Gastroenterology
Volume 138, Issue 5 , Pages 1668-1672.e1 , May 2010

Genome-Wide Association Studies: Present Status and Future Directions

  • Judy H. Cho

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Judy H. Cho, MD, Associate Professor of Medicine and Genetics, Yale University, 333 Cedar St., LMP 1080, New Haven, CT 06510

References 

  1. Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet. 2003;33(suppl):228–237
  2. Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 1989;245:1066–1073
  3. Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461:747–753
  4. A haplotype map of the human genome. Nature. 2005;437:1299–1320
  5. WTCCC. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661–678

 Conflicts of interest The author declares no conflicts.

PII: S0016-5085(10)00383-5

doi: 10.1053/j.gastro.2010.03.028

Gastroenterology
Volume 138, Issue 5 , Pages 1668-1672.e1 , May 2010

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