| This Month in Gastroenterology |
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This Month in Gastroenterology
10 October 2008
Collagenous colitis is a relatively uncommon cause of chronic diarrhea, with an incidence that is highest in women and increases with age. Although macroscopically normal, microscopic examination of c...
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Jan Tack,
John M. Carethers
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Discussion
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pages 1435-1438
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| Gastroenterology and Hepatology News |
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Author(s) |
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Racial Diversity Among Medical Students May Better Prepare Them for Minority Patient Care
13 October 2008
White medical students who attend schools with greater racial and ethnic diversity among the student body are more likely to rate themselves as highly prepared to care for minority populations, accord...
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Les Lang
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Full-length article
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page 1439
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The FDA Approves DNA Test to Measure Hepatitis B Virus Levels
09 October 2008
The US Food and Drug Administration (FDA) in September approved the first nucleic acid test for hepatitis B virus (HBV) that measures the amount of viral DNA in a patient's blood. The COBAS TaqMan HBV...
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Les Lang
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Full-length article
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pages 1439-1440
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Investigation of Outbreak of Infections Caused by Salmonella Saintpaul
13 October 2008
The US Centers for Disease Control and Prevention (CDC) has been working with state, local and tribal health departments, the Indian Health Service, and the Food and Drug Administration (FDA) to inves...
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Les Lang
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Full-length article
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pages 1440-1441
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FDA Updates Health Information Advisory on Melamine Contamination
10 October 2008
On September 12, 2008, in light of reports from China of melamine-contaminated infant formula, the US Food and Drug Administration (FDA) issued a Health Information Advisory to proactively reassure th...
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Les Lang
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Full-length article
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page 1441
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| Mini-Reviews and Perspectives |
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Author(s) |
Type |
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Current Directions in IBD Therapy: What Goals Are Feasible With Biological Modifiers?
09 October 2008
Crohn's disease is a chronic, progressive, destructive disease, and current treatment strategies are inadequate. The historic treatment goals of induction and maintenance of clinical response and remi...
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William J. Sandborn
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Full-length article
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pages 1442-1447
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| Comment From the Editor |
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Article Title |
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Type |
Pages |
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Gastroenterology Fellowship Training in the 21st Century
09 October 2008
Gastroenterology fellowship training is currently under considerable scrutiny by the American Gastroenterological Association (AGA). Some of this interest stems from potential threats to screening col...
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Timothy C. Wang
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Editorial
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pages 1448-1449
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| Editorials |
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Article Title |
Author(s) |
Type |
Pages |
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Portal Hypertension in Primary Biliary Cirrhosis: A Potentially Reversible Harbinger of Demise
09 October 2008
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Marlyn J. Mayo
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Editorial
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pages 1450-1451
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Using Higher Risk Organs for Liver Transplantation: In Whom and at What Price?
13 October 2008
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Bilal Hameed,
John R. Lake
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Editorial
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pages 1452-1454
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The Demise of the Pencil? New Computer-Assisted Tests for Minimal Hepatic Encephalopathy
13 October 2008
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Satish Iduru,
Kevin D. Mullen
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Editorial
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pages 1455-1456
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Making Sense of HDAC2 Mutations in Colon Cancer
13 October 2008
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John M. Mariadason
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Editorial
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pages 1457-1459
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Ischemia-Driven Expression of CD73 Confers Tissue Protection During Liver Ischemia/Reperfusion
10 October 2008
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Charles C. Caldwell,
Alex B. Lentsch
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Editorial
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pages 1460-1462
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| Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
Type |
Pages |
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Clinical Challenges and Images in GI
13 October 2008
Question: A 68-year old woman was referred to our hospital because of 10 years of refractory dysphagia and odynophagia. She had prior esophagoduodenoscopies (EGD) that revealed gross esophagitis and a...
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Melissa A. Minor,
Hejin Hahn,
John M. Poneros
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Discussion
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page 1463
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Clinical Challenges and Images in GI
13 October 2008
Question: A 25-year-old Japanese woman was admitted to our hospital complaining of abdominal pain. She had had a 2-month history of abdominal distension and exertional dyspnea. The patient's past, fam...
