« Previous
Next »
Gastroenterology
Volume 138, Issue 5
, Pages 1697-1703.e2
, May 2010
Inflammatory Bowel Disease Confers a Lower Risk of Colorectal Cancer to Females Than to Males
References
- . Die krankhaften geschwulste. Berlin: August Hirschwald; 1863;
- . Inflammation and cancer: back to Virchow?. Lancet. 2001;357:539–545
- . Inflammation and cancer. Nature. 2002;420:860–867
- Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology. 2004;126:451–459
- Trends in cancer mortality sex ratios in Europe, 1950-1989. World Health Stat Q. 1992;45:117–164
- Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science. 2007;317:121–124
- . Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007;317:124–127
- Decreasing time-trends of colorectal cancer in a large cohort of patients with inflammatory bowel disease. Gastroenterology. 2009;136:1561–1567
- . Statistical Databases - Cause of Death Statistics. http://www.socialstyrelsen.se/uppfoljning/statistik/statistikdatabasAccessed March 16, 2010
- The epidemiology of inflammatory bowel disease: a large, population-based study in Sweden. Gastroenterology. 1991;100:350–358
- Incidence of Crohn's disease in Stockholm County 1955–1989. Gut. 1997;41:480–486
- Colonoscopic surveillance in long-standing total ulcerative colitis—a 15-year follow-up study. Gastroenterology. 1990;99:1021–1031
- Survival and cause-specific mortality in inflammatory bowel disease: a population-based cohort study. Gastroenterology. 1996;110:1339–1345
- Incidence of ulcerative colitis in Stockholm County 1955–1979. Scand J Gastroenterol. 1985;20:783–790
- Long-term risk of cancer in ulcerative colitis: a population-based cohort study from Copenhagen County. Clin Gastroenterol Hepatol. 2004;2:1088–1095
- Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer. 2001;91:854–862
- Crohn's disease and cancer: a population-based cohort study. Gastroenterology. 1994;107:1675–1679
- Intestinal cancer risk and mortality in patients with Crohn's disease. Gastroenterology. 1993;105:1716–1723
- Increased risk of large-bowel cancer in Crohn's disease with colonic involvement. Lancet. 1990;336:357–359
- Increased risk of cancer in ulcerative colitis: a population-based cohort study. Am J Gastroenterol. 1999;94:1047–1052
- Ulcerative colitis and colorectal cancer (A population-based study). N Engl J Med. 1990;323:1228–1233
- Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study. Gastroenterology. 1994;107:117–120
- Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol. 1996;8:1179–1183
- Colorectal cancer prevention in ulcerative colitis: a case-control study. Aliment Pharmacol Ther. 2000;14:145–153
- . Statistics Sweden Web site http://www.scb.se/Accessed December 16, 2009
- Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis. Am J Gastroenterol. 2001;96:2929–2933
- Patient nonadherence to medication in inflammatory bowel disease. Am J Gastroenterol. 2003;98:1535–1544
- Predictors of medication adherence in inflammatory bowel disease. Am J Gastroenterol. 2007;102:1417–1426
- . Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis. Am J Med. 1999;106:574–582
- . Do reproductive factors influence colorectal cancer survival?. J Clin Epidemiol. 1995;48:1119–1122
- Hormone replacement therapy is associated with lower risk of adenomatous polyps of the large bowel: the Minnesota Cancer Prevention Research Unit Case-Control Study. Cancer Epidemiol Biomarkers Prev. 1996;5:779–784
- Estrogen plus progestin and colorectal cancer in postmenopausal women. N Engl J Med. 2004;350:991–1004
- Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet. 1994;7:536–540
- Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer. Cancer Res. 2001;61:126–130
- Ulcerative colitis-associated colorectal cancer is frequently associated with the microsatellite instability pathway. Dis Colon Rectum. 2008;51:1387–1394
- Natural history of severe ulcerative colitis in a community-based health plan. Clin Gastroenterol Hepatol. 2008;6:999–1003
- Gender-related differences in the clinical course of Crohn's disease. Am J Gastroenterol. 2001;96:1541–1546
- Oral contraceptive use and the clinical course of Crohn's disease: a prospective cohort study. Gut. 1999;45:218–222
- . Hormonal replacement therapy after menopause is protective of disease activity in women with inflammatory bowel disease. Am J Gastroenterol. 2008;103:1193–1196
- Risk of intestinal cancer in inflammatory bowel disease: a population-based study from Olmsted County, Minnesota. Gastroenterology. 2006;130:1039–1046
View this article's video abstract at www.gastrojournal.org.
Conflicts of interest The authors disclose no conflicts.
Funding Supported by the Swedish Medical Association, the Swedish Cancer Society.
PII: S0016-5085(10)00179-4
doi: 10.1053/j.gastro.2010.02.007
© 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Gastroenterology
Volume 138, Issue 5
, Pages 1697-1703.e2
, May 2010

