Genome-Wide Association Analysis in Primary Sclerosing Cholangitis

Karlsen, Tom H.; Franke, Andre; Melum, Espen; Kaser, Arthur; Hov, Johannes Roksund; Balschun, Tobias; Lie, Benedicte A.; Bergquist, Annika; Schramm, Christoph; Weismüller, Tobias J.; Gotthardt, Daniel; Rust, Christian; Philipp, Eva E.R.; Fritz, Teresa; Henckaerts, Liesbet; Weersma, Rinse K.; Stokkers, Pieter; Ponsioen, Cyriel Y.; Wijmenga, Cisca; Sterneck, Martina; Nothnagel, Michael; Hampe, Jochen; Teufel, Andreas; Runz, Heiko; Rosenstiel, Philip; Stiehl, Adolf; Vermeire, Severine; Beuers, Ulrich; Manns, Michael P.; Schrumpf, Erik; Boberg, Kirsten Muri; Schreiber, Stefan

doi:10.1053/j.gastro.2009.11.046

« Previous Next »Gastroenterology
Volume 138, Issue 3 , Pages 1102-1111, March 2010

Genome-Wide Association Analysis in Primary Sclerosing Cholangitis

Tom H. Karlsen
- Medical Department, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway
- Reprint requests Address requests for reprints to: Tom H. Karlsen, MD, PhD, Medical Department, Rikshospitalet University Hospital, 0027 Oslo, Norway. fax: (47) 23074869
Andre Franke
- Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
Espen Melum
- Medical Department, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway
Arthur Kaser
- Department of Gastroenterology and Hepatology, Innsbruck Medical University, Innsbruck, Austria
Johannes Roksund Hov
- Medical Department, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway
Tobias Balschun
- Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
Benedicte A. Lie
- Institute of Immunology, Rikshospitalet University Hospital, Oslo, Norway
Annika Bergquist
- Department of Gastroenterology and Hepatology, Karolinska University Hospital Huddinge, Stockholm, Sweden
Christoph Schramm
- 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Tobias J. Weismüller
- Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
Daniel Gotthardt
- Department of Medicine, University Hospital of Heidelberg, Heidelberg, Germany
Christian Rust
- Department of Medicine 2, Grosshadern, University of Munich, Munich, Germany
Eva E.R. Philipp
- Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
Teresa Fritz
- Department of Gastroenterology and Hepatology, Innsbruck Medical University, Innsbruck, Austria
Liesbet Henckaerts
- Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Rinse K. Weersma
- Department of Gastroenterology and Hepatology, University Medical Center Groningen and University of Groningen, The Netherlands
Pieter Stokkers
- Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Cyriel Y. Ponsioen
- Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Cisca Wijmenga
- Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
Martina Sterneck
- 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Michael Nothnagel
- Institute of Medical Informatics and Statistics, Christian-Albrechts-University, Kiel, Germany
Jochen Hampe
- Department for General Internal Medicine, Christian-Albrechts-University, Kiel, Germany
Andreas Teufel
- 1st Department of Medicine, University of Mainz, Mainz, Germany
Heiko Runz
- Department of Human Genetics, University Hospital of Heidelberg, Heidelberg, Germany
Philip Rosenstiel
- Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
Adolf Stiehl
- Department of Medicine, University Hospital of Heidelberg, Heidelberg, Germany
Severine Vermeire
- Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Ulrich Beuers
- Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Michael P. Manns
- Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
Erik Schrumpf
- Medical Department, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway
Kirsten Muri Boberg
- Medical Department, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway
Stefan Schreiber
- Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
- Department for General Internal Medicine, Christian-Albrechts-University, Kiel, Germany

Received 10 August 2009; accepted 18 November 2009. published online 30 November 2009.

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Conflicts of interest The authors disclose no conflicts.

Funding The study was supported by the German Ministry of Education and Research (BMBF) through the National Genome Research Network and the PopGen biobank (www.popgen.de). The project received infrastructure support through the DFG excellence cluster “Inflammation at Interfaces” (www.inflammation-at-interfaces.de) and the Norwegian PSC research center (www.rikshospitalet.no/nopsc).

PII: S0016-5085(09)02063-0

doi:10.1053/j.gastro.2009.11.046

« Previous Next »Gastroenterology
Volume 138, Issue 3 , Pages 1102-1111, March 2010

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