Kao,
Chen–Hua Liu,
Wei–Wen Su,
Chih–Lin Lin,
Yung–Ming Jeng,
Pei–Jer Chen,
Ding–Shinn Chen
et al.
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Full-length article
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pages 496-504.e3
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Predictive Factors for Early HBeAg Seroconversion in Acute Exacerbation of Patients With HBeAg-Positive Chronic Hepatitis B
27 November 2008
Background & Aims: This study aimed to identify the predictors for early hepatitis B e antigen (HBeAg) seroconversion following acute exacerbation (AE) in patients with HBeAg-positive chronic hepa...
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Hyoung Su Kim,
Ha Jung Kim,
Woon Geon Shin,
Kyung Ho Kim,
Jin Heon Lee,
Hak Yang Kim,
Myoung Kuk Jang
et al.
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Full-length article
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pages 505-512
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Reduced Pancreatic Volume and β-Cell Area in Patients With Chronic Pancreatitis
07 November 2008
Background & Aims: Chronic pancreatitis (CP) often leads to the development of diabetes. To understand better this pathogenic mechanism, we investigated whether islet cell area and pancreatic volu...
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Henning Schrader,
Bjoern A. Menge,
Simone Schneider,
Orlin Belyaev,
Andrea Tannapfel,
Waldemar Uhl,
Wolfgang E. Schmidt,
Juris J. Meier
et al.
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Full-length article
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pages 513-522
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| Basic-Alimentary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Investigation of Crohn's Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship
28 October 2008
Background & Aims: Identifying shared and disease-specific susceptibility loci for Crohn's disease (CD) and ulcerative colitis (UC) would help define the biologic relationship between the inflamma...
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Carl A. Anderson,
Dunecan C.O. Massey,
Jeffrey C. Barrett,
Natalie J. Prescott,
Mark Tremelling,
Sheila A. Fisher,
Rhian Gwilliam,
Jemima Jacob,
Elaine R. Nimmo,
Hazel Drummond,
Charlie W. Lees,
Clive M. Onnie,
Catherine Hanson,
Katarzyna Blaszczyk,
Radhi Ravindrarajah,
Sarah Hunt,
Dhiraj Varma,
Naomi Hammond,
Gregory Lewis,
Heather Attlesey,
Nick Watkins,
Willem Ouwehand,
David Strachan,
Wendy McArdle,
Cathryn M. Lewis,
The Wellcome Trust Case Control Consortium,
Alan Lobo,
Jeremy Sanderson,
Derek P. Jewell,
Panos Deloukas,
John C. Mansfield,
Christopher G. Mathew,
Jack Satsangi,
Miles Parkes
et al.
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Full-length article
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pages 523-529.e3
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Glucocorticoid-Induced Leucine Zipper Is Protective in Th1-Mediated Models of Colitis
26 September 2008
Background & Aims: Inflammatory bowel diseases are relatively common diseases of the gastrointestinal tract. The relative therapeutic efficacy of glucocorticoids used in inflammatory bowel disease...
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Lorenza Cannarile,
Salvatore Cuzzocrea,
Luca Santucci,
Massimiliano Agostini,
Emanuela Mazzon,
Emanuela Esposito,
Carmelo Muià,
Maddalena Coppo,
Rosanna Di Paola,
Carlo Riccardi
et al.
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Full-length article
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pages 530-541
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Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia
11 November 2008
Background & Aims: The clonality of colitis-associated neoplasia has not been fully determined. One previous report showed polyclonal origins with subsequent monoclonal outgrowth. We aimed to asse...
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Simon J. Leedham,
Trevor A. Graham,
Dahmane Oukrif,
Stuart A.C. McDonald,
Manuel Rodriguez–Justo,
Rebecca F. Harrison,
Neil A. Shepherd,
Marco R. Novelli,
Janusz A.Z. Jankowski,
Nicholas A. Wright
et al.
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Full-length article
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pages 542-550.e6
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Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis
07 November 2008
Background & Aims: Inflammatory bowel disease (IBD) is a multifactorial disease thought to be caused by alterations in epithelial function, innate and adaptive immunity, and luminal microbiota. Th...
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Liping Su,
Le Shen,
Daniel R. Clayburgh,
Sam C. Nalle,
Erika A. Sullivan,
Jon B. Meddings,
Clara Abraham,
Jerrold R. Turner
et al.
