Gastroenterology
Volume 139, Issue 1 , Pages 154-162.e4, July 2010

Ribavirin Improves Early Responses to Peginterferon Through Improved Interferon Signaling

  • Jordan J. Feld

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • Toronto Western Hospital Liver Centre, University of Toronto, Toronto, Canada
    • ,
  • Glen A. Lutchman

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • Stanford University School of Medicine, Stanford, California
    • ,
  • Theo Heller

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Koji Hara

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Julie K. Pfeiffer

      Affiliations

    • University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Richard D. Leff

      Affiliations

    • School of Pharmacy, Texas Tech University Health Sciences Center & Children's Medical Center, Dallas, Texas
    • ,
  • Claudia Meek

      Affiliations

    • School of Pharmacy, Texas Tech University Health Sciences Center & Children's Medical Center, Dallas, Texas
    • ,
  • Maria Rivera

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Myung Ko

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Christopher Koh

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Yaron Rotman

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Marc G. Ghany

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Vanessa Haynes–Williams

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • Avidan U. Neumann

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • ,
  • T. Jake Liang

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
    • Corresponding Author InformationReprint requests Address requests for reprints to: T. Jake Liang, MD, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 10, Room 9B16, 10 Center Drive, MSC 1800, Bethesda, Maryland 20892-1800. fax: 301-402-0491
    • ,
  • Jay H. Hoofnagle

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland

Received 30 July 2009; accepted 10 March 2010. published online 19 March 2010.

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 Conflicts of interest This author discloses the following: Dr Feld reports being a member of the advisory board for Roche Canada and Schering-Plough Canada. The remaining authors disclose no conflicts.

 Funding This research was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases.

PII: S0016-5085(10)00392-6

doi:10.1053/j.gastro.2010.03.037

Gastroenterology
Volume 139, Issue 1 , Pages 154-162.e4, July 2010

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