Gastroenterology
Volume 137, Issue 4 , Pages 1270-1279, October 2009

Intraepithelial Effector (CD3+)/Regulatory (FoxP3+) T-Cell Ratio Predicts a Clinical Outcome of Human Colon Carcinoma

  • Frank A. Sinicrope

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Frank A. Sinicrope, MD, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905
    • Miles and Shirley Fiterman Digestive Disease Center, Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota
    • Miles and Shirley Fiterman Digestive Disease Center, Division of Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Rafaela L. Rego

      Affiliations

    • Miles and Shirley Fiterman Digestive Disease Center, Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, Minnesota
    • Miles and Shirley Fiterman Digestive Disease Center, Division of Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Stephen M. Ansell

      Affiliations

    • Miles and Shirley Fiterman Digestive Disease Center, Division of Hematology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Keith L. Knutson

      Affiliations

    • Miles and Shirley Fiterman Digestive Disease Center, Division of Immunology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Nathan R. Foster

      Affiliations

    • Miles and Shirley Fiterman Digestive Disease Center, Division of Biostatistics, Mayo Clinic, Rochester, Minnesota
    • ,
  • Daniel J. Sargent

      Affiliations

    • Miles and Shirley Fiterman Digestive Disease Center, Division of Biostatistics, Mayo Clinic, Rochester, Minnesota

Received 18 July 2008; accepted 24 June 2009. published online 06 July 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported in part by National Cancer Institute grant CA104683-02 (to F.A.S.) and National Cancer Institute core grant CA15083 (to the Mayo Clinic Cancer Center).

PII: S0016-5085(09)01138-X

doi:10.1053/j.gastro.2009.06.053

Gastroenterology
Volume 137, Issue 4 , Pages 1270-1279, October 2009

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