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This Month in Gastroenterology
This Month in Gastroenterology, 21 December 2009 Jan Tack, John M. Carethers pages 405-407 Preview | Full Text | Full-Text PDF (540 KB)
Gastroenterology and Hepatology News
More Than $500 Million Spent for Lobbying by Health Care Interest Groups in 2009, 17 December 2009 Les Lang page 408 Preview | Full Text | Full-Text PDF (148 KB)
GINA, Imperfect But Official, 17 December 2009 Les Lang page 408 Preview | Full Text | Full-Text PDF (147 KB)
Sustained Virologic Response to Hepatitis C Virus Therapy and Spontaneous Viral Clearance Found Linked to Genotype, 17 December 2009 Les Lang page 409 Preview | Full Text | Full-Text PDF (126 KB)
New Appointments to the Board of Editors, 17 December 2009 Les Lang pages 409-410 Preview | Full Text | Full-Text PDF (429 KB)
Mini-Review and Perspective
State of Research in Pediatric Gastroenterology, Hepatology, and Nutrition: 2010 and Beyond, 17 December 2009 W. Allan Walker, Philip Sherman, Benjamin L. Shneider, Mitchell Cohen, John Barnard pages 411-416.e2 Preview | Full Text | Full-Text PDF (361 KB)
Comment From the Editors
The Development of Clinical Guidelines by the American Gastroenterological Association, 23 December 2009 Themistocles Dassopoulos, John M. Inadomi, James D. Lewis, John I. Allen pages 417-418 Preview | Full Text | Full-Text PDF (205 KB)
Editorials
Optical Molecular Imaging Approaches in Colorectal Cancer, 21 December 2009 Umar Mahmood pages 419-422 Preview | Full Text | Full-Text PDF (278 KB)
IV or Not IV? Just One of the Antibiotic Questions in Whipple's Disease, 23 December 2009 Cynthia L. Sears, Sara E. Cosgrove pages 422-426 Preview | Full Text | Full-Text PDF (806 KB)
Sonic Hedgehog: A Link Between Inflammation, Gastric Atrophy, and Acid Suppression?, 23 December 2009 Willemijn A. Van Dop, Gijs R. Van Den Brink pages 426-429 Preview | Full Text | Full-Text PDF (428 KB)
The Role of Bile Acids in Gallstone-Induced Pancreatitis, 23 December 2009 Markus M. Lerch, Ali A. Aghdassi pages 429-433 Preview | Full Text | Full-Text PDF (1325 KB)
Clinical Challenges and Images in GI
Colonoscopy: An Unusual Complication, 23 December 2009 Adam C. Alder, Daniel L. Scott, Jeffrey D. Browning page 434 Preview | Full Text | Full-Text PDF (632 KB)
Electronic Clinical Challenges and Images in GI
Recurrent Nausea, Vomiting, and Abdominal Pain, 21 December 2009 Christine Y. Hachem, N. Cem Balci, Devang Desai pages e1-e2 Preview | Full Text | Full-Text PDF (538 KB)
Esophageal Blebs and Blisters, 21 December 2009 Klaus Mönkemüller, Helmut Neumann, Lucía C. Fry pages e3-e4 Preview | Full Text | Full-Text PDF (477 KB)
A Georgian Woman With Dysphagia and Stridor, 25 December 2009 Philipp Kiewe, Stefanie Hammersen, Thomas Schneider pages e5-e6 Preview | Full Text | Full-Text PDF (735 KB)
An Unusual Liver Mass, 28 December 2009 Paolo Cabassa, Mario Morone, Luigi Matricardi pages e7-e9 Preview | Full Text | Full-Text PDF (1049 KB)
Imaging and Advanced Technology
