Gastroenterology
Volume 139, Issue 5 , Pages 1740-1752, November 2010

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

  • Wen–Xing Ding

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas
    • ,
  • Min Li

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Xiaoyun Chen

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Hong–Min Ni

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas
    • ,
  • Chih–Wen Lin

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Wentao Gao

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Binfeng Lu

      Affiliations

    • Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Donna B. Stolz

      Affiliations

    • Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • ,
  • Dahn L. Clemens

      Affiliations

    • Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska
    • Department of Internal Medicine, Veterans Administration Medical Center, Omaha, Nebraska
    • ,
  • Xiao–Ming Yin

      Affiliations

    • Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    • Corresponding Author InformationReprint requests Address requests for reprints to: Xiao-Ming Yin, MD, PhD, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202. fax: (317) 274-1782

Received 3 September 2009; accepted 9 July 2010. published online 26 July 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported in part by NIH (R01 CA83817, R01 CA111456 to X.-M.Y.; R01 AA11291 to D.L.C.; R21 AA017421 to W.-X.D.) and the Department of Veterans Affairs (to D.L.C.).

PII: S0016-5085(10)01104-2

doi:10.1053/j.gastro.2010.07.041

Gastroenterology
Volume 139, Issue 5 , Pages 1740-1752, November 2010

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