Gastroenterology
Volume 139, Issue 2 , Pages 474-482 , August 2010

Incidence and Determinants of Spontaneous Hepatitis B Surface Antigen Seroclearance: A Community-Based Follow-Up Study

  • Jessica Liu

      Affiliations

    • Rollins School of Public Health, Emory University, Atlanta, Georgia
    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
  • ,
  • Hwai–I. Yang

      Affiliations

    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
  • ,
  • Mei–Hsuan Lee

      Affiliations

    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
    • Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan
  • ,
  • Sheng–Nan Lu

      Affiliations

    • Department of Gastroenterology, Kaohsiung Chang-Gung Memorial Hospital, Kaohsiung, Taiwan
  • ,
  • Chin–Lan Jen

      Affiliations

    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
  • ,
  • Li–Yu Wang

      Affiliations

    • MacKay Medical College, Taipei, Taiwan
  • ,
  • San–Lin You

      Affiliations

    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
  • ,
  • Uchenna H. Iloeje

      Affiliations

    • Research and Development, Bristol-Myers Squibb Company, Wallingford, Connecticut
  • ,
  • Chien–Jen Chen

      Affiliations

    • Genomics Research Center, Academia Sinica, Taipei, Taiwan
    • Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan
    • Corresponding Author InformationReprint requests Address requests for reprints to: Chien-Jen Chen, ScD, Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan. fax: (886) 2-2787-8784
  • ,
  • REVEAL-HBV Study Group

Received 7 January 2010 ,Accepted 12 April 2010.

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 Conflicts of interest These authors disclose the following: Dr Iloeje is an employee of and holds stock in Bristol-Myers Squibb Company. The remaining authors disclose no conflicts.

 Funding This study was supported by research grants from the Department of Health, Executive Yuan, Taipei, Taiwan; Academia Sinica, Taipei, Taiwan; National Health Research Institutes, Chunan, Taiwan; and the Bristol-Myers Squibb Company, Wallingford, CT, to conduct the laboratory tests for this study.The funding sources of this study had no role in the design or conduct of the study, nor did they have any role in the collection, management, analysis, and interpretation of the data as well as the preparation, review, or approval of the manuscript. All data handling and statistical analyses were performed by staff at the National Taiwan University and Academia Sinica. At no time did the funding sources have access to the data.

PII: S0016-5085(10)00656-6

doi: 10.1053/j.gastro.2010.04.048

Gastroenterology
Volume 139, Issue 2 , Pages 474-482 , August 2010