Gastroenterology
Volume 138, Issue 5 , Pages 1783-1789 , May 2010

Altered Brain Structure in Irritable Bowel Syndrome: Potential Contributions of Pre-Existing and Disease-Driven Factors

  • Udi Blankstein

      Affiliations

    • Division of Brain, Imaging and Behaviour–Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    • Institute of Medical Science, University Health Network, Toronto, Ontario, Canada
  • ,
  • Jerry Chen

      Affiliations

    • Division of Brain, Imaging and Behaviour–Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    • Institute of Medical Science, University Health Network, Toronto, Ontario, Canada
  • ,
  • Nicholas E. Diamant

      Affiliations

    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  • ,
  • Karen D. Davis

      Affiliations

    • Division of Brain, Imaging and Behaviour–Systems Neuroscience, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
    • Institute of Medical Science, University Health Network, Toronto, Ontario, Canada
    • Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests Address requests for reprints to: Karen D. Davis, PhD, Division of Brain, Imaging and Behaviour-Systems Neuroscience, Toronto Western Research Institute, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Room MP14-306, Toronto, Ontario, Canada M5T 2S8. fax: (416) 603-5745

Received 26 August 2009 ,Accepted 21 December 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by the Canadian Institutes of Health Research (CIHR MOP 53304) and by the Purdue Pharma OGSST scholarship and CIHR Strategic Training Program: Pain Molecules to Community Fellowship (to U.B.).

PII: S0016-5085(09)02240-9

doi: 10.1053/j.gastro.2009.12.043

Gastroenterology
Volume 138, Issue 5 , Pages 1783-1789 , May 2010