Gastroenterology
Volume 139, Issue 2 , Pages 644-652.e1 , August 2010

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 2 Controls Energy Balance and Peripheral Insulin Action in Mice

  • Garrett Heinrich

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Sumona Ghosh

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Anthony M. DeAngelis

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Jill M. Schroeder–Gloeckler

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Payal R. Patel

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Tamara R. Castaneda

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Shane Jeffers

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Abraham D. Lee

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physical Therapy at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
  • ,
  • Dae Young Jung

      Affiliations

    • Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts
  • ,
  • Zhiyou Zhang

      Affiliations

    • Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
  • ,
  • Darren M. Opland

      Affiliations

    • Department of Medicine, University of Michigan, Ann Arbor, Michigan
  • ,
  • Martin G. Myers Jr

      Affiliations

    • Department of Medicine, University of Michigan, Ann Arbor, Michigan
  • ,
  • Jason K. Kim

      Affiliations

    • Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    • Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts
  • ,
  • Sonia M. Najjar

      Affiliations

    • The Center for Diabetes and Endocrine Research at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Department of Physiology & Pharmacology at the College of Medicine at the University of Toledo, Health Science Campus, Toledo, Ohio
    • Corresponding Author InformationReprint requests Address requests for reprints to: Sonia M. Najjar, PhD, College of Medicine, University of Toledo, Health Science Campus, 3000 Arlington Avenue, Mail Stop 1008, Toledo, Ohio 43614. fax: (419) 383-2871

Received 20 January 2010 ,Accepted 25 March 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by grants from the National Institutes of Health (R01DK054254 and R01DK083850 to S.M.N., R37DK56731 to M.G.M., and R01-DK80756 and 5-P30-DK32520 [UMass Diabetes Endocrinology Research Center] to J.K.K.), United States Department of Agriculture (USDA 38903-19826 to S.M.N.), the American Diabetes Association (to J.K.K. and M.G.M.), and the American Heart Association (to M.G.M. and G.H.).

PII: S0016-5085(10)00513-5

doi: 10.1053/j.gastro.2010.03.056

Gastroenterology
Volume 139, Issue 2 , Pages 644-652.e1 , August 2010