In Vivo Molecular Imaging of Colorectal Cancer With Confocal Endomicroscopy by Targeting Epidermal Growth Factor Receptor, 22 October 2009 Martin Goetz, Alex Ziebart, Sebastian Foersch, Michael Vieth, Maximilian J. Waldner, Peter Delaney, Peter R. Galle, Markus F. Neurath, Ralf Kiesslich pages 435-446 Abstract | Full Text | Full-Text PDF (3944 KB)
Reviews in Basic and Clinical Gastroenterology
Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection, 14 December 2009 Christoph Sarrazin, Stefan Zeuzem pages 447-462 Abstract | Full Text | Full-Text PDF (1339 KB)
Clinical-Alimentary Tract
Mucosal Healing Predicts Sustained Clinical Remission in Patients With Early-Stage Crohn's Disease, 09 October 2009 Filip Baert, Liesbeth Moortgat, Gert Van Assche, Philip Caenepeel, Philippe Vergauwe, Martine De Vos, Pieter Stokkers, Daniel Hommes, Paul Rutgeerts, Severine Vermeire, Geert D'Haens, Belgian Inflammatory Bowel Disease Research Group, North-Holland Gut Club pages 463-468 Abstract | Full Text | Full-Text PDF (433 KB)
Postprandial Changes in Small Bowel Water Content in Healthy Subjects and Patients With Irritable Bowel Syndrome, 11 November 2009 Luca Marciani, Eleanor F. Cox, Caroline L. Hoad, Susan Pritchard, John J. Totman, Steve Foley, Amisha Mistry, Steven Evans, Penny A. Gowland, Robin C. Spiller pages 469-477.e1 Abstract | Full Text | Full-Text PDF (1405 KB)
Efficacy of Ceftriaxone or Meropenem as Initial Therapies in Whipple's Disease, 30 October 2009 Gerhard E. Feurle, Natascha S. Junga, Thomas Marth pages 478-486 Abstract | Full Text | Full-Text PDF (920 KB)
Risk and Epidemiological Time Trends of Gastric Cancer in Lynch Syndrome Carriers in The Netherlands, 09 November 2009 Lisette G. Capelle, Nicole C.T. Van Grieken, Hester F. Lingsma, Ewout W. Steyerberg, Willem J. Klokman, Marco J. Bruno, Hans F.A. Vasen, Ernst J. Kuipers pages 487-492 Abstract | Full Text | Full-Text PDF (382 KB)
Clinical Advances in Liver, Pancreas, and Biliary Tract
Des-γ-Carboxy Prothrombin and α-Fetoprotein as Biomarkers for the Early Detection of Hepatocellular Carcinoma, 22 October 2009 Anna S. Lok, Richard K. Sterling, James E. Everhart, Elizabeth C. Wright, John C. Hoefs, Adrian M. Di Bisceglie, Timothy R. Morgan, Hae–Young Kim, William M. Lee, Herbert L. Bonkovsky, Jules L. Dienstag, HALT-C Trial Group pages 493-502 Abstract | Full Text | Full-Text PDF (786 KB)
Peginterferon Alfa-2a/Ribavirin for 48 or 72 Weeks in Hepatitis C Genotypes 1 and 4 Patients With Slow Virologic Response, 11 November 2009 Peter Ferenci, Hermann Laferl, Thomas–Matthias Scherzer, Andreas Maieron, Harald Hofer, Rudolf Stauber, Michael Gschwantler, Harald Brunner, Christoph Wenisch, Martin Bischof, Michael Strasser, Christian Datz, Wolfgang Vogel, Karin Löschenberger, Petra Steindl–Munda, Austrian Hepatitis Study Group pages 503-512.e1 Abstract | Full Text | Full-Text PDF (1020 KB)
Clinical-Liver, Pancreas, and Biliary Tract
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression, 26 October 2009 Gary L. Davis, Miriam J. Alter, Hashem El–Serag, Thierry Poynard, Linda W. Jennings pages 513-521.e6 Abstract | Full Text | Full-Text PDF (1331 KB)
