Gastroenterology
Volume 139, Issue 3 , Pages 735-741.e1 , September 2010

Biomarker and Drug Discovery for Gastroenterology Through Translational Bioinformatics

  • Joel T. Dudley

      Affiliations

    • Program in Biomedical Informatics, Stanford University School of Medicine, Stanford, California
    • Department of Pediatrics, Stanford University School of Medicine, Stanford, California
    • Lucile Packard Children's Hospital, Palo Alto, California
    • ,
  • Atul J. Butte

      Affiliations

    • Department of Pediatrics, Stanford University School of Medicine, Stanford, California
    • Lucile Packard Children's Hospital, Palo Alto, California
    • Corresponding Author InformationReprint requests Address requests for reprints to: Atul J. Butte, Department of Pediatrics, Stanford University School of Medicine, 251 Campus Drive X-163, MS-5415, Stanford, CA, 94305-5415

References 

  1. Butte AJ. Translational bioinformatics: coming of age. J Am Med Inform Assoc. 2008;15:709–714
  2. Butte AJ, Chen R. Finding disease-related genomic experiments within an international repository: first steps in translational bioinformatics. AMIA Annu Symp Proc. 2006;106–110
  3. Dudley JT, Tibshirani R, Deshpande T, et al. Disease signatures are robust across tissues and experiments. Mol Syst Biol. 2009;5:307
  4. English SB, Butte AJ. Evaluation and integration of 49 genome-wide experiments and the prediction of previously unknown obesity-related genes. Bioinformatics (Oxford, England). 2007;23:2910
  5. Sirota M, Schaub MA, Batzoglou S, et al. Autoimmune disease classification by inverse association with SNP alleles. PLoS Genet. 2009;5:e1000792

 Conflicts of interest The authors disclose the following: AJB is or has served as a scientific advisor and/or consultant to NuMedii, Genstruct, Prevendia, Tercica, Eli Lilly and Company, and Johnson and Johnson. JTD has served as a consultant to NuMedii.

 Funding Grant support from the National Library of Medicine (T15 LM007033 and R01 LM009719).

PII: S0016-5085(10)01076-0

doi: 10.1053/j.gastro.2010.07.024

Gastroenterology
Volume 139, Issue 3 , Pages 735-741.e1 , September 2010

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