Gastroenterology
Volume 137, Issue 6 , Pages 1954-1962 , December 2009

Childhood Trauma Is Associated With Hypothalamic-Pituitary-Adrenal Axis Responsiveness in Irritable Bowel Syndrome

  • Elizabeth J. Videlock

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Mopelola Adeyemo

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Arlene Licudine

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Miyoshi Hirano

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Gordon Ohning

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California
    • ,
  • Minou Mayer

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Emeran A. Mayer

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California
    • Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, California
    • Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, California
    • Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, California
    • ,
  • Lin Chang

      Affiliations

    • Center for Neurobiology of Stress, David Geffen School of Medicine, University of California, Los Angeles, California
    • Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California
    • Corresponding Author InformationReprint requests Address requests for reprints to: Lin Chang, MD, Center for Neurobiology of Stress, 10833 Le Conte Avenue, CHS 47-122, Los Angeles, California 90095-7378. fax: (310) 206-3343

Received 20 May 2009 ,Accepted 21 August 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by National Institutes of Health grants P50 DK64539 (E.A.M., L.C.), R01 AR46122 (L.C.), R24 AT002681 (E.A.M.), and GCRC M01-RR00865.

PII: S0016-5085(09)01548-0

doi: 10.1053/j.gastro.2009.08.058

Gastroenterology
Volume 137, Issue 6 , Pages 1954-1962 , December 2009

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