Gastroenterology
Volume 138, Issue 1 , Pages 285-293 , January 2010

Endogenous IGF-I and αVβ3 Integrin Ligands Regulate Increased Smooth Muscle Hyperplasia in Stricturing Crohn's Disease

  • Robert S. Flynn

      Affiliations

    • Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Karnam S. Murthy

      Affiliations

    • Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • John R. Grider

      Affiliations

    • Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • John M. Kellum

      Affiliations

    • Department of Surgery, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • John F. Kuemmerle

      Affiliations

    • Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • Department of Physiology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia
    • Corresponding Author InformationReprint requests Address requests for reprints to: John F. Kuemmerle, MD, Division of Gastroenterology, Medical College of Virginia Campus, Virginia Commonwealth University, PO Box 980341, Richmond, Virginia 23298-0341. fax: (804) 828-2500

Received 17 February 2009 ,Accepted 3 September 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by grant DK49691 from the National Institutes of Diabetes and Digestive and Kidney Diseases.

PII: S0016-5085(09)01566-2

doi: 10.1053/j.gastro.2009.09.003

Gastroenterology
Volume 138, Issue 1 , Pages 285-293 , January 2010

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