Gastroenterology
Volume 137, Issue 5 , Pages 1725-1735 , November 2009

Targeted Metabolomics Identifies Glucuronides of Dietary Phytoestrogens as a Major Class of MRP3 Substrates In Vivo

  • Koen van de Wetering

      Affiliations

    • Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    • ,
  • Wouter Feddema

      Affiliations

    • Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    • ,
  • J. Bernd Helms

      Affiliations

    • Department of Biochemistry and Cell Biology, Faculty of Veterinary Science, Utrecht University, The Netherlands
    • ,
  • Jos F. Brouwers

      Affiliations

    • Department of Biochemistry and Cell Biology, Faculty of Veterinary Science, Utrecht University, The Netherlands
    • ,
  • Piet Borst

      Affiliations

    • Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    • Corresponding Author InformationCorrespondence Address correspondence to: Piet Borst, MD, Division of Molecular Biology (H8), Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. fax: (31) 20-669 1383

Received 3 April 2009 ,Accepted 25 June 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by ZonMw for the experimental work in our laboratory (TOP grant number 40-00812-98-07-028, to K.vdW. and P.B.).

PII: S0016-5085(09)01137-8

doi: 10.1053/j.gastro.2009.06.052

Gastroenterology
Volume 137, Issue 5 , Pages 1725-1735 , November 2009

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