Gastroenterology
Volume 137, Issue 5, Supplement , Pages S1-S6 , November 2009

Micronutrients in Parenteral Nutrition: Too Little or Too Much? The Past, Present, and Recommendations for the Future

  • Alan L. Buchman

      Affiliations

    • Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Evanston, Illinois
    • Corresponding Author InformationCorrespondence Address correspondence to: Alan L. Buchman, MD, MSPH, Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair St., Suite 1400, Chicago, Illinois 60611. fax: (312) 695-3999
    • ,
  • Lyn J. Howard

      Affiliations

    • Albany Medical College, Oley Foundation, Albany, New York
    • ,
  • Peggi Guenter

      Affiliations

    • American Society for Parenteral and Enteral Nutrition, Silver Spring, Maryland
    • ,
  • Reid A. Nishikawa

      Affiliations

    • Nutrishare, Inc, Elk Grove, California
    • ,
  • Charlene W. Compher

      Affiliations

    • School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • Kelly A. Tappenden

      Affiliations

    • University of Illinois at Urbana-Champaign, Urbana, Illinois

References 

  1. Jeejeebhoy KN, Zohrab WJ, Langer B, et al. Total parenteral nutrition at home for 23 months, without complications and with good rehabilitation. Gastroenterology. 1973;65:811–820
  2. Broviac JN, Scribner BH. Prolonged parenteral nutrition in the home. Surg Gynecol Obstet. 1974;139:24–28
  3. Fleming CR, McGill DB, Berkerer S. Home parenteral nutrition as primary therapy in patients with extensive Crohn's disease of the bowel and malnutrition. Gastroenterology. 1977;73:1077–1081
  4. Ladefoged K, Jaum S. Long term parenteral nutrition. Br Med J. 1978;2:262–266
  5. The Oley Foundation for Home Parenteral & Enteral Nutrition Web site. Oley Patient Profiles. www.oley.org/oley_profilesAccessed September 17, 2009
  6. Okada A, Takagi Y, IIeakura T, et al. Skin lesions during intravenous hyperalimentation: zinc deficiency. Surgery. 1976;80:629–635
  7. Kay RG, Tasman-Jones C, Pybus J, et al. A syndrome of acute zinc deficiency during total parenteral alimentation in man. Ann Surg. 1976;183:331–340
  8. Heller RM, Kirchner SA, O'Neill JA, et al. Skeletal changes of copper deficiency in infants receiving prolonged parenteral nutrition. J Pediatr. 1978;92:947–949
  9. Karpel JT, Peden VH. Copper deficiency in long term parenteral nutrition. J Pediatr. 1972;80:32–36
  10. Vilter RW, Bozian RC, Hess EV, et al. Manifestations of copper deficiency in patient with systemic sclerosis on intravenous hyperalimentation. N Engl J Med. 1974;29:188–193
  11. Jeejeebhoy KN, Chu RC, Marliss EB, et al. Chromium deficiency, glucose intolerance and neuropathy reversed by chromium supplementation in a patient receiving long term total parenteral nutrition. Am J Clin Nutr. 1977;30:535–538
  12. Freund H, Atamian J, Fisher JE. Chromium deficiency during total parenteral nutrition. JAMA. 1979;241:496–498
  13. van Rij AM, Thompson CD, McKenzie JM, et al. Selenium deficiency in total parenteral nutrition. Am J Clin Nutr. 1979;32:2076–2085
  14. Federal Register. July 27, 172.
  15. Department of Foods and Nutrition, American Medical Association. Guidelines for multivitamin preparations for parenteral use. Chicago, IL: Department of Foods and Nutrition, American Medical Association.
  16. Multivitamin preparations for parenteral use (A statement by the Nutrition Advisory Group). JPEN J Parenter Enteral Nutr. 1979;3:258–262
  17. Federal Register. April 20, 2000.
  18. Guidelines for the use of vitamins, trace elements, calcium, magnesium, phosphorus in infants and children receiving total parenteral nutrition: report of the Subcommittee on Pediatric Parenteral Nutrient Requirements from the Committee on Clinical Practice issues of the American Society for Clinical Nutrition. Am J Clin Nutr. 1988;48:1324–1342
