Gastroenterology
Volume 137, Issue 3 , Pages 1083-1092 , September 2009

Reducing Extracellular pH Sensitizes the Acinar Cell to Secretagogue-Induced Pancreatitis Responses in Rats

  • Madhavi Bhoomagoud

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Thomas Jung

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Jorunn Atladottir

      Affiliations

    • Department of Surgery, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Thomas R. Kolodecik

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Christine Shugrue

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Anamika Chaudhuri

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Edwin C. Thrower

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Fred S. Gorelick

      Affiliations

    • Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
    • Department of Veterans Affairs Connecticut Healthcare, West Haven, Connecticut
    • Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut
    • Corresponding Author InformationReprint requests Address requests for reprints to: Fred Gorelick, MD, Room # D 226, Bldg. 4, VA Medical Center 950 Campbell Avenue West Haven, Connecticut 06516

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by grants from the NIH NRSA to MB (DK80582); NIH T32 award to TJ (DK07017): Veterans Administration Merit Award to FG; and NIH R01 (DK54021) to FG.

PII: S0016-5085(09)00773-2

doi: 10.1053/j.gastro.2009.05.041

Gastroenterology
Volume 137, Issue 3 , Pages 1083-1092 , September 2009

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