Gastroenterology
Volume 138, Issue 5 , Pages 1854-1862.e1, May 2010

Aberrant DNA Methylation in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency

  • Ajay Goel

      Affiliations

    • Division of Gastroenterology, Department of Medicine, Baylor University, Medical Center, Dallas, Texas
    • Corresponding Author InformationAjay Goel, PhD, Gastointestinal Research Lab, Baylor University Medical Center, 3500 Gaston Avenue, Suite H-250, Dallas, Texas 75246. fax: (214) 818-9292
    • ,
  • Rosa M. Xicola

      Affiliations

    • Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, Illinois
    • ,
  • Thuy–Phuong Nguyen

      Affiliations

    • Division of Gastroenterology, Department of Medicine, Baylor University, Medical Center, Dallas, Texas
    • ,
  • Brian J. Doyle

      Affiliations

    • Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, Illinois
    • ,
  • Vanessa R. Sohn

      Affiliations

    • Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, Illinois
    • ,
  • Prathap Bandipalliam

      Affiliations

    • Division of Population Sciences, Dana-Farber Cancer Institute and Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts
    • ,
  • Laura S. Rozek

      Affiliations

    • School of Public Health, University of Michigan, Ann Arbor, Michigan
    • ,
  • Josep Reyes

      Affiliations

    • Gastroenterology Department, Hospital Comarcal Inca, Mallorca, Spain
    • ,
  • Carmen Cordero

      Affiliations

    • Gastroenterology Department, Hospital Virgen del Rocio, Sevilla, Spain
    • ,
  • Francesc Balaguer

      Affiliations

    • Division of Gastroenterology, Department of Medicine, Baylor University, Medical Center, Dallas, Texas
    • ,
  • Antoni Castells

      Affiliations

    • Gastroenterology Department, Hospital Clinic, IDIBAPS, CIBERehd, University of Barcelona, Barcelona, Catalonia, Spain
    • ,
  • Rodrigo Jover

      Affiliations

    • Gastroenterology Unit, Hospital General Univ, Alicante, Spain
    • ,
  • Montserrat Andreu

      Affiliations

    • Gastroenterology Department, Hospital del Mar, Barcelona, Catalonia, Spain
    • ,
  • Sapna Syngal

      Affiliations

    • Division of Population Sciences, Dana-Farber Cancer Institute and Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts
    • ,
  • C. Richard Boland

      Affiliations

    • Division of Gastroenterology, Department of Medicine, Baylor University, Medical Center, Dallas, Texas
    • ,
  • Xavier Llor

      Affiliations

    • Department of Medicine and Cancer Center, University of Illinois at Chicago, Chicago, Illinois
    • Corresponding Author InformationReprint requests Address requests for reprints to: Xavier Llor, MD, PhD, Department of Medicine and Cancer Center, University of Illinois at Chicago, 840 South Wood Street (M/C 716), Chicago, Illinois 60612. fax: (312) 996-5103

Received 12 October 2009; accepted 8 January 2010. published online 25 January 2010.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by the Sirazi Foundation, Raymond Cole Memorial Foundation, and an internal grant from the Department of Medicine and the Cancer Center of the University of Illinois at Chicago (X.L.); National Institutes of Health grants CA72851 and funds from the Baylor Research Institute (C.R.B. and A.G.); and a grant from the Spanish Ministerio de Ciencia e Innovación (SAF 07-64873 to A.C.).

PII: S0016-5085(10)00102-2

doi:10.1053/j.gastro.2010.01.035

Gastroenterology
Volume 138, Issue 5 , Pages 1854-1862.e1, May 2010

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