Gastroenterology
Volume 139, Issue 3 , Pages 869-881.e9 , September 2010

Phosphoinositide 3-Kinase Signaling Mediates β-Catenin Activation in Intestinal Epithelial Stem and Progenitor Cells in Colitis

  • Goo Lee

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Tatiana Goretsky

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Elizabeth Managlia

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Ramanarao Dirisina

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Ajay Pal Singh

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Jeffrey B. Brown

      Affiliations

    • Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Randal May

      Affiliations

    • Department of Medicine, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma
    • ,
  • Guang–Yu Yang

      Affiliations

    • Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Josette William Ragheb

      Affiliations

    • Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • B. Mark Evers

      Affiliations

    • Department of Surgery and Lucille P. Markey Cancer Center, University of Kentucky, Lexington, Kentucky
    • ,
  • Christopher R. Weber

      Affiliations

    • Department of Pathology, University of Chicago Pritzker School of Medicine, Chicago, Illinois
    • ,
  • Jerrold R. Turner

      Affiliations

    • Department of Pathology, University of Chicago Pritzker School of Medicine, Chicago, Illinois
    • ,
  • Xi C. He

      Affiliations

    • Stowers Institute for Medical Research, Kansas City, Missouri
    • ,
  • Rebecca B. Katzman

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • ,
  • Linheng Li

      Affiliations

    • Stowers Institute for Medical Research, Kansas City, Missouri
    • Department of Pathology and Laboratory Medicine, Kansas University Medical Center, Kansas City, Kansas
    • ,
  • Terrence A. Barrett

      Affiliations

    • Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
    • Corresponding Author InformationReprint requests Address requests for reprints to: Terrence A. Barrett, MD, Division of Gastroenterology, Northwestern University, 676 North St. Claire, Suite 1400, Chicago, Illinois 60611. fax: (312) 695-3999

Received 13 November 2009 ,Accepted 19 May 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Support was provided by National Institutes of Health grants DK54778 and DKAI061701 (T.A.B.), and grant DK066161 (J.R.T.).

PII: S0016-5085(10)00767-5

doi: 10.1053/j.gastro.2010.05.037

Gastroenterology
Volume 139, Issue 3 , Pages 869-881.e9 , September 2010

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