Gastroenterology
Volume 137, Issue 3 , Pages 997-1005.e4 , September 2009

Glucagon-Like Peptide-2 Increases Intestinal Lipid Absorption and Chylomicron Production via CD36

  • Joanne Hsieh

      Affiliations

    • Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada
    • Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Christine Longuet

      Affiliations

    • Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Adriano Maida

      Affiliations

    • Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Jasmine Bahrami

      Affiliations

    • Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Elaine Xu

      Affiliations

    • Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada
    • ,
  • Christopher L. Baker

      Affiliations

    • Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada
    • ,
  • Patricia L. Brubaker

      Affiliations

    • Department of Physiology, University of Toronto, Toronto, Ontario, Canada
    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Daniel J. Drucker

      Affiliations

    • Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Khosrow Adeli

      Affiliations

    • Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada
    • Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationReprint requests Address requests for reprints to: Khosrow Adeli, MD, Division of Clinical Biochemistry, DPLM, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Atrium Room 3652, Toronto, Ontario, Canada, M5G 1X8. fax: (416) 813-6257

Received 17 September 2008 ,Accepted 20 May 2009.

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 Conflicts of interest The authors disclose the following: Daniel J. Drucker (Dr Drucker is a party to a licensing agreement among the University of Toronto, the University Health Network, and NPS Pharmaceuticals Inc in regard to the clinical development of GLP-2). The remaining authors disclose no conflicts.

 Funding Supported by CIHR grant MOP-53093 (to K.A.) and CIHR grant MOP-14799 (to D.J.D.). J.H. is supported by the NSERC CGS M, Restracomp, and CIHR CGS D fellowships.

PII: S0016-5085(09)00868-3

doi: 10.1053/j.gastro.2009.05.051

Gastroenterology
Volume 137, Issue 3 , Pages 997-1005.e4 , September 2009

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