Gastroenterology
Volume 138, Issue 1 , Pages 46-51.e1 , January 2010

Proteomic Approaches to Cancer Biomarkers

  • Kenneth E. Hung

      Affiliations

    • Department of Medicine, Tufts Medical Center, Boston, Massachusetts
    • Corresponding Author InformationReprint requests Address requests for reprints to: Kenneth E. Hung, MD, PhD, Division of Gastroenterology, Tufts Medical Center, 750 Washington Street, Box 233, Boston, Massachusetts 02111. fax: (617) 636-4505
    • ,
  • Kenneth H. Yu

      Affiliations

    • Centers for Cancer Pharmacology and Excellence in Environmental Toxicology and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71–96
  2. Gold P, Freedman SO. Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. J Exp Med. 1965;121:439–462
  3. Koprowski H, Herlyn M, Steplewski Z, et al. Specific antigen in serum of patients with colon carcinoma. Science. 1981;212:53–55
  4. Abelev GI, Perova SD, Khramkova NI, et al. Production of embryonal alpha-globulin by transplantable mouse hepatomas. Transplantation. 1963;1:174–180
  5. Petricoin EF, Ardekani AM, Hitt BA, et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet. 2002;359:572–577

 Conflicts of interest The authors disclose no conflicts.

PII: S0016-5085(09)02037-X

doi: 10.1053/j.gastro.2009.11.020

Gastroenterology
Volume 138, Issue 1 , Pages 46-51.e1 , January 2010

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