Gastroenterology
Volume 139, Issue 1 , Pages 36-47, July 2010

Regional Brain Activity in Functional Dyspepsia: A H215O-PET Study on the Role of Gastric Sensitivity and Abuse History

  • Lukas Van Oudenhove

      Affiliations

    • Department of Neurosciences, Psychiatry Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    • Department of Pathophysiology, Gastroenterology Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    • Corresponding Author InformationReprint requests Address requests for reprints to: Lukas Van Oudenhove, MD, PhD, Centre for Gastroenterological Research, University Hospital Gasthuisberg, O&N I, bus 701 Herestraat, 49, B-3000 Leuven, Belgium. fax: (016) 345939
  • ,
  • Joris Vandenberghe

      Affiliations

    • Department of Neurosciences, Psychiatry Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Patrick Dupont

      Affiliations

    • Department of Neurosciences, Experimental Neurology Division, Laboratory for Cognitive Neurology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
    • Medical Imaging Research Center, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Brecht Geeraerts

      Affiliations

    • Department of Pathophysiology, Gastroenterology Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Rita Vos

      Affiliations

    • Department of Pathophysiology, Gastroenterology Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Stijn Dirix

      Affiliations

    • Department of Medical Diagnostic Sciences, Nuclear Medicine Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Koen Van Laere

      Affiliations

    • Department of Medical Diagnostic Sciences, Nuclear Medicine Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Guy Bormans

      Affiliations

    • Faculty of Pharmaceutical Sciences, Laboratory for Radiopharmacy, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Dominique Vanderghinste

      Affiliations

    • Faculty of Pharmaceutical Sciences, Laboratory for Radiopharmacy, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Koen Demyttenaere

      Affiliations

    • Department of Neurosciences, Psychiatry Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Benjamin Fischler

      Affiliations

    • Department of Neurosciences, Psychiatry Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium
  • ,
  • Jan Tack

      Affiliations

    • Department of Pathophysiology, Gastroenterology Division, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium

Received 7 January 2010; accepted 8 April 2010. published online 19 April 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This research is supported by a Methusalem grant and an FWO-Vlaanderen (Research Foundation-Flanders) grant to Prof J. Tack. Lukas Van Oudenhove is a postdoctoral research fellow of the FWO-Vlaanderen. Patrick Dupont is supported by Federaal Wetenschapsbeleid belspo IUAP P6/29.

PII: S0016-5085(10)00586-X

doi:10.1053/j.gastro.2010.04.015

Gastroenterology
Volume 139, Issue 1 , Pages 36-47, July 2010