Gastroenterology
Volume 139, Issue 3 , Pages 869-881.e9 , September 2010

Phosphoinositide 3-Kinase Signaling Mediates β-Catenin Activation in Intestinal Epithelial Stem and Progenitor Cells in Colitis

  • Goo Lee

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Tatiana Goretsky

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Elizabeth Managlia

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Ramanarao Dirisina

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Ajay Pal Singh

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Jeffrey B. Brown

      Affiliations

    • Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Randal May

      Affiliations

    • Department of Medicine, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma
    • ,
  • Guang–Yu Yang

      Affiliations

    • Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Josette William Ragheb

      Affiliations

    • Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • B. Mark Evers

      Affiliations

    • Department of Surgery and Lucille P. Markey Cancer Center, University of Kentucky, Lexington, Kentucky
    • ,
  • Christopher R. Weber

      Affiliations

    • Department of Pathology, University of Chicago Pritzker School of Medicine, Chicago, Illinois
    • ,
  • Jerrold R. Turner

      Affiliations

    • Department of Pathology, University of Chicago Pritzker School of Medicine, Chicago, Illinois
    • ,
  • Xi C. He

      Affiliations

    • Stowers Institute for Medical Research, Kansas City, Missouri
    • ,
  • Rebecca B. Katzman

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Linheng Li

      Affiliations

    • Stowers Institute for Medical Research, Kansas City, Missouri
    • Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas
    • ,
  • Terrence A. Barrett

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • Corresponding Author InformationReprint requests Address requests for reprints to: Terrence A. Barrett, MD, Division of Gastroenterology, Northwestern University, 676 North St. Claire, Suite 1400, Chicago, Illinois 60611. fax: (312) 695-3999

Received 13 November 2009 ,Accepted 19 May 2010.

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 View this article's video abstract at www.gastrojournal.org

 Conflicts of interest The authors disclose no conflicts.

 Funding Support was provided by National Institutes of Health grants DK54778 and DKAI061701 (T.A.B.), and grant DK066161 (J.R.T.).

PII: S0016-5085(10)00767-5

doi: 10.1053/j.gastro.2010.05.037

Gastroenterology
Volume 139, Issue 3 , Pages 869-881.e9 , September 2010

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