  19. National Research Council, Food and Nutrition Board. Recommended dietary allowances. 8th ed.. Washington, DC: National Academy Science; 1974;
  20. Shils ME, Baker H, Frank O. Blood vitamin levels of long term adult home total parenteral nutrition patients: the efficacy of the AMA-FDA parenteral multivitamin formulation. JPEN J Parenter Enteral Nutr. 1985;9:179–188
  21. Howard L, Bigaouette J, Chu R, et al. Water soluble vitamin requirements in home parenteral nutrition patients. Am J Clin Nutr. 1983;37:421–428
  22. Labadarios D, O'Keefe S, Dicker J, et al. Plasma vitamin levels in patients on prolonged total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1988;12:205–211
  23. Dempsey DT, Mullen JL, Rombeau JL, et al. Treatment effects of parenteral vitamins in total parenteral nutrition patients. JPEN J Parenter Enteral Nutr. 1987;11:229–237
  24. Inculet RI, Norton JA, Nichoalds GE, et al. Water-soluble vitamins in cancer patients on parenteral nutrition: a prospective study. JPEN J Parenter Enteral Nutr. 1987;11:243–249
  25. Stromberg P, Shenkin A, Campbell RA, et al. Vitamin status during total parenteral nutrition. JPEN J Parenter Enteral Nutr. 1981;5:295–299
  26. Hands LJ, Royle GT, Kettlewell MG. Vitamin K requirements in patients receiving total parenteral nutrition. Br J Surg. 1985;72:665–667
  27. Greene HL, Phillips BL, Franck L, et al. Persistently low blood retinol levels during and after parenteral feeding of very low birth weight infants: examination of losses into intravenous administration sets and a method of prevention by addition to a lipid emulsion. Pediatrics. 1987;79:894–900
  28. Shenai JP, Chytil F, Stahlman MT. Vitamin A status of neonates with bronchopulmonary dysplasia. Pediatr Res. 1985;19:185–187
  29. Guidelines for essential trace element preparations for parenteral use. JAMA. 1979;24:2051–2054
  30. Guidelines for essential trace element preparations for parenteral use (A statement by the Nutrition Advisory Group). JPEN J Parenter Enteral Nutr. 1979;3:263–267
  31. Shils ME, White PL. Working conference on parenteral trace elements: sponsored by NY Acad Med and AMA. Bull N Y Acad Med. 1984;60:115–212
  32. Shils ME, Brown RO. Parenteral nutrition. In:  Shils ME,  Olsen JA,  Shike M editor. Modern nutrition in health and disease. 9th ed.. Philadelphia, PA: Lea & Febiger; 1994;
  33. Safe practices for parenteral nutrition. JPEN J Parenter Enteral Nutr. 1998;22:49–66
  34. Revision of safe practices for parenteral nutrition. JPEN J Parenter Enteral Nutr. 2006;30:177
  35. Keshan Disease Research Group. Observations on effect of sodium selenite in prevention of Keshan disease. Chin Med J. 1979;92:471–476
  36. Skike M, Roule M, Kurian R, et al. Copper metabolism and requirement in total parenteral nutrition. Gastroenterology. 1981;81:290–297
  37. Moukarzel AA, Song MK, Buchman AL, et al. Excessive chromium intake in children receiving total parenteral nutrition. Lancet. 1992;339:385–388
  38. Fell JM, Reynolds AP, Meadows N, et al. Manganese toxicity in children receiving long term parenteral nutrition. Lancet. 1996;347:1218–1221
  39. Reynolds CR. Manganese requirement and toxicity in patients on home parenteral nutrition. Clin Nutr. 1998;17:227–230
  40. Howard L, Ashley C, Lyon D, et al. Autopsy tissue trace elements in 8 long-term parenteral nutrition patients who received the current U.S. Food and Drug Administration Formulation. JPEN J Parenter Enteral Nutr. 2007;31:388–396

 Conflicts of interest Dr Buchman shares in the intellectual property rights to intravenous choline licensed to Bioniche Pharma USA. Dr Buchman declares no other relationship with Bioniche Pharma. The remaining authors disclose no conflicts.

PII: S0016-5085(09)01560-1

doi: 10.1053/j.gastro.2009.09.001

Gastroenterology
Volume 137, Issue 5, Supplement , Pages S1-S6 , November 2009

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