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Gastroenterology
Volume 137, Issue 3
, Pages 885-891.e1
, September 2009
Secondary Prophylaxis of Hepatic Encephalopathy: An Open-Label Randomized Controlled Trial of Lactulose Versus Placebo
References
- Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patients. J Hepatol. 2001;35:37–45
- Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathy. Am J Gastroenterol. 2001;96:2718–2723
- Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: a meta-analysis. Hepatology. 1999;30:612–622
- Portosystemic hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: clinical, laboratory, psychometric, and electroencephalographic investigations. Hepatology. 1998;28:1215–1225
- Screening of subclinical hepatic encephalopathy. J Hepatol. 2000;32:748–753
- Auditory P300 event-related potentials and number connection test for evaluation of subclinical hepatic encephalopathy in patients with cirrhosis of the liver: a follow-up study. J Gastroenterol Hepatol. 2001;16:322–327
- . Quality of life in cirrhotics with minimal hepatic encephalopathy. Metab Brain Dis. 2001;16:37–41
- Critical flicker frequency: diagnostic tool for minimal hepatic encephalopathy. J Hepatol. 2007;47:67–73
- Value of the critical flicker frequency in patients with minimal hepatic encephalopathy. Hepatology. 2007;45:879–885
- Prognostic significance of hepatic encephalopathy in patients with cirrhosis. J Hepatol. 1999;30:890–895
- Treatment of hepatic encephalopathy (New perspectives on old ideas). In: Butterworth RF, Pomier-Layrargues G editor. Hepatic encephalopathy (Pathophysiology and treatment). Clifton, NJ: Humana; 1987;p. 469–481
- . Hepatic encephalopathy. Am J Gastroenterol. 2001;96:1968–1976
- . Treatment of hepatic encephalopathy. N Engl J Med. 1997;337:473–479
- Lactulose ingestion increases faecal bifidobacterial counts: a randomised double-blind study in healthy humans. Eur J Clin Nutr. 2004;58:462–466
- Comparison of lactulose and neomycin in the treatment of chronic portal systemic encephalopathy. Gastroenterology. 1977;72:573–583
- . Neomycin-sorbitol and lactulose in the treatment of acute portal-systemic encephalopathy (A controlled, double-blind clinical trial). Am J Dig Dis. 1978;23:398–406
- Lactitol in treatment of chronic hepatic encephalopathy (A meta-analysis). Dig Dis Sci. 1993;38:916–922
- . Nonabsorbable disaccharides for hepatic encephalopathy: systematic review of randomised trials. BMJ. 2004;328:1046–1051
- Therapeutic efficacy of 1-ornithine-l-aspartate infusion concentrate in patients with liver cirrhosis and hepatic encephalopathy: a placebo-controlled double-blind study. Hepatology. 1997;25:1351–1360
- 1-ornithine-l-aspartate granulate in the treatment of latent and mild chronic hepatic encephalopathy (HE): a placebo controlled double-blind study. J Hepatol. 1998;28:856–864
- . Treatment of hepatic encephalopathy with metronidazole. Gut. 1982;23:1–7
- Neomycin reduces the intestinal production of ammonia from glutamine. Adv Exp Med Biol. 1994;368:125–134
- Rifaximin, a non-absorbable rifamycin, for the treatment of hepatic encephalopathy (A double-blind, randomized trial). Curr Med Res Opin. 1997;13:593–601
- Efficacy of lactulose in cirrhotic patients with subclinical hepatic encephalopathy. Dig Dis Sci. 2000;45:1549–1552
- Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy. Hepatology. 1997;26:1410–1414
- Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy. Hepatology. 2007;45:549–559
- An open-label randomized controlled trial of lactulose and probiotics in the treatment of minimal hepatic encephalopathy. Eur J Gastroenterol Hepatol. 2008;20:506–511
- Hepatic encephalopathy—definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology. 2002;35:716–721
- Figure connection tests: a universal test for assessment of mental state. J Gastroenterol Hepatol. 1995;10:14–23
- . Manual of Indian Adaptation of WAIS Performance Scale. Delhi: Manasayan. 1974;2–:29
- Lactitol in prevention of recurrent episodes of hepatic encephalopathy in cirrhotic patients with portal-systemic shunt. Dig Dis Sci. 1989;34:823–829
- . Review article: the burden of hepatic encephalopathy. Aliment Pharmacol Ther. 2007;25(Suppl 1):3–9
- . Lactitol vs. lactulose in the treatment of acute hepatic encephalopathy in cirrhotic patients: a double-blind, randomized trial. Hepatology. 1987;7:1278–1284
- Lactitol versus lactulose in the treatment of acute portal systemic encephalopathy (PSE) (A controlled trial). J Hepatol. 1987;4:293–298
- Lactitol vs. lactulose in the treatment of chronic recurrent portal-systemic encephalopathy. J Hepatol. 1988;7:106–110
- . Lactitol versus lactulose in the treatment of chronic hepatic encephalopathy (A double-blind, randomised, cross-over study). J Hepatol. 1987;4:236–244
- . Lactitol in the treatment of chronic hepatic encephalopathy: an open comparison with lactulose. Gut. 1985;26:415–420
- Prevalence and natural history of subclinical hepatic encephalopathy in cirrhosis. J Gastroenterol Hepatol. 2001;16:531–535
- The prognostic significance of subclinical hepatic encephalopathy. Am J Gastroenterol. 2000;95:2029–2034
- . A prospective study of bacterial infections in patients with cirrhosis. J Hepatol. 1993;18:353–358
- . Risk factors for the development of bacterial infections in hospitalized patients with cirrhosis. Am J Gastroenterol. 1999;94:2193–2197
- Intestinal permeability in liver cirrhosis: relationship with severe septic complications. Eur J Gastroenterol Hepatol. 1999;11:755–759
- Intestinal permeability is increased in patients with advanced cirrhosis. Hepatogastroenterology. 2003;50:1482–1486
- . Hepatic encephalopathy. Med Clin North Am. 2008;92:795–812
- . Lactulose, disaccharides and colonic flora. Drugs. 1997;53:930–942
- Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis. Hepatology. 2004;39:1441–1449
Conflicts of interest The authors disclose no conflicts.
PII: S0016-5085(09)00904-4
doi: 10.1053/j.gastro.2009.05.056
© 2009 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 137, Issue 3
, Pages 885-891.e1
, September 2009

