Gastroenterology
Volume 138, Issue 3 , Pages 1012-1021.e5 , March 2010

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro

  • Andres I. Roig

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
    • Department of Medicine, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Ugur Eskiocak

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Suzie K. Hight

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Sang Bum Kim

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Oliver Delgado

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Rhonda F. Souza

      Affiliations

    • Department of Medicine, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
    • Veterans Affairs North Texas Health Care System, Dallas, Texas
  • ,
  • Stuart J. Spechler

      Affiliations

    • Department of Medicine, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
    • Veterans Affairs North Texas Health Care System, Dallas, Texas
  • ,
  • Woodring E. Wright

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
  • ,
  • Jerry W. Shay

      Affiliations

    • Department of Cell Biology, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas
    • Corresponding Author InformationReprint requests Address requests for reprints to: Jerry W. Shay, PhD, Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390. fax: (214) 648-8694

Received 19 August 2009 ,Accepted 20 November 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by NASA grant no. NNXO8BA54G and NNX09AU95G to J.W.S., and T32 CA124334 and American Gastroenterology Association Fellow to Faculty Transition Award to A.I.R.

PII: S0016-5085(09)02104-0

doi: 10.1053/j.gastro.2009.11.052

Gastroenterology
Volume 138, Issue 3 , Pages 1012-1021.e5 , March 2010