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Naoyuki Yamaguchi,
Hajime Isomoto,
Toshiyuki Nakayama
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Discussion
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page 1464
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Clinical Challenges and Images in GI
13 October 2008
Question: A 60-year-old man presented with acute onset of central abdominal pain radiating into his back. He was tachycardic with severe epigastric tenderness. Computed tomography (CT) confirmed a per...
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Imran Bhatti,
Rachel Melhado,
Paul Leeder,
David Semeraro,
Gillian Tierney
et al.
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Discussion
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page 1465
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| Electronic Clinical Challenges and Images in GI |
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Article Title |
Author(s) |
Type |
Pages |
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Electronic Clinical Challenges and Images in GI
13 October 2008
Question: A 34-year-old man with a history of idiopathic retroperitoneal fibrosis (IRF) and peptic ulcer disease presented to the hospital complaining of several episodes of melena and 1 episode of he...
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Daniel L. Cohen
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Discussion
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pages e1-e2
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Electronic Clinical Challenges and Images in GI
13 October 2008
Question: A 58-year-old man was admitted to the emergency room because of diarrhea, abdominal pain, and fever. Abdominal computed tomography showed a tumor in the sigmoid colon and an abscess adjacent...
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Michel Zabalza,
Faust Feu,
Julià Panés
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Discussion
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pages e3-e4
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Electronic Clinical Challenges and Images in GI
13 October 2008
Question: A 75-year-old woman presented with vomiting. She had a past history of right hip replacement and pyloric ulceration caused by the use of diclofenac, a nonsteroidal anti-inflammatory drug (NS...
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Nicholas C. Bosanko,
Byron Theron,
Pradip Singh
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Discussion
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pages e5-e6
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Electronic Clinical Challenges and Images in GI
13 October 2008
Question: A 69-year-old woman presented to the emergency department with symptoms suggestive of an upper gastrointestinal hemorrhage. For the preceding 4 months, she had suffered from dyspeptic-like s...
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Ian J. Tanswell,
Tadeo Kossakowski,
Gillian Townson
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Discussion
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pages e7-e8
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| Imaging and Advanced Technology |
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Article Title |
Author(s) |
Type |
Pages |
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Transcriptome Profiling Using Next-Generation Sequencing
09 October 2008
High-throughput analysis of transcriptome profiles has become a standard tool in clinical research. The prevailing wisdom holds that one should be able to interpret patterns of gene expression in dise...
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Yan W. Asmann,
Michael B. Wallace,
E. Aubrey Thompson
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Full-length article
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pages 1466-1468
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| Reviews in Basic and Clinical Gastroenterology |
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Author(s) |
Type |
Pages |
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Gastrointestinal Neuroendocrine Tumors: Pancreatic Endocrine Tumors
13 August 2008
Pancreatic endocrine tumors (PETs) have long fascinated clinicians and investigators despite their relative rarity. Their clinical presentation varies depending on whether the tumor is functional or n...
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David C. Metz,
Robert T. Jensen
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Review article
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pages 1469-1492
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| Clinical-Alimentary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Effects of Adalimumab Therapy on Incidence of Hospitalization and Surgery in Crohn's Disease: Results From the CHARM Study
04 August 2008
Background & Aims: We determined the effects of adalimumab maintenance treatment on the risks of hospitalization and surgery in Crohn's disease (CD). Methods: A total of 778 patients with CD were ...
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Brian G. Feagan,
Remo Panaccione,
William J. Sandborn,
Geert R. D'Haens,
Stefan Schreiber,
Paul J. Rutgeerts,
Edward V. Loftus,
Kathleen G. Lomax,
Andrew P. Yu,
Eric Q. Wu,
Jingdong Chao,
Parvez Mulani
et al.
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Full-length article

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pages 1493-1499
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Meta-Analysis of the Placebo Rates of Clinical Relapse and Severe Endoscopic Recurrence in Postoperative Crohn's Disease
04 August 2008
Backgrounds & Aims: The benefit of therapy for prevention of postoperative recurrence of Crohn's disease (CD) is limited. Clinical relapse and severe endoscopic recurrence are the main outcomes in...
