Gastroenterology
Volume 137, Issue 5 , Pages 1746-1756.e1 , November 2009

An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice

  • Kanna Kobayashi

      Affiliations

    • Gastroenterology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
  • ,
  • Shuo–Wang Qiao

      Affiliations

    • Rikshospitalet University Hospital, Oslo, Norway
  • ,
  • Masaru Yoshida

      Affiliations

    • Gastrointestinal Center for Medical Research, Kobe University School of Medicine, Kobe, Japan
  • ,
  • Kristi Baker

      Affiliations

    • Gastroenterology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
  • ,
  • Wayne I. Lencer

      Affiliations

    • Gastroenterology Division, Children's Hospital Boston, Harvard Medical School, Boston Massachusetts
  • ,
  • Richard S. Blumberg

      Affiliations

    • Gastroenterology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
    • Corresponding Author InformationReprint requests Address requests for reprints to: Richard S. Blumberg, MD, Gastroenterology Division, Brigham and Women's Hospital, 75 Francis St, Boston, Massachusetts 02115. fax: (617) 264-5185

Received 12 May 2009 ,Accepted 22 July 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by NIH DK53056 and the Harvard Digestive Diseases Center (DK034854) (to R.S.B. and W.I.L.), by NIH DK44319 and DK51362 (to R.S.B.), and by Crohn's and Colitis Foundation of America (to W.I.L.).

PII: S0016-5085(09)01382-1

doi: 10.1053/j.gastro.2009.07.059

Gastroenterology
Volume 137, Issue 5 , Pages 1746-1756.e1 , November 2009