Gastroenterology
Volume 137, Issue 5 , Pages 1785-1794, November 2009

Transmembrane and Soluble Isoforms of Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulate Distinct Processes in the Pancreas

  • Kevin C. Ray

      Affiliations

    • Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Stacy A. Blaine

      Affiliations

    • Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • M. Kay Washington

      Affiliations

    • Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Ada H. Braun

      Affiliations

    • Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    • Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Amar B. Singh

      Affiliations

    • Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Raymond C. Harris

      Affiliations

    • Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    • Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Paul A. Harding

      Affiliations

    • Department of Zoology, Miami University, Oxford, Ohio
    • ,
  • Robert J. Coffey

      Affiliations

    • Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    • Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    • ,
  • Anna L. Means

      Affiliations

    • Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee
    • Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    • Corresponding Author InformationReprint requests Address requests for reprints to: Anna L. Means, PhD, Division of Surgical Oncology, Vanderbilt University Medical Center, 10445 MRB IV, 2213 Garland Avenue, Nashville, Tennessee 37232-0443. fax: (615)-343-1591

Received 5 December 2008; accepted 31 July 2009. published online 17 August 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by National Institutes of Health grants CA98322 (A.L.M.), CA84239 (R.J.C. and A.L.M.), CA95103 (R.J.C.), CA46413 (R.J.C.), and DK58404 (M.K.W.) and with the support of the Vanderbilt ES/Transgenic Core, Vanderbilt Hormone Assay Core, and the Vanderbilt Cell Imaging Shared Resource.

PII: S0016-5085(09)01399-7

doi:10.1053/j.gastro.2009.07.067

Gastroenterology
Volume 137, Issue 5 , Pages 1785-1794, November 2009

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