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Sara Renna,
Calogero Cammà,
Irene Modesto,
Giuseppe Cabibbo,
Daniela Scimeca,
Giuseppe Civitavecchia,
Filippo Mocciaro,
Ambrogio Orlando,
Marco Enea,
Mario Cottone
et al.
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Full-length article

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pages 1500-1509
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Oral Budesonide for Maintenance Treatment of Collagenous Colitis: A Randomized, Double-Blind, Placebo-Controlled Trial
08 August 2008
Background & Aims: Oral budesonide effectively induces clinical remission in patients with collagenous colitis, a debilitating illness characterized by chronic watery/loose diarrhea, but there is ...
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Stephan Miehlke,
Ahmed Madisch,
Birgit Bethke,
Andrea Morgner,
Eberhard Kuhlisch,
Christine Henker,
Gerfried Vogel,
Matthias Andersen,
Eberhard Meier,
Gustavo Baretton,
Manfred Stolte
et al.
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Full-length article
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pages 1510-1516
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Lower Gastrointestinal Events in a Double-Blind Trial of the Cyclo-Oxygenase-2 Selective Inhibitor Etoricoxib and the Traditional Nonsteroidal Anti-Inflammatory Drug Diclofenac
04 August 2008
Background & Aims: Nonsteroidal anti-inflammatory drugs (NSAIDs) cause lower gastrointestinal (GI) clinical events such as bleeding. Cyclo-oxygenase (COX)-2 selective inhibitors decrease upper GI ...
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Loren Laine,
Sean P. Curtis,
Michael Langman,
Dennis M. Jensen,
Byron Cryer,
Amarjot Kaur,
Christopher P. Cannon
et al.
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Full-length article
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pages 1517-1525
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Achalasia: A New Clinically Relevant Classification by High-Resolution Manometry
24 July 2008
Background & Aims: Although the diagnosis of achalasia hinges on demonstrating impaired esophagogastric junction (EGJ) relaxation and aperistalsis, 3 distinct patterns of aperistalsis are discerna...
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John E. Pandolfino,
Monika A. Kwiatek,
Thomas Nealis,
William Bulsiewicz,
Jennifer Post,
Peter J. Kahrilas
et al.
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Full-length article
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pages 1526-1533
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Causal Relationship of Helicobacter pylori With Iron-Deficiency Anemia or Failure of Iron Supplementation in Children
04 August 2008
Background & Aims: We investigated Helicobacter pylori (H pylori)-infection as a cause of iron deficiency (ID) and iron-deficiency anemia (IDA) or treatment failure of iron supplementation. Method...
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Shafiqul A. Sarker,
Hasan Mahmud,
Lena Davidsson,
Nur H. Alam,
Tahmeed Ahmed,
Nurul Alam,
Mohammed A. Salam,
Christoph Beglinger,
Niklaus Gyr,
George J. Fuchs
et al.
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Full-length article
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pages 1534-1542
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A Novel Noninvasive Genotyping Method of Helicobacter pylori Using Stool Specimens
21 August 2008
Background & Aims: The source(s) of the infection and the route(s) of transmission of Helicobacter pylori have not yet been clarified. This is to introduce a noninvasive protocol allowing molecula...
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Sonja Puz,
Albina Innerhofer,
Michael Ramharter,
Michael Haefner,
Alexander M. Hirschl,
Zsuzsanna Kovách,
Manfred Rotter,
Athanasios Makristathis
et al.
|
Full-length article
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pages 1543-1551
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| Clinical Advances in Liver Pancreas and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Portal Hypertension and Primary Biliary Cirrhosis: Effect of Long-Term Ursodeoxycholic Acid Treatment
24 July 2008
Background & Aims: Portal hypertension can complicate primary biliary cirrhosis, but studies evaluating the direct measurement of the portohepatic gradient (PHG) are rare. The aim of the study was...
|
Pierre–Michel Huet,
Catherine Vincent,
Julie Deslaurier,
Jean Coté,
Shoichi Matsutami,
Robert Boileau,
Jacline Huet–van Kerckvoorde
et al.
