Gastroenterology
Volume 138, Issue 2 , Pages 562-572.e2, February 2010

Interleukin-1β Promotes Gastric Atrophy Through Suppression of Sonic Hedgehog

  • Meghna Waghray

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • ,
  • Yana Zavros

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • ,
  • Milena Saqui–Salces

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • ,
  • Mohamad El–Zaatari

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • ,
  • C. Bharath Alamelumangapuram

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan
    • Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan
    • ,
  • Andrea Todisco

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • ,
  • Kathryn A. Eaton

      Affiliations

    • Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan
    • ,
  • Juanita L. Merchant

      Affiliations

    • Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan
    • Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan
    • Corresponding Author InformationReprint requests Address requests for reprints to: Juanita L. Merchant, MD, PhD, 2051 BSRB, 109 Zina Pitcher Place, Ann Arbor, Michigan 48109-2200. fax: (734) 763-4686

Received 12 March 2009; accepted 22 October 2009. published online 02 November 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by NIH grants P01 DK62041 (J.L.M.) and R56 DK058312-06A2 (A.T.).

PII: S0016-5085(09)01940-4

doi:10.1053/j.gastro.2009.10.043

Refers to article:

  • Sonic Hedgehog: A Link Between Inflammation, Gastric Atrophy, and Acid Suppression? , 23 December 2009

    Willemijn A. Van Dop, Gijs R. Van Den Brink
    Gastroenterology February 2010 (Vol. 138, Issue 2, Pages 426-429)

Gastroenterology
Volume 138, Issue 2 , Pages 562-572.e2, February 2010

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