Gastroenterology
Volume 137, Issue 3 , Pages 815-823 , September 2009

Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett's Esophagus

  • Ganapathy A. Prasad

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Tsung Teh Wu

      Affiliations

    • Department of Laboratory Medicine and Anatomic Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Dennis A. Wigle

      Affiliations

    • Division of General Thoracic Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Navtej S. Buttar

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Louis–Michel Wongkeesong

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Kelly T. Dunagan

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Lori S. Lutzke

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Lynn S. Borkenhagen

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
  • ,
  • Kenneth K. Wang

      Affiliations

    • Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota
    • Corresponding Author InformationReprint requests Kenneth K. Wang, MD, Alfred Main, St. Mary's Hospital, 200, First Street SW, Rochester, Minnesota. fax: (507) 255-7612

Received 6 February 2009 ,Accepted 29 May 2009.

  • Image Result

    Flowsheet of patients treated with endoscopic therapy.

    Flowsheet of patients treated with endoscopic therapy.

  • Image Result

    Overall survival in the ENDO and SURG groups (Kaplan–Meier curves). Black line: ENDO group; gray line: SURG group. Log-rank test, P = .15.

    Overall survival in the ENDO and SURG groups (Kaplan–Meier curves). Black line: ENDO group; gray line: SURG group. Log-rank test, P = .15.

  • Image Result

    Cancer-free survival in the ENDO and SURG groups (Kaplan–Meier curves). Black line: ENDO group; gray line: SURG group. Log-rank test, P = .01.

    Cancer-free survival in the ENDO and SURG groups (Kaplan–Meier curves). Black line: ENDO group; gray line: SURG group. Log-rank test, P = .01.

 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by National Institutes of Health grants R01CA111603-01A1 (K.K.W.), R01CA097048 (K.K.W.), R21CA122426-01 (K.K.W.), and R03CA135991-01 (G.A.P.), and the Shirley and Miles Fiterman Digestive Disease Center.

PII: S0016-5085(09)00914-7

doi: 10.1053/j.gastro.2009.05.059

Gastroenterology
Volume 137, Issue 3 , Pages 815-823 , September 2009