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Full-length article
 
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pages 1552-1560
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Silibinin Is a Potent Antiviral Agent in Patients With Chronic Hepatitis C Not Responding to Pegylated Interferon/Ribavirin Therapy
04 August 2008
Background & Aims: Oral Silibinin (SIL) is widely used for treatment of hepatitis C, but its efficacy is unclear. Substantially higher doses can be administered intravenously (IV). Methods: Pedigr...
|
Peter Ferenci,
Thomas–Matthias Scherzer,
Heidrun Kerschner,
Karoline Rutter,
Sandra Beinhardt,
Harald Hofer,
Maximilian Schöniger–Hekele,
Heidemarie Holzmann,
Petra Steindl–Munda
et al.
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Full-length article
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pages 1561-1567
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| Clinical-Liver, Pancreas, and Biliary Tract |
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Article Title |
Author(s) |
Type |
Pages |
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Impact of the Model for End-Stage Liver Disease Allocation Policy on the Use of High-Risk Organs for Liver Transplantation
Background & Aims: Although priority for liver transplantation is determined by the model for end-stage liver disease (MELD) score, the quality of organs used is subject to physician discretion. W...
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Michael L. Volk,
Anna S.F. Lok,
Shawn J. Pelletier,
Peter A. Ubel,
Rodney A. Hayward
et al.
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Full-length article
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pages 1568-1574
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Re-weighting the Model for End-Stage Liver Disease Score Components
15 August 2008
Background & Aims: Liver transplant candidates with mild hepatic synthetic dysfunction and marked renal insufficiency may have higher Model for End-Stage Liver Disease (MELD) scores than candidate...
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Pratima Sharma,
Douglas E. Schaubel,
Camelia S. Sima,
Robert M. Merion,
Anna S.F. Lok
et al.
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Full-length article
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pages 1575-1581
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Computerized Psychometric Testing in Minimal Encephalopathy and Modulation by Nitrogen Challenge and Liver Transplant
27 June 2008
Background & Aims: A lack of standardized tests was cited by hepatologists for not testing for minimal hepatic encephalopathy. We therefore compared paper and pencil neuropsychologic tests with a ...
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Hanan Mardini,
Brian K. Saxby,
Christopher O. Record
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Full-length article
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pages 1582-1590
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Inhibitory Control Test for the Diagnosis of Minimal Hepatic Encephalopathy
24 July 2008
Background & Aims: Minimal hepatic encephalopathy (MHE) is difficult to diagnose. The Inhibitory Control Test (ICT) measures response inhibition and has diagnosed MHE with 90% sensitivity and spec...
|
Jasmohan S. Bajaj,
Muhammad Hafeezullah,
Jose Franco,
Rajiv R. Varma,
Raymond G. Hoffmann,
Joshua F. Knox,
Darrell Hischke,
Thomas A. Hammeke,
Steven D. Pinkerton,
Kia Saeian
et al.
|
Full-length article

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pages 1591-1600.e1
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| Basic-Alimentary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
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Focal Activities and Re-Entrant Propagations as Mechanisms of Gastric Tachyarrhythmias
24 July 2008
Background & Aims: Gastric arrhythmias occur in humans and experimental animals either spontaneously or induced by drugs or diseases. However, there is no information regarding the origin or the p...
|
Wim J.E.P. Lammers,
Luc Ver Donck,
Betty Stephen,
Dirk Smets,
Jan A.J. Schuurkes
et al.
|
Full-length article
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pages 1601-1611
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A Transient Breach in the Epithelial Barrier Leads to Regulatory T-Cell Generation and Resistance to Experimental Colitis
04 August 2008
Background & Aims: Previous studies have indicated that a defective epithelial barrier leads to inflammation of the underlying lamina propria. Nevertheless, it is likely that physiologic breaks in...
