Gastroenterology
Volume 138, Issue 5 , Pages 1673-1680.e1 , May 2010

Does Capsule Endoscopy Improve Outcomes in Obscure Gastrointestinal Bleeding? Randomized Trial Versus Dedicated Small Bowel Radiography

  • Loren Laine

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Loren Laine, GI Division, Keck School of Medicine, 2025 Zonal Avenue, Los Angeles, CA 90033. fax: (323) 441-8352
    • ,
  • Amandeep Sahota
    • ,
  • Abbid Shah

Received 11 November 2009 ,Accepted 25 January 2010.

References 

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  2. Raju GS, Gerson L, Das A, et al. American Gastroenterological Association (AGA) technical review on obscure gastrointestinal bleeding. Gastroenterology. 2007;133:1697–1717
  3. Triester SL, Leighton JA, Leontiadis GI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol. 2005;100:2407–2418
  4. Morris DW, Levine GM, Soloway RD, et al. Prospective, randomized study of diagnosis and outcome in acute upper-gastrointestinal bleeding: endoscopy versus conventional radiography. Am J Dig Dis. 1975;20:1103–1109
  5. Dronfield MW, Langman MJ, Atkinson M, et al. Outcome of endoscopy and barium radiography for acute upper gastrointestinal bleeding: controlled trial in 1037 patients. Br Med J. 1982;284:545–548
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  8. Ott DJ, Chen YM, Gelfand DW, et al. Detailed per-oral small bowel examination vs. enteroclysis (Part II: radiographic accuracy). Radiology. 1985;155:31–34
  9. Albert JG, Schulbe R, Hahn L, et al. Impact of capsule endoscopy on outcome in mid-intestinal bleeding: a multicentre cohort study in 285 patients. Eur J Gastroenterol Hepatol. 2008;20:971–977
  10. Estevez E, Gonzalez-Conde B, Vazquez-Iglesias JL, et al. Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding. Eur J Gastroenterol Hepatol. 2006;18:881–888
  11. Neu B, Ell C, May A, et al. Capsule endoscopy versus standard tests in influencing management of obscure digestive bleeding: results from a German multicenter trial. Am J Gastroenterol. 2005;100:1736–1742
  12. Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology. 2004;126:643–653
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  14. Haghighi D, Zuccaro G, Vargo J, et al. Comparison of capsule endoscopy (CE) findings of healthy subjects (HS) to an obscure gastrointestinal bleeding (OGIB) patient population [abstract]. Gastrointest Endosc. 2005;61:AB104
  15. Lai LH, Wong GLH, Chow DKL, et al. Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am J Gastroenterol. 2006;101:1224–1228
  16. McDonald J, Porter V, McNamara D. Negative capsule endoscopy in patients with obscure GI bleeding predicts low rebleeding rates. Gastrointes Endosc. 2008;68:1122–1127
  17. Sun B, Rajan E, Cheng S, et al. Diagnostic yield and therapeutic impact of double-balloon enteroscopy in a large cohort of patients with obscure gastrointestinal bleeding. Am J Gastroenterol. 2006;101:2011–2015
  18. Carey EJ, Leighton JA, Heigh RI, et al. A single-center experience of 260 consecutive patients undergoing capsule endoscopy for obscure gastrointestinal bleeding. Am J Gastroenterol. 2007;102:89–95

 This article has an accompanying continuing medical education activity on page e11. Learning Objective: Upon completion of reading this article, successful learners will be able to discuss the diagnostic evaluation of obscure gastrointestinal bleeding.

 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by a grant from the American Society for Gastrointestinal Endoscopy Wireless Video Capsule Endoscopy Clinical Research Award (Project no. 16; 2004).

PII: S0016-5085(10)00156-3

doi: 10.1053/j.gastro.2010.01.047

Gastroenterology
Volume 138, Issue 5 , Pages 1673-1680.e1 , May 2010

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