Gastroenterology
Volume 137, Issue 2 , Pages 629-638, August 2009

Reduced Level of Smoothened Suppresses Intestinal Tumorigenesis by Down-Regulation of Wnt Signaling

Department of Pharmacology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Received 19 November 2008; accepted 27 April 2009. published online 08 May 2009.

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 M.A. and M.M.T. are senior authors.

 A.M.'s current address is Burnham Institute for Medical Research, La Jolla, California.

 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by Grants-in-Aid of Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (to M.M.T.).

PII: S0016-5085(09)00739-2

doi:10.1053/j.gastro.2009.04.059

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Gastroenterology
Volume 137, Issue 2 , Pages 629-638, August 2009