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Monica Boirivant,
Antonello Amendola,
Alessia Butera,
Massimo Sanchez,
Lili Xu,
Mariarosaria Marinaro,
Atsushi Kitani,
Claudia Di Giacinto,
Warren Strober,
Ivan J. Fuss
et al.
|
Full-length article
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pages 1612-1623.e5
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MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α
04 August 2008
Background & Aims: Chronic inflammatory bowel diseases such as ulcerative colitis (UC) are associated with differential expression of genes involved in inflammation and tissue remodeling. MicroRNA...
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Feng Wu,
Michelle Zikusoka,
Anil Trindade,
Themistocles Dassopoulos,
Mary L. Harris,
Theodore M. Bayless,
Steven R. Brant,
Shukti Chakravarti,
John H. Kwon
et al.
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Full-length article
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pages 1624-1635.e24
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Circadian Clock-Controlled Intestinal Expression of the Multidrug-Resistance Gene mdr1a in Mice
04 August 2008
Background & Aims: P-glycoprotein, the product of the multidrug resistance (mdr) gene, functions as a xenobiotic transporter contributing to the intestinal barrier. Although intestinal expression ...
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Yuichi Murakami,
Yuko Higashi,
Naoya Matsunaga,
Satoru Koyanagi,
Shigehiro Ohdo
et al.
|
Full-length article
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pages 1636-1644.e3
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Down-regulated in Adenoma Cl/HCO3 Exchanger Couples With Na/H Exchanger 3 for NaCl Absorption in Murine Small Intestine
11 August 2008
Background & Aims: Electroneutral NaCl absorption across small intestine contributes importantly to systemic fluid balance. Disturbances in this process occur in both obstructive and diarrheal dis...
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Nancy M. Walker,
Janet E. Simpson,
Pei–Fen Yen,
Ravinder K. Gill,
Elizabeth V. Rigsby,
Jennifer M. Brazill,
Pradeep K. Dudeja,
Clifford W. Schweinfest,
Lane L. Clarke
et al.
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Full-length article
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pages 1645-1653.e3
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An Inactivating Mutation in HDAC2 Leads to Dysregulation of Apoptosis Mediated by APAF1
08 August 2008
Background & Aims: Histone deacetylases (HDACs) are important regulators of chromatin involved in silencing tumor suppressor genes. We examined mutation of HDAC2 and examined consequences of HDAC2...
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Christin L. Hanigan,
Manon van Engeland,
Adriaan P. De Bruine,
Kim A. Wouters,
Matty P. Weijenberg,
James R. Eshleman,
James G. Herman
et al.
|
Full-length article

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pages 1654-1664.e2
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Intestinal Differentiation in Zebrafish Requires Cdx1b, a Functional Equivalent of Mammalian Cdx2
01 August 2008
Background & Aims: The ParaHox transcription factor Cdx2 is an essential determinant of intestinal phenotype in mammals throughout development, influencing gut function, homeostasis, and epithelia...
|
Maria Vega C. Flores,
Chris J. Hall,
Alan J. Davidson,
Primal P. Singh,
Alhad A. Mahagaonkar,
Leonard I. Zon,
Kathryn E. Crosier,
Philip S. Crosier
et al.
|
Full-length article
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pages 1665-1675
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GATA4 Is Essential for Jejunal Function in Mice
04 August 2008
Background & Aims: Although the zinc-finger transcription factor GATA4 has been implicated in regulating jejunal gene expression, the contribution of GATA4 in controlling jejunal physiology has no...
|
Michele A. Battle,
Benjamin J. Bondow,
Moriah A. Iverson,
Scott J. Adams,
Ronald J. Jandacek,
Patrick Tso,
Stephen A. Duncan
et al.
|
Full-length article
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pages 1676-1686.e1
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| Basic-Liver, Pancreas, and Biliary Tract |
| |
Article Title |
Author(s) |
Type |
Pages |
|
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Mist1 Regulates Pancreatic Acinar Cell Proliferation Through p21CIP1/WAF1
04 August 2008
Background & Aims: Mist1 is a basic helix-loop-helix (bHLH) transcription factor that is important to the proper development of the exocrine pancreas. The aim of this study was to investigate the ...
