Gastroenterology
Volume 137, Issue 6 , Pages 2030-2040.e5 , December 2009

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

  • Michael Scharl

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
    • ,
  • Gisela Paul

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • ,
  • Achim Weber

      Affiliations

    • Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland
    • ,
  • Barbara C. Jung

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • ,
  • Michael J. Docherty

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • ,
  • Martin Hausmann

      Affiliations

    • Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
    • ,
  • Gerhard Rogler

      Affiliations

    • Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
    • ,
  • Kim E. Barrett

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • ,
  • Declan F. McCole

      Affiliations

    • Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California
    • Corresponding Author InformationReprint requests Address requests for reprints to: Declan F. McCole, PhD, Division of Gastroenterology, School of Medicine, University of California, San Diego, 9500 Gilman Drive-0063, La Jolla, California 92093-0063. fax: (858) 534 3338

Received 11 August 2008 ,Accepted 31 July 2009.

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 Conflicts of interest The authors disclose no conflicts.

 FundingSupported by a Crohn's and Colitis Foundation of America Senior Research Award (to D.F.M.); a Jon I. Isenberg Award (to D.F.M.); grants from the German Research Foundation (DFG) (to M.S. and G.P.); NIH grant DK28305 (to K.E.B.); an unrestricted research gift from the Shape-Up Settlement fund (to K.E.B.); and by the University of California, San Diego, Digestive Diseases Research Development Center (DK080506).

PII: S0016-5085(09)01757-0

doi: 10.1053/j.gastro.2009.07.078

Gastroenterology
Volume 137, Issue 6 , Pages 2030-2040.e5 , December 2009

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