Screening and Early Treatment of Migrants for Chronic Hepatitis B Virus Infection Is Cost-Effective, 30 October 2009 Irene K. Veldhuijzen, Mehlika Toy, Susan J.M. Hahné, G. Ardine De Wit, Solko W. Schalm, Robert A. de Man, Jan Hendrik Richardus pages 522-530 Abstract | Full Text | Full-Text PDF (559 KB)
Asymptomatic Pancreatic Cystic Neoplasms: Maximizing Survival and Quality of Life Using Markov-Based Clinical Nomograms, 09 October 2009 Benjamin M. Weinberg, Brennan M.R. Spiegel, James S. Tomlinson, James J. Farrell pages 531-540 Abstract | Full Text | Full-Text PDF (591 KB)
History of Peptic Ulcer Disease and Pancreatic Cancer Risk in Men, 09 October 2009 Ying Bao, Donna Spiegelman, Ruifeng Li, Edward Giovannucci, Charles S. Fuchs, Dominique S. Michaud pages 541-549 Abstract | Full Text | Full-Text PDF (304 KB)
Basic-Alimentary Tract
Loss of Parietal Cell Expression of Sonic Hedgehog Induces Hypergastrinemia and Hyperproliferation of Surface Mucous Cells, 11 November 2009 Chang Xiao, Sally A. Ogle, Michael A. Schumacher, Melissa A. Orr–Asman, Marian L. Miller, Nantaporn Lertkowit, Andrea Varro, Frederic Hollande, Yana Zavros pages 550-561.e8 Abstract | Full Text | Full-Text PDF (5127 KB)
Interleukin-1β Promotes Gastric Atrophy Through Suppression of Sonic Hedgehog, 02 November 2009 Meghna Waghray, Yana Zavros, Milena Saqui–Salces, Mohamad El–Zaatari, C. Bharath Alamelumangapuram, Andrea Todisco, Kathryn A. Eaton, Juanita L. Merchant pages 562-572.e2 Abstract | Full Text | Full-Text PDF (4046 KB)
Protease-Activated Receptor-1 Down-regulates the Murine Inflammatory and Humoral Response to Helicobacter pylori, 25 August 2009 Janet L.K. Wee, Yok–Teng Chionh, Garrett Z. Ng, Stacey N. Harbour, Cody Allison, Charles N. Pagel, Eleanor J. Mackie, Hazel M. Mitchell, Richard L. Ferrero, Philip Sutton pages 573-582 Abstract | Full Text | Full-Text PDF (1952 KB)
Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in Mice, 30 October 2009 Edwin F. de Zoeten, Liqing Wang, Hong Sai, Wolfgang H. Dillmann, Wayne W. Hancock pages 583-594 Abstract | Full Text | Full-Text PDF (3606 KB) | Bonus Content
Mesalamine Inhibits Epithelial β-Catenin Activation in Chronic Ulcerative Colitis, 30 October 2009 Jeffrey B. Brown, Goo Lee, Elizabeth Managlia, Gery R. Grimm, Ramanarao Dirisina, Tatiana Goretsky, Paul Cheresh, Nichole R. Blatner, Khashayarsha Khazaie, Guang–Yu Yang, Linheng Li, Terrence A. Barrett pages 595-605.e3 Abstract | Full Text | Full-Text PDF (5089 KB)
Prolyl Hydroxylase-3 Is Down-regulated in Colorectal Cancer Cells and Inhibits IKKβ Independent of Hydroxylase Activity, 27 September 2009 Jing Xue, Xuebing Li, Shi Jiao, Ye Wei, Guohao Wu, Jing Fang pages 606-615 Abstract | Full Text | Full-Text PDF (1802 KB) | Bonus Content
Reg IV Regulates Normal Intestinal and Colorectal Cancer Cell Susceptibility to Radiation-Induced Apoptosis, 09 November 2009 Kumar S. Bishnupuri, Qizhi Luo, Satheesh K. Sainathan, Kento Kikuchi, Sripathi M. Sureban, Mekala Sabarinathan, Jennifer H. Gross, Konrad Aden, Randal May, Courtney W. Houchen, Shrikant Anant, Brian K. Dieckgraefe pages 616-626.e2 Abstract | Full Text | Full-Text PDF (2368 KB)