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Di Jia,
Yan Sun,
Stephen F. Konieczny
|
Full-length article
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pages 1687-1697
|
|
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MEN1 Missense Mutations Impair Sensitization to Apoptosis Induced by Wild-Type Menin in Endocrine Pancreatic Tumor Cells
04 August 2008
Background & Aims: Missense mutations account for 30% of mutations identified in patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome. They raise several issues: the distinction b...
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Wissam Bazzi,
Maud Renon,
Cécile Vercherat,
Zeinab Hamze,
Annie Lacheretz–Bernigaud,
Hayian Wang,
Martine Blanc,
Colette Roche,
Alain Calender,
Jean–Alain Chayvialle,
Jean–Yves Scoazec,
Martine Cordier–Bussat
et al.
|
Full-length article
|
pages 1698-1709.e2
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|
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Antiviral Suppression vs Restoration of RIG-I Signaling by Hepatitis C Protease and Polymerase Inhibitors
24 July 2008
Background & Aims: Expression of the nonstructural protein (NS)3/4A protease in cells infected with hepatitis C virus (HCV) results in cleavage of the mitochondrial antiviral-signaling protein (MA...
|
Yuqiong Liang,
Hisashi Ishida,
Oliver Lenz,
Tse–I Lin,
Origène Nyanguile,
Kenny Simmen,
Richard B. Pyles,
Nigel Bourne,
MinKyung Yi,
Kui Li,
Stanley M. Lemon
et al.
|
Full-length article
|
pages 1710-1718.e2
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Neutralizing Host Responses in Hepatitis C Virus Infection Target Viral Entry at Postbinding Steps and Membrane Fusion
24 July 2008
Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic hepatitis worldwide. Viral attachment and entry, representing the first steps of virus-host cell interactions, are major ta...
|
Anita Haberstroh,
Eva K. Schnober,
Mirjam B. Zeisel,
Patric Carolla,
Heidi Barth,
Hubert E. Blum,
François–Loic Cosset,
George Koutsoudakis,
Ralf Bartenschlager,
Ann Union,
Erik Depla,
Ania Owsianka,
Arvind H. Patel,
Catherine Schuster,
Françoise Stoll–Keller,
Michel Doffoël,
Marlène Dreux,
Thomas F. Baumert
et al.
|
Full-length article
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pages 1719-1728.e1
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Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis
04 August 2008
Background & Aims: Although angiogenesis is closely associated with liver fibrosis, the angiogenic factors involved in liver fibrosis are not well characterized. Angiopoietin 1 is an angiogenic cy...
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Kojiro Taura,
Samuele De Minicis,
Ekihiro Seki,
Etsuro Hatano,
Keiko Iwaisako,
Christoph H. Osterreicher,
Yuzo Kodama,
Kouichi Miura,
Iwao Ikai,
Shinji Uemoto,
David A. Brenner
et al.
|
Full-length article
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pages 1729-1738
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Extracellular Adenosine Production by Ecto-5′-Nucleotidase Protects During Murine Hepatic Ischemic Preconditioning
04 August 2008
Background & Aims: The liver tolerates ischemia/reperfusion (IR) poorly. The discovery of ischemic preconditioning (IP) has raised hopes that natural pathways could be activated to increase hepati...
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Melanie L. Hart,
Chressen Much,
Iris C. Gorzolla,
Jens Schittenhelm,
Doris Kloor,
Gregory L. Stahl,
Holger K. Eltzschig
et al.
|
Full-length article

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pages 1739-1750.e3
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Regulated Catalysis of Extracellular Nucleotides by Vascular CD39/ENTPD1 Is Required for Liver Regeneration
01 August 2008
Background & Aims: Little is known about how endothelial cells respond to injury, regulate hepatocyte turnover and reconstitute the hepatic vasculature. We aimed to determine the effects of the va...
