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Gastroenterology
Volume 139, Issue 2
, Pages 530-541
, August 2010
Paired Immunoglobulin-Like Receptor B (PIR-B) Negatively Regulates Macrophage Activation in Experimental Colitis
References
- . The genetics of inflammatory bowel disease. Gastroenterology. 2003;124:521–536
- . Innate immunity in inflammatory bowel disease: a disease hypothesis. J Pathol. 2008;214:260–266
- . Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease. Gut. 1989;30:1362–1370
- Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum. Gut. 1989;30:826–834
- Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. Gut. 1993;34:1705–1709
- Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Dig Dis Sci. 2003;48:408–414
- Blockade of colony stimulating factor-1 (CSF-I) leads to inhibition of DSS-induced colitis. Inflamm Bowel Dis. 2007;13:219–224
- Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus. Am J Physiol Gastrointest Liver Physiol. 2008;294:G770–G777
- . A novel recognition system for MHC class I molecules constituted by PIR. Adv Immunol. 2005;88:161–192
- Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-A and PIR-B. J Exp Med. 1999;189:309–318
- . A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc Natl Acad Sci U S A. 1997;94:5261–5266
- The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. Proc Natl Acad Sci U S A. 1998;95:2446–2451
- PIR-B-deficient mice are susceptible to Salmonella infection. J Immunol. 2008;181:4229–4239
- Paired Ig-like receptors bind to bacteria and shape TLR-mediated cytokine production. J Immunol. 2007;178:4250–4259
- Impaired dendritic cell maturation and increased T(H)2 responses in PIR-B(−/−) mice. Nat Immunol. 2002;3:542–548
- Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis. J Immunol. 2008;181:7390–7399
- Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis. J Allergy Clin Immunol. 2008;122:1200–1207e1
- . Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry A. 2003;55:61–70
- A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils. Blood. 2008;111:5694–5703
- . The immunology of mucosal models of inflammation. Annu Rev Immunol. 2002;20:495–549
- . When signaling pathways collide: positive and negative regulation of Toll-like receptor signal transduction. Immunity. 2008;29:12–20
- Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch. Science. 2004;306:271–275
- Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal. J Exp Med. 1998;187:1355–1360
- Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B. Proc Natl Acad Sci U S A. 1999;96:15086–15090
- . Alterations in colonic barrier function caused by a low sodium diet or ionizing radiation. J Environ Pathol Toxicol Oncol. 2004;23:79–97
- . Activating and inhibitory nature of the murine paired immunoglobulin-like receptor family. Immunol Rev. 2001;181:215–222
- . Paired immunoglobulin-like receptors and their MHC class I recognition. Immunology. 2005;115:433–440
- Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors. J Biol Chem. 1997;272:7320–7327
- The inhibitory receptor PIR-B negatively regulates neutrophil and macrophage integrin signaling. J Immunol. 2004;173:5757–5765
- Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis. J Gastroenterol. 2006;41:318–324
- Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide. J Exp Med. 2001;194:1207–1218
- Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of STAT3 in macrophages and neutrophils. Immunity. 1999;10:39–49
- . The fundamental basis of inflammatory bowel disease. J Clin Invest. 2007;117:514–521
- p38 mitogen-activated protein kinase is activated and linked with TNF-alpha signaling in inflammatory bowel disease. J Immunol. 2002;168:5342–5351
- Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease. FASEB J. 2004;18:1550–1552
- PECAM-1 ligation negatively regulates TLR4 signaling in macrophages. J Immunol. 2007;179:7344–7351
- . The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation and injury. Histol Histopathol. 2007;22:1251–1267
- Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells. Cardiovasc Res. 2005;68:268–277
- Vascular endothelial growth factor-induced endothelial cell proliferation is regulated by interaction between VEGFR-2, SH-PTP1 and eNOS. Microvasc Res. 2006;71:20–31
- LPS-induced down-regulation of signal regulatory protein α contributes to innate immune activation in macrophages. J Exp Med. 2007;204:2719–2731
- Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugs. Rheumatology (Oxford). 2007;46:742–751
- The co-expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium. Am J Pathol. 2002;160:425–431
Conflicts of interest The authors disclose no conflicts.
Funding Supported by an American Heart Association research fellowship (to A.M.), National Institutes of Health grants P01 HL-076383 and R01 AI057803 (to M.E.R.), the CURED and Buckeye Foundations (to M.E.R.), the Food Allergy Project (to M.E.R.), the Crohn's and Colitis Foundation of America Career Development Award (to S.P.H.), and National Institutes of Health grant R01 AI073553-01 (to S.P.H.).
PII: S0016-5085(10)00552-4
doi: 10.1053/j.gastro.2010.04.006
© 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 139, Issue 2
, Pages 530-541
, August 2010

