Estimates of Early Death, Acute Liver Failure, and Long-term Mortality Among Live Liver Donors

Trends in LDLT in the United States, 1994–2010. (A) The number of LDLTs performed in the United States (1994–2010) by procedure type: left lateral segment LDLT (green), left lobe adult-to-child LDLT (lime), left lobe adult-to-adult LDLT (yellow), and right lobe adult-to-adult LDLT (orange). (B) The number of centers performing LDLT: those performing only adult-to-child LDLT (green) and those performing adult-to-adult (and/or adult-to-child) LDLT (orange). Only 3 adult-to-adult LDLTs were reported to the OPTN between 1994 and 1996, and these included one left lateral segment and 2 left lobe donations. The first published report of a right lobe adult-to-adult LDLT in the United States was of one performed in 1997,⁹ and the subsequent exponential growth in adult-to-adult LDLT is generally attributed to the expansion of this novel procedure.¹⁴

Kaplan–Meier curves comparing the cumulative mortality of live liver donors, matched live kidney donors, and a matched NHANES III cohort (identified among participants in NHANES III).