Gastroenterology
Volume 137, Issue 5 , Pages 1795-1804 , November 2009

Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

  • Charis L. Johnson

      Affiliations

    • Children's Health Research Institute, London, Ontario
    • Department of Paediatrics, The University of Western Ontario, London, Ontario
  • ,
  • Jacqueline Y. Weston

      Affiliations

    • Children's Health Research Institute, London, Ontario
    • Department of Physiology & Pharmacology, The University of Western Ontario, London, Ontario
    • Department of Paediatrics, The University of Western Ontario, London, Ontario
  • ,
  • Sami A. Chadi

      Affiliations

    • Children's Health Research Institute, London, Ontario
    • Department of Paediatrics, The University of Western Ontario, London, Ontario
  • ,
  • Elena N. Fazio

      Affiliations

    • Children's Health Research Institute, London, Ontario
    • Department of Physiology & Pharmacology, The University of Western Ontario, London, Ontario
    • Department of Paediatrics, The University of Western Ontario, London, Ontario
  • ,
  • Murray W. Huff

      Affiliations

    • Department of Biochemistry, The University of Western Ontario, London, Ontario
  • ,
  • Alexei Kharitonenkov

      Affiliations

    • Lilly Research Laboratories, Division of Eli Lilly, Indianapolis, Indiana
  • ,
  • Anja Köester

      Affiliations

    • Lilly Research Laboratories, Division of Eli Lilly, Indianapolis, Indiana
  • ,
  • Christopher L. Pin

      Affiliations

    • Children's Health Research Institute, London, Ontario
    • Department of Physiology & Pharmacology, The University of Western Ontario, London, Ontario
    • Department of Paediatrics, The University of Western Ontario, London, Ontario
    • Corresponding Author InformationReprint requests Address requests for reprints to: Christopher Pin, PhD, Department of Paediatrics, The University of Western Ontario, Children's Health Research Institute, 5th Floor, Victoria Research Laboratories, London, Ontario, Canada, N6C 2V5. fax: (519) 685-8186

Received 22 July 2008 ,Accepted 30 July 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by operating grants from the Canadian Institutes of Health Research (CIHR; CP-MOP 53083), Children's Health Research Institute, and Lawson Health Research Institute; by an Ontario Graduate Scholarship for Science and Technology (to J.W.); and by a New Investigator Award from the CIHR (to C.P.).

PII: S0016-5085(09)01389-4

doi: 10.1053/j.gastro.2009.07.064

Gastroenterology
Volume 137, Issue 5 , Pages 1795-1804 , November 2009