Gastroenterology
Volume 137, Issue 2 , Pages 422-424 , August 2009

New Insights into the Role of Hedgehog Signaling in Gastrointestinal Development and Cancer

  • Byeong–Moo Kim
  • ,
  • Michael Y. Choi

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Michael Y. Choi, MD, Massachusetts General Hospital, Jackson 822, 55 Fruit Street, Boston, Massachusetts 02114

  • Image Result

    Arimura et al propose that an activating signal from Smo, a pivotal molecule in Hh pathway, increases nuclear β-catenin level and consequently transcribes Wnt downstream targets.

    Arimura et al propose that an activating signal from Smo, a pivotal molecule in Hh pathway, increases nuclear β-catenin level and consequently transcribes Wnt downstream targets.

 Conflicts of interest The authors disclose no conflicts.

PII: S0016-5085(09)00990-1

doi: 10.1053/j.gastro.2009.06.021

Gastroenterology
Volume 137, Issue 2 , Pages 422-424 , August 2009