Gastroenterology
Volume 139, Issue 3 , Pages 716-718 , September 2010

Chronic Cough and Gastroesophageal Reflux Disease: New Twists to the Riddle

  • Peter J. Kahrilas

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Peter J. Kahrilas, MD, Northwestern University, Feinberg School of Medicine, Division of Gastroenterology, Department of Medicine, 676 North St. Clair Street, Suite 1400, Chicago, Illinois 60611. fax: (312) 695-3999

References 

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  2. Chung KF, Pavord ID. Chronic cough 1 (Prevalence, pathogenesis, and causes of chronic cough). Lancet. 2008;371:1364–1374
  3. Morice AH, Fontana GA, Sovijarvi AR, et al. The diagnosis and management of chronic cough. Eur Respir J. 2004;24:481–492
  4. Sifrim D, Castell D, Dent J, Kahrilas PJ. Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. Gut. 2004;53:1024–1031
  5. Tutuian R, Mainie I, Agrawal A, et al. Nonacid reflux in patients with chronic cough on acid-suppressive therapy. Chest. 2006;130:386–391
  6. Sifrim D, Dupont L, Blondeau K, et al. Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring. Gut. 2005;54:449–454
  7. Bogte A, Bredenoord AJ, Smout AJ. Diagnostic yield of oesophageal pH monitoring in patients with chronic unexplained cough. Scand J Gastroenterol. 2008;43:13–19
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  10. Kahrilas PJ, Shaheen NJ, Vaezi M AGAI Medical Position Panel on GERD management. AGAI medical position statement: management of gastroesophageal reflux disease. Gastroenterology. 2008;135:1383–1391
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  13. Javorkova N, Varechova S, Pecova R, et al. Acidification of the oesophagus acutely increases the cough sensitivity in patients with gastro-oesophageal reflux and chronic cough. Neurogastroenterol Motil. 2008;20:119–124
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  15. Vakil N, van Zanten SV, Kahrilas P, et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900–1920
  16. Chang AB, Lasserson TJ, Kiljander TO, et al. Systematic review and meta-analysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux. BMJ. 2006;332:11–17
  17. Allen CJ, Anvari M. Does laparoscopic fundoplication provide long-term control of gastro-esophageal reflux related cough?. Surg Endosc. 2004;18:633–637

 Conflicts of interest The author discloses the following: Dr Kahrilas is a paid consultant for AstraZeneca, Eisai, EndoGastric Solutions, Novartis, Movetis, Reckitt Benckiser, Torax, and Xenoport.

 Funding This work was supported by grant R01 DK00646 (P.J.K.) from the Public Health Service.

PII: S0016-5085(10)01066-8

doi: 10.1053/j.gastro.2010.07.014

Gastroenterology
Volume 139, Issue 3 , Pages 716-718 , September 2010

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