CDX Transcription Factors Positively Regulate Expression of Solute Carrier Family 5, Member 8 in the Colonic Epithelium, 09 November 2009 Fumihiko Kakizaki, Koji Aoki, Hiroyuki Miyoshi, Nancy Carrasco, Masahiro Aoki, Makoto M. Taketo pages 627-635 Abstract | Full Text | Full-Text PDF (1770 KB) | Bonus Content
The Intestinal Nuclear Receptor Signature With Epithelial Localization Patterns and Expression Modulation in Tumors, 09 October 2009 Salvatore Modica, Francoise Gofflot, Stefania Murzilli, Andria D'Orazio, Lorena Salvatore, Fabio Pellegrini, Antonio Nicolucci, Giovanni Tognoni, Massimiliano Copetti, Rosa Valanzano, Serena Veschi, Renato Mariani–Costantini, Giuseppe Palasciano, Kristina Schoonjans, Johan Auwerx, Antonio Moschetta pages 636-648.e12 Abstract | Full Text | Full-Text PDF (7658 KB)
Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+/H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2, 05 October 2009 Songbai Lin, Sunil Yeruva, Peijian He, Anurag Kumar Singh, Huanchun Zhang, Mingmin Chen, Georg Lamprecht, Hugo R. de Jonge, Ming Tse, Mark Donowitz, Boris M. Hogema, Jerold Chun, Ursula Seidler, C. Chris Yun pages 649-658 Abstract | Full Text | Full-Text PDF (1420 KB) | Bonus Content
Release of 5-Hydroxytryptamine From the Mucosa Is Not Required for the Generation or Propagation of Colonic Migrating Motor Complexes, 25 September 2009 Damien J. Keating, Nick J. Spencer pages 659-670.e2 Abstract | Full Text | Full-Text PDF (3312 KB)
Basic-Liver, Pancreas, and Biliary Tract
Silymarin Inhibits In Vitro T-Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection, 25 September 2009 Chihiro Morishima, Margaret C. Shuhart, Chia C. Wang, Denise M. Paschal, Minjun C. Apodaca, Yanze Liu, Derek D. Sloan, Tyler N. Graf, Nicholas H. Oberlies, David Y.–W. Lee, Keith R. Jerome, Stephen J. Polyak pages 671-681.e2 Abstract | Full Text | Full-Text PDF (2668 KB)
Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B, 05 October 2009 Paola Fisicaro, Caterina Valdatta, Marco Massari, Elisabetta Loggi, Elisabetta Biasini, Luca Sacchelli, Maria Cristina Cavallo, Enrico M. Silini, Pietro Andreone, Gabriele Missale, Carlo Ferrari pages 682-693.e4 Abstract | Full Text | Full-Text PDF (5023 KB)
Heme Oxygenase-1 Protects Against Steatohepatitis in Both Cultured Hepatocytes and Mice, 09 October 2009 Jun Yu, Eagle S.H. Chu, Ruizhi Wang, Shiyan Wang, Chung W. Wu, Vincent W.S. Wong, Henry L.Y. Chan, Geofferey C. Farrell, Joseph J.Y. Sung pages 694-704.e1 Abstract | Full Text | Full-Text PDF (2630 KB)
MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis, 19 October 2009 Jelena Mann, David C.K. Chu, Aidan Maxwell, Fiona Oakley, Nian–Ling Zhu, Hidekazu Tsukamoto, Derek A. Mann pages 705-714.e4 Abstract | Full Text | Full-Text PDF (2196 KB)
Biliary Acute Pancreatitis in Mice is Mediated by the G-Protein−Coupled Cell Surface Bile Acid Receptor Gpbar1, 09 November 2009 George Perides, Johanna M. Laukkarinen, Galya Vassileva, Michael L. Steer pages 715-725 Abstract | Full Text | Full-Text PDF (1765 KB) | Bonus Content
