Gastroenterology
Volume 137, Issue 5 , Pages 1559-1562 , November 2009

Synchronous Colorectal Cancer: Not Just Bad Luck?

  • Barbara A. Leggett

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Professor Barbara Leggett, MD, Dept of Gastroenterology and Hepatology, Level 9 Ned Hanlon Building, Royal Brisbane and Womens Hospital, Herston, QLD, 4029, Australia
    • ,
  • Daniel L. Worthley

  • Image Result

    Relative contributions of different pathways of colorectal carcinogenesis to the occurrence of synchronous cancer. Block pink to red shading represents the relative genetic contribution and the red do

    Relative contributions of different pathways of colorectal carcinogenesis to the occurrence of synchronous cancer. Block pink to red shading represents the relative genetic contribution and the red dots depict superimposed patchy environmental events and the typical distribution of pathology. CIN, chromosomal instability; MSI, microsatellite instability; CIMP, CpG island methylator phenotype; MSS, microsatellite stable; DALM, dysplasia-associated lesion or mass.

 Conflicts of interest The authors disclose no conflicts.

PII: S0016-5085(09)01666-7

doi: 10.1053/j.gastro.2009.09.025

Gastroenterology
Volume 137, Issue 5 , Pages 1559-1562 , November 2009

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