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Full-length article
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pages 551-563
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Dietary Histidine Ameliorates Murine Colitis by Inhibition of Proinflammatory Cytokine Production From Macrophages
06 October 2008
Background & Aims: Elemental diet (ED) is effective for human Crohn's disease (CD). Although some of this effectiveness may be due to its low antigenic load and low fat content, the mechanisms rem...
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Ayatoshi Andou,
Tadakazu Hisamatsu,
Susumu Okamoto,
Hiroshi Chinen,
Nobuhiko Kamada,
Taku Kobayashi,
Masaki Hashimoto,
Tomohisa Okutsu,
Kazutaka Shimbo,
Tomoko Takeda,
Hideki Matsumoto,
Atsushi Sato,
Hiroshi Ohtsu,
Manabu Suzuki,
Toshifumi Hibi
et al.
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Full-length article
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pages 564-574.e2
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Endothelial Caveolin-1 Regulates Pathologic Angiogenesis in a Mouse Model of Colitis
11 November 2008
Background & Aims: Increased vascular density has been associated with progression of human inflammatory bowel diseases (IBDs) and animal models of colitis. Pathologic angiogenesis in chronically ...
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John H. Chidlow,
Joshua J.M. Greer,
Christoph Anthoni,
Pascal Bernatchez,
Carlos Fernadez–Hernando,
Megan Bruce,
Maisoun Abdelbaqi,
Deepti Shukla,
D. Neil Granger,
William C. Sessa,
Christopher G. Kevil
et al.
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Full-length article
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pages 575-584.e2
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VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis
06 October 2008
Background & Aims: Vascular endothelial growth factor A (VEGF-A) mediates angiogenesis and might also have a role in inflammation and immunity. We examined whether VEGF-A signaling has a role in i...
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Franco Scaldaferri,
Stefania Vetrano,
Miquel Sans,
Vincenzo Arena,
Giuseppe Straface,
Egidio Stigliano,
Alessandro Repici,
Andreas Sturm,
Alberto Malesci,
Julian Panes,
Seppo Yla–Herttuala,
Claudio Fiocchi,
Silvio Danese
et al.
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Full-length article
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pages 585-595.e5
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Transgenic Expression of VEGF in Intestinal Epithelium Drives Mesenchymal Cell Interactions and Epithelial Neoplasia
28 October 2008
Background & Aims: Vascular endothelial growth factor (VEGF) is expressed robustly in human colon neoplasia and is a major new “rational” target of therapy for cancers of the colon and other organ...
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Amelie Boquoi,
Rodrigo Jover,
Tina Chen,
Marieke Pennings,
Greg H. Enders
et al.
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Full-length article
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pages 596-606.e4
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Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia
28 October 2008
Background & Aims: The surface of the intestinal mucosa is particularly prone to hypoxia-induced inflammation. Previous studies implicated signaling via extracellular adenosine in endogenous atten...
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Julio C. Morote–Garcia,
Peter Rosenberger,
Nicole M.I. Nivillac,
Imogen R. Coe,
Holger K. Eltzschig
et al.
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Full-length article
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pages 607-618
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Inhibition of p38 Mitogen-Activated Protein Kinase Pathway as Prophylaxis of Postoperative Ileus in Mice
10 October 2008
Background & Aims: Postoperative ileus, an iatrogenic complication of abdominal surgery, is mediated by severe inflammation of the tunica muscularis. Macrophages that reside in the muscularis have...
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Sven Wehner,
Stefan Straesser,
Tim O. Vilz,
Dimitrios Pantelis,
Thais Sielecki,
Vidal F. de la Cruz,
Andreas Hirner,
Joerg C. Kalff
et al.
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Full-length article
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pages 619-629
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Changes in the Structure and Function of ICC Networks in ICC Hyperplasia and Gastrointestinal Stromal Tumors
28 October 2008
Background & Aims: Gastrointestinal stromal tumors (GISTs) express the receptor tyrosine kinase c-kit. Approximately 90% of GISTs have gain-of-function mutations in the Kit gene, which leads to it...