Cathepsin L Inactivates Human Trypsinogen, Whereas Cathepsin L-Deletion Reduces the Severity of Pancreatitis in Mice, 09 November 2009 Thomas Wartmann, Julia Mayerle, Thilo Kähne, Miklós Sahin–Tóth, Manuel Ruthenbürger, Rainer Matthias, Anne Kruse, Thomas Reinheckel, Christoph Peters, F. Ulrich Weiss, Matthias Sendler, Hans Lippert, Hans–Ulrich Schulz, Ali Aghdassi, Annegret Dummer, Steffen Teller, Walter Halangk, Markus M. Lerch pages 726-737 Abstract | Full Text | Full-Text PDF (3022 KB) | Bonus Content
Continuing Medical Education (CME) Activities
February CME Exam 1 Questions, 21 December 2009 pages e10-e11 Preview | Full-Text PDF (97 KB)
February CME Exam 2 Questions, 21 December 2009 pages e11-e12 Preview | Full-Text PDF (94 KB)
IBD Guide 2009 CME Exam 3, 23 December 2009 pages e12-e13 Preview | Full-Text PDF (95 KB)
AGA
AGA Medical Position Statement on the Diagnosis and Management of Colorectal Neoplasia in Inflammatory Bowel Disease Francis A. Farraye, Robert D. Odze, Jayne Eaden, Steven H. Itzkowitz, AGA Institute Medical Position Panel on Diagnosis and Management of Colorectal Neoplasia in Inflammatory Bowel Disease pages 738-745 Abstract | Full Text | Full-Text PDF (249 KB)
AGA Technical Review on the Diagnosis and Management of Colorectal Neoplasia in Inflammatory Bowel Disease Francis A. Farraye, Robert D. Odze, Jayne Eaden, Steven H. Itzkowitz pages 746-774.e4 Preview | Full Text | Full-Text PDF (2031 KB)
Selected Summaries
Antidepressants for Irritable Bowel Syndrome: Reappraisal for the Nondepressed, 21 December 2009 Lauren B. Gerson pages 775-777 Preview | Full Text | Full-Text PDF (158 KB)
Reply, 21 December 2009 Alexander C. Ford page 777 Preview | Full Text | Full-Text PDF (125 KB)
Failure of Interferon to Prevent Disease Progression and Liver Cancer in Hepatitis C Virus Infection: Proof of Absence or Absence of Proof?, 21 December 2009 Carlos Rodríguez de Lope, Jordi Bruix pages 777-779 Preview | Full Text | Full-Text PDF (154 KB)
Gut Microbiota Control Gut Permeability Through GLP-2, 21 December 2009 Alastair J.M. Watson, Carrie A. Duckworth pages 779-781 Preview | Full Text | Full-Text PDF (154 KB)
Reply, 21 December 2009 Patrice D. Cani, Nathalie M. Delzenne page 781 Preview | Full Text | Full-Text PDF (123 KB)
Are Immunoglobulin G4-Positive Multiorgan Lymphoproliferative Syndrome and Autoimmune Pancreatitis Different Manifestations of a Common Clinicopathologic Entity?, 21 December 2009 Tsutomu Chiba pages 781-784 Preview | Full Text | Full-Text PDF (161 KB)
Reply, 21 December 2009 Yasufumi Masaki, Hisanori Umehara page 784 Preview | Full Text | Full-Text PDF (107 KB)
Print and Media Reviews
Probiotics in Pediatric Medicine, 21 December 2009 Jeffry A. Katz page 785 Preview | Full Text | Full-Text PDF (122 KB)
Understanding the Irritable Gut, 21 December 2009 Monthira Maneeratanaporn, William D. Chey page 786 Preview | Full Text | Full-Text PDF (118 KB)
Gastrointestinal Cancer Atlas for Endoscopic Therapy, 21 December 2009 Ravi N. Sharaf, Jacques Van Dam pages 786-787 Preview | Full Text | Full-Text PDF (129 KB)
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