Gastroenterology
Volume 137, Issue 5 , Pages 1621-1627, November 2009

Calculation of Risk of Colorectal and Endometrial Cancer Among Patients With Lynch Syndrome

  • Elena Stoffel

      Affiliations

    • Brigham and Women's Hospital, Boston, Massachusetts
    • Dana-Farber Cancer Institute, Boston, Massachusetts
  • ,
  • Bhramar Mukherjee

      Affiliations

    • Department of Biostatistics, University of Michigan Medical School and School of Public Health, Ann Arbor, Michigan
  • ,
  • Victoria M. Raymond

      Affiliations

    • Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
  • ,
  • Nabihah Tayob

      Affiliations

    • Department of Biostatistics, University of Michigan Medical School and School of Public Health, Ann Arbor, Michigan
  • ,
  • Fay Kastrinos

      Affiliations

    • Brigham and Women's Hospital, Boston, Massachusetts
  • ,
  • Jennifer Sparr

      Affiliations

    • Dana-Farber Cancer Institute, Boston, Massachusetts
  • ,
  • Fei Wang

      Affiliations

    • Department of Biostatistics, University of Michigan Medical School and School of Public Health, Ann Arbor, Michigan
  • ,
  • Prathap Bandipalliam

      Affiliations

    • Dana-Farber Cancer Institute, Boston, Massachusetts
  • ,
  • Sapna Syngal

      Affiliations

    • Brigham and Women's Hospital, Boston, Massachusetts
    • Dana-Farber Cancer Institute, Boston, Massachusetts
  • ,
  • Stephen B. Gruber

      Affiliations

    • Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
    • Department of Epidemiology and Human Genetics, University of Michigan Medical School and School of Public Health, Ann Arbor, Michigan
    • Corresponding Author InformationReprint requests Address requests for reprints to: Stephen B. Gruber, MD, MPH, PhD, Division of Epidemiology and Human Genetics, University of Michigan School of Public Health, 1524 BSRB, Ann Arbor, Michigan 48105. fax: (734) 647-7950

Received 8 May 2009; accepted 8 July 2009. published online 21 July 2009.

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 E.S. and B.M. contributed equally to this work.

 Conflict of interest The authors disclose the following: Dr Syngal and Dr Gruber have been external advisors to Myriad Genetic Laboratories. The remaining authors disclose no conflicts.

 Funding This work was supported in part by the National Cancer Institute (RO1 CA81488 to S.B.G., K07 CA 120448-01-A2 to E.S., and K24 CA 113433 to S.S., R03 CA130045 to B.M.), the University of Michigan's Cancer Center Support Grant (5 P30 CA46592).

PII: S0016-5085(09)01158-5

doi:10.1053/j.gastro.2009.07.039

Gastroenterology
Volume 137, Issue 5 , Pages 1621-1627, November 2009