Gastroenterology
Volume 138, Issue 7 , Pages 2499-2508 , June 2010

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

  • Markus Mair

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Gernot Zollner

      Affiliations

    • Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria
    • ,
  • Doris Schneller

      Affiliations

    • Department of Medicine I, Division of Cancer Research, Medical University of Vienna, Vienna, Austria
    • ,
  • Monica Musteanu

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Peter Fickert

      Affiliations

    • Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria
    • ,
  • Judith Gumhold

      Affiliations

    • Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria
    • ,
  • Christian Schuster

      Affiliations

    • Division of Signal Transduction und Growth Control, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany
    • ,
  • Andrea Fuchsbichler

      Affiliations

    • Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria
    • ,
  • Martin Bilban

      Affiliations

    • Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
    • ,
  • Stefanie Tauber

      Affiliations

    • Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
    • ,
  • Harald Esterbauer

      Affiliations

    • Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
    • ,
  • Lukas Kenner

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Valeria Poli

      Affiliations

    • Department of Genetics, Biology and Biochemistry, University of Turin, Turin, Italy
    • ,
  • Leander Blaas

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Jan Wilhelm Kornfeld

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Emilio Casanova

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • ,
  • Wolfgang Mikulits

      Affiliations

    • Department of Medicine I, Division of Cancer Research, Medical University of Vienna, Vienna, Austria
    • ,
  • Michael Trauner

      Affiliations

    • Laboratory of Experimental and Molecular Hepatology, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria
    • ,
  • Robert Eferl

      Affiliations

    • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
    • Corresponding Author InformationReprint requests Address requests for reprints to: Robert Eferl, MD, Ludwig Boltzmann Institute for Cancer Research, Waehringer Strasse 13a, A-1090 Vienna, Austria. fax: (43) 1-4277-9641

Received 23 February 2009 ,Accepted 16 February 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by the Austrian Science Fund (FWF) grants SFB F28 (R.E. and W.M.), GENAU “Austromouse” (R.E. and E.C.), P18613-B05 (M.T.), and P19118-B05 (M.T.).

PII: S0016-5085(10)00315-X

doi: 10.1053/j.gastro.2010.02.049

Gastroenterology
Volume 138, Issue 7 , Pages 2499-2508 , June 2010

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