Gastroenterology
Volume 142, Issue 4 , Pages 938-946 , April 2012

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

  • Virginia Hernández–Gea

      Affiliations

    • Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York
  • ,
  • Zahra Ghiassi–Nejad

      Affiliations

    • Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York
  • ,
  • Raphael Rozenfeld

      Affiliations

    • Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, New York
  • ,
  • Ronald Gordon

      Affiliations

    • Department of Pathology, Mount Sinai School of Medicine, New York, New York
  • ,
  • Maria Isabel Fiel

      Affiliations

    • Department of Pathology, Mount Sinai School of Medicine, New York, New York
  • ,
  • Zhenyu Yue

      Affiliations

    • Department of Neurology and Neuroscience, Mount Sinai School of Medicine, New York, New York
  • ,
  • Mark J. Czaja

      Affiliations

    • Department of Medicine and Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York
  • ,
  • Scott L. Friedman

      Affiliations

    • Division of Liver Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York
    • Corresponding Author InformationReprint requests Address requests for reprints to: Scott L. Friedman, MD, Box 1123, Mount Sinai School of Medicine, 1425 Madison Avenue, Room 11-70C, New York, New York 10029-6574. fax: (212) 849-2574

Received 19 September 2011 ,Accepted 31 December 2011.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by US National Institutes of Health grants (RO1DK56621, R01 AA020709, KO5AA018408, P20AA017067, 5T32GM007280, R01DK044234, R01DK061498, and R01NS060123).

PII: S0016-5085(12)00012-1

doi: 10.1053/j.gastro.2011.12.044

Gastroenterology
Volume 142, Issue 4 , Pages 938-946 , April 2012