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Guido Beldi,
Yan Wu,
Xiaofeng Sun,
Masato Imai,
Keiichi Enjyoji,
Eva Csizmadia,
Daniel Candinas,
Laurie Erb,
Simon C. Robson
et al.
|
Full-length article
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pages 1751-1760
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| Continuing Medical Education (CME) Activities |
| |
Article Title |
Author(s) |
Type |
Pages |
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Continuing Medical Education Exam 1: November 2008
09 October 2008
|
Michael B. Wallace
|
Examination
|
pages 1761-1762
|
|
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Continuing Medical Education Exam 2: November 2008
10 October 2008
|
|
Examination
|
page 1763
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| AGA Institute |
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Article Title |
Author(s) |
Type |
Pages |
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AGA Institute Future Trends Committee Report: The Future of Gastroenterology Training Programs in the United States
The American Gastroenterological Association (AGA) Institute Future Trends Committee (FTC) developed this report based on a consensus conference it convened on March 8–9, 2008, in Washington, DC. The ...
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Timothy C. Wang,
Fabio Cominelli,
David E. Fleischer,
James M. Gordon,
Robert M. Glickman,
David Limsui,
Kenneth R. McQuaid,
Marshall Montrose,
Pankaj J. Pasricha,
Don W. Powell,
William A. Rowe,
William J. Sandborn,
Andrea Todisco
et al.
|
Full-length article
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pages 1764-1789.e2
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| Selected Summaries |
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Article Title |
Author(s) |
Type |
Pages |
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Should All Patients With Acute Gastrointestinal Hemorrhage Receive Intravenous Proton Pump Inhibitor Therapy Before Endoscopy?
10 October 2008
Al-Sabah S, Barkun A, Herba K, et al. (Division of General Surgery, McGill University, Montreal, Quebec, Canada). Cost-effectiveness of proton pump inhibition before endoscopy in upper gastrointestina...
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Lauren B. Gerson
|
Discussion
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pages 1790-1792
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Reply
09 October 2008
We agree with Dr Gerson's insightful review. Some additional points can be made to put into perspective the findings of our cost-effectiveness analysis. In the commentary's review of the existing lite...
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Alan N. Barkun
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Discussion
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page 1792
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Methylnaltrexone: A New Treatment for an Old Problem
09 October 2008
Thomas J, Karver S, Cooney GA, et al. (San Diego Hospice and Palliative Medicine, San Diego, California). Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med 2008;358:23...
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Amol S. Rangnekar,
William D. Chey
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Discussion
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pages 1792-1794
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Should Surgery Replace Pneumatic Dilation in Achalasia?
06 October 2008
Ferulano GP, Dilillo S, D'Ambra M, et al. (Systemic Pathology, University of Naples Federico II, Naples, Italy). Short and long term results of the laparoscopic Heller–Dor myotomy. The influence of ag...
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Michael F. Vaezi
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Discussion
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pages 1794-1796
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Reply
10 October 2008
As surgeons dedicated to the repair of upper and lower gastrointestinal tract dysfunction, the main goal of our paper was to evaluate the influence of 2 different conditions on the surgical treatment ...
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Giuseppe P. Ferulano,
Saverio Dilillo,
Michele D'Ambra,
Ruggero Lionetti,
Rossella Brunaccino,
Domenico Fico,
Domenico Pelaggi
et al.
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Discussion
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page 1796
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Ulcerative Colitis and Crohn's Disease Genetics: More Similar Than We Thought?
06 October 2008
Fisher SA, Tremelling M, Anderson CA, et al. (Department of Medical and Molecular Genetics, King's College London School of Medicine, London, UK; others). Genetic determinants of ulcerative colitis in...
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Miquel Sans,
Antoni Castells
|
Discussion
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pages 1796-1798
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| Print and Media Reviews |
| |
Article Title |
Author(s) |
Type |
Pages |
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Book review
09 October 2008
Endoscopic mucosal resection (EMR) is an emerging endotherapy technique that can supplant the need for operative resection in the treatment of many superficial gastrointestinal cancers. In this practi...
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Gregory G. Ginsberg
|
Book review
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page 1799
|
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Book review
09 October 2008
This conveniently sized American textbook is dedicated to the evolving topic of cholestasis. The editors are known to the audience and are joined by a wider cohort of contributing physicians with vari...
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Gideon M. Hirschfield,
E. Jenny Heathcote
|
Book review
|
pages 1799-1800
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