Gastroenterology
Volume 137, Issue 4 , Pages 1425-1434 , October 2009

Activation of Human Enteric Neurons by Supernatants of Colonic Biopsy Specimens From Patients With Irritable Bowel Syndrome

  • Sabine Buhner

      Affiliations

    • Human Biology, Technische Universität München, Freising, Germany
    • ,
  • Qin Li

      Affiliations

    • Human Biology, Technische Universität München, Freising, Germany
    • Department of Physiology, Shangdong University, Shangdong, China
    • ,
  • Sheila Vignali

      Affiliations

    • Human Biology, Technische Universität München, Freising, Germany
    • ,
  • Giovanni Barbara

      Affiliations

    • Department of Clinical Medicine and Center for Applied Biomedical Research (CRBA), St. Orsola Hospital, Bologna, Italy
    • ,
  • Roberto De Giorgio

      Affiliations

    • Department of Clinical Medicine and Center for Applied Biomedical Research (CRBA), St. Orsola Hospital, Bologna, Italy
    • ,
  • Vincenzo Stanghellini

      Affiliations

    • Department of Clinical Medicine and Center for Applied Biomedical Research (CRBA), St. Orsola Hospital, Bologna, Italy
    • ,
  • Cesare Cremon

      Affiliations

    • Department of Clinical Medicine and Center for Applied Biomedical Research (CRBA), St. Orsola Hospital, Bologna, Italy
    • ,
  • Florian Zeller

      Affiliations

    • Department of Surgery, Klinikum Freising, Freising, Germany
    • ,
  • Rupert Langer

      Affiliations

    • Department of Pathology, Technische Universität München, München, Germany
    • ,
  • Hannelore Daniel

      Affiliations

    • Molecular Nutrition Unit, Technische Universität München, Freising, Germany
    • ,
  • Klaus Michel

      Affiliations

    • Human Biology, Technische Universität München, Freising, Germany
    • ,
  • Michael Schemann

      Affiliations

    • Human Biology, Technische Universität München, Freising, Germany
    • Corresponding Author InformationReprint requests Address requests for reprints to: Michael Schemann, PhD, Prof, Human Biology, Technische Universität München, Hochfeldweg 2 85350 Freising-Weihenstephan; Germany. fax: (49) 8161 715785

Received 11 March 2009 ,Accepted 7 July 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by Deutsche Forschungsgemeinschaft DFG Sche-267/7-1 (to M.S.); European Union 7th Framework Programme (IPODD) (to M.S.); Italian Ministry of University and Research (COFIN Projects to G.B., R.D.G.), R.F.O. funds from the University of Bologna (to R.D.G., V.S., G.B.), and a grant from the “Fondazione Del Monte di Bologna e Ravenna” (Bologna, Italy; to R.D.G.).

PII: S0016-5085(09)01152-4

doi: 10.1053/j.gastro.2009.07.005

Gastroenterology
Volume 137, Issue 4 , Pages 1425-1434 , October 2009

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