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Joong Goo Kwon,
Sung Jin Hwang,
Grant W. Hennig,
Yulia Bayguinov,
Conor McCann,
Hui Chen,
Ferdinand Rossi,
Peter Besmer,
Kenton M. Sanders,
Sean M. Ward
et al.
|
Full-length article
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pages 630-639
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Methylation of Protocadherin 10, a Novel Tumor Suppressor, Is Associated With Poor Prognosis in Patients With Gastric Cancer
30 October 2008
Background & Aims: By using methylation-sensitive representational difference analysis, we identified protocadherin 10 (PCDH10), a gene that encodes a protocadherin and is silenced in a tumor-spec...
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Jun Yu,
Yuen Y. Cheng,
Qian Tao,
Kin F. Cheung,
Cleo N.Y. Lam,
Hua Geng,
Lin–Wei Tian,
Ying P. Wong,
Joanna H.M. Tong,
Jian–Ming Ying,
Hongchuan Jin,
Ka F. To,
Francis K.L. Chan,
Joseph J.Y. Sung
et al.
|
Full-length article
|
pages 640-651.e1
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| Basic-Liver, Pancreas, and Biliary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
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Direct Cytopathic Effects of Particular Hepatitis B Virus Genotypes in Severe Combined Immunodeficiency Transgenic With Urokinase-Type Plasminogen Activator Mouse With Human Hepatocytes
30 October 2008
Background & Aims: Little is known about the direct cytopathic effect of hepatitis B virus (HBV) and its association with particular viral genotypes or genetic mutations. We investigate HBV genoty...
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Masaya Sugiyama,
Yasuhito Tanaka,
Fuat Kurbanov,
Isao Maruyama,
Takashi Shimada,
Satoru Takahashi,
Tomoyuki Shirai,
Keisuke Hino,
Isao Sakaida,
Masashi Mizokami
et al.
|
Full-length article
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pages 652-662.e3
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Tissue Inhibitor of Metalloproteinase 3 Deficiency Causes Hepatic Steatosis and Adipose Tissue Inflammation in Mice
07 November 2008
Background & Aims: Obesity-driven, low-grade inflammation affects systemic metabolic function and can lead to insulin resistance, hepatic steatosis, and atherosclerosis. Decreased expression of ti...
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Rossella Menghini,
Stefano Menini,
Roberta Amoruso,
Loredana Fiorentino,
Viviana Casagrande,
Valeria Marzano,
Federica Tornei,
Pierfrancesco Bertucci,
Carla Iacobini,
Matteo Serino,
Ottavia Porzio,
Marta L. Hribal,
Franco Folli,
Rama Khokha,
Andrea Urbani,
Renato Lauro,
Giuseppe Pugliese,
Massimo Federici
et al.
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Full-length article
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pages 663-672.e4
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Effective Treatment of Unconjugated Hyperbilirubinemia With Oral Bile Salts in Gunn Rats
07 November 2008
Background & Aims: We tested the hypothesis that oral administration of bile salts, which are known to increase the biliary excretion of unconjugated bilirubin (UCB), decreases unconjugated hyperb...
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Frans J.C. Cuperus,
Anja M. Hafkamp,
Rick Havinga,
Libor Vitek,
Jaroslav Zelenka,
Claudio Tiribelli,
J. Donald Ostrow,
Henkjan J. Verkade
et al.
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Full-length article
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pages 673-682.e1
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MicroRNA-18a Prevents Estrogen Receptor-α Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells
28 October 2008
Background & Aims: Men have a higher incidence of hepatocellular carcinoma (HCC) than women, which is believed to partly be because of protective effects of estrogen. We sought to determine whethe...
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Wan–Hsin Liu,
Shiou–Hwei Yeh,
Cho–Chun Lu,
Sung–Liang Yu,
Hsuan–Yu Chen,
Chien–Yu Lin,
Ding–Shinn Chen,
Pei–Jer Chen
et al.
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Full-length article
|
pages 683-693
|
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T Cell-Derived Lymphotoxin Regulates Liver Regeneration
19 September 2008
Background & Aims: The ability of the liver to regenerate hepatic mass is essential to withstanding liver injury. The process of liver regeneration is tightly regulated by distinct signaling casca...
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Alexei V. Tumanov,
Ekaterina P. Koroleva,
Peter A. Christiansen,
Mehtab A. Khan,
Matthew J. Ruddy,
Byron Burnette,
Salvatore Papa,
Guido Franzoso,
Sergei A. Nedospasov,
Yang–Xin Fu,
Robert A. Anders
et al.
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Full-length article
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pages 694-704.e4
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Liver Myofibroblasts Regulate Infiltration and Positioning of Lymphocytes in Human Liver
16 October 2008
Background & Aims: The recruitment of lymphocytes to tissues via endothelium has been studied extensively but less is known about the signals that direct migration and positioning within tissues. ...
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Andrew P. Holt,
Emma L. Haughton,
Patricia F. Lalor,
Andrew Filer,
Christopher D. Buckley,
David H. Adams
et al.
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Full-length article
|
pages 705-714
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| Continuing Medical Education (CME) Activities |
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Article Title |
Author(s) |
Type |
Pages |
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Continuing Medical Education Exam 1, February 2009
22 December 2008
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Michael B. Wallace
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Examination
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pages 715-716
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|
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Continuing Medical Education Exam 2, February 2009
22 December 2008
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Examination
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pages 716-717
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| Selected Summaries |
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Article Title |
Author(s) |
Type |
Pages |
|
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Scope Early and Often in Ulcerative Colitis and Crohn's Colitis?
22 December 2008
Lutgens M, Vleggaar FP, Schipper M, et al. (Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, The Netherlands). High frequency of early colorectal cancer in inflammato...
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Thomas Ullman,
Mark Lazarev
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Discussion
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pages 718-719
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|
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Reply
22 December 2008
With great interest and appreciation we read the comments made by Drs Ullman and Lazarev. We collected data on all colorectal carcinomas (CRCs) in inflammatory bowel disease (IBD) patients over a peri...
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M.W. Lutgens,
B. Oldenburg,
F.P. Vleggaar
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Discussion
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pages 719-720
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|
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Sequential Therapy for Helicobacter Pylori: A Two for One Deal That's Worth the Extra Effort?
24 December 2008
Jafri NS, Hornung CA, Howden CW. (University of Louisville, Louisville, Kentucky). Meta analysis: sequential therapy appears superior to standard therapy for Helicobacter pylori infection in patients ...
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Jay Luther,
William D. Chey
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Discussion
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pages 720-722
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|
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The Gut Microbiota: A Microbial Arsenal Protecting Us From Infectious and Radiation-Induced Diarrhea
22 December 2008
Sekirov I, Tam NM, Jogova M, et al. (Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, Canada). Antibiotic-induced perturbations of the ...
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Christopher J. Damman,
Christina M. Surawicz
|
Discussion
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pages 722-724
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| Print and Media Reviews |
| |
Article Title |
Author(s) |
Type |
Pages |
|
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Book review
22 December 2008
Students at every level need expert guidance on what information is truly important to know and memorize. But what is the role of a relatively brief paper-based textbook in this age of remarkable comp...
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Nicholas J. Talley
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Book review
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page 725
|
|
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Book review
22 December 2008
This softcover, 207-page laboratory manual that focuses on endoscopic procedures is intended to be a resource to those who are “newly exposed to the endoscopy unit,…for the nurse who is new to the end...
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Jerome D. Waye
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Book review
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pages 725-726
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|
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Book review
22 December 2008
This interesting little book (245 pages) is written in the format of 49 questions, each with its own chapter, related to the care of patients with chronic liver disease. The questions are in the form ...
|
Adrian M. Di Bisceglie
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Book review
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pages 726-727
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| Correspondence |
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Article Title |
Author(s) |
Type |
Pages |
|
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Do We Really Need Alternatives to Polymorphonuclear Cells Counting in Ascitic Fluid?
22 December 2008
We read with interest the paper of Parsi et al and the related editorial about the possibility of using the determination of ascitic fluid lactoferrin (AFLAC) for the diagnosis of spontaneous bacteria...
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Oliviero Riggio,
Chiara Marzano,
Stefania Angeloni,
Manuela Merli
|
Correspondence
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pages 728-729
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|
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Reply
22 December 2008
We appreciate the authors' interest in our paper. The first and the most important step in the development of a rapid bedside test is to find a suitable biomarker. The second step is to determine the ...
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Mansour A. Parsi,
Arthur J. McCullough
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Correspondence
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page 729
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| Correction |
| |
Article Title |
Author(s) |
Type |
Pages |
|
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Correction
12 January 2009
Tsuchiya H, Akechi Y, Ikeda R, et al. Suppressive effects of retinoids on iron-induced oxidative stress in the liver. Gastroenterology 2009;136:341–350.
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